IE780208L - IMIDAZO [1,5-d] TRIAZINE DERIVATIVES - Google Patents

IMIDAZO [1,5-d] TRIAZINE DERIVATIVES

Info

Publication number
IE780208L
IE780208L IE780208A IE20878A IE780208L IE 780208 L IE780208 L IE 780208L IE 780208 A IE780208 A IE 780208A IE 20878 A IE20878 A IE 20878A IE 780208 L IE780208 L IE 780208L
Authority
IE
Ireland
Prior art keywords
formula
image
compounds
meanings given
imidazo
Prior art date
Application number
IE780208A
Other versions
IE46511B1 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/843,174 external-priority patent/US4107307A/en
Priority claimed from US05/848,836 external-priority patent/US4124766A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IE780208L publication Critical patent/IE780208L/en
Publication of IE46511B1 publication Critical patent/IE46511B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/40—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

New compounds of the formula: <IMAGE> in which R1, R2, R4 and X have the meanings given in Claim 1 can be used for the pre-emergence or post-emergence control of monocotyledon and dicotyledon plant species and for inhibiting the enzyme phosphodiesterase in humans and other mammals. Some of the compounds of the formula I are prepared from new compounds of the formula: <IMAGE> in which R, R1, R2 and X have the meanings given in Claim 6 by heating in a nonpolar solvent followed optionally by chlorination or bromination. The compounds of the formula II in which R, R1, R2 have the meanings given in Claim 8 and X represents oxygen or sulphur are obtained by condensation of a 4-imidazolecarboxaldehyde of the formula: <IMAGE> with a compound of the formula: H2N-NH-CX2R.h [GB1597671A]
IE208/78A 1977-02-03 1978-01-31 Herbidical compositions IE46511B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76531777A 1977-02-03 1977-02-03
US76531877A 1977-02-03 1977-02-03
US84317377A 1977-10-18 1977-10-18
US05/843,174 US4107307A (en) 1977-02-03 1977-10-18 Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones
US05/848,836 US4124766A (en) 1977-02-03 1977-11-07 Substituted 3-(4-imidazolylmethylene)carbazic and thiocarbazic acid esters

Publications (2)

Publication Number Publication Date
IE780208L true IE780208L (en) 1978-08-03
IE46511B1 IE46511B1 (en) 1983-07-13

Family

ID=27542181

Family Applications (1)

Application Number Title Priority Date Filing Date
IE208/78A IE46511B1 (en) 1977-02-03 1978-01-31 Herbidical compositions

Country Status (15)

Country Link
JP (1) JPS596316B2 (en)
AR (1) AR224613A1 (en)
BE (1) BE863567A (en)
CA (1) CA1097638A (en)
CH (1) CH636615A5 (en)
DE (1) DE2804435A1 (en)
DK (1) DK48778A (en)
FR (1) FR2384772A1 (en)
GB (1) GB1597671A (en)
GR (1) GR73810B (en)
IE (1) IE46511B1 (en)
IL (1) IL53783A (en)
NL (1) NL7801230A (en)
SE (1) SE7801270L (en)
YU (1) YU22078A (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3212749A1 (en) * 1982-04-06 1983-10-13 Basf Ag, 6700 Ludwigshafen NEW 5-SUBSTITUTED 4-METHYLIMIDAZOLES AND METHOD FOR THEIR PRODUCTION
DE3302413A1 (en) * 1983-01-21 1984-07-26 Schering AG, 1000 Berlin und 4709 Bergkamen TRIAZINONE, METHOD FOR PRODUCING THESE COMPOUNDS AND THEIR CONTAINING MEANS WITH SELECTIVE HERBICIDAL ACTION
JPS6337712A (en) * 1986-08-01 1988-02-18 Hitachi Ltd Protecting circuit for field-effect transistor
JPH02185069A (en) * 1988-12-02 1990-07-19 Motorola Inc Semiconductor device having high-energy stopping power and temperature-compensated stopping voltage
RU2103262C1 (en) * 1992-07-16 1998-01-27 Лонца АГ Гампель/Валлис Method for production of 2-substituted 5-chloroimidazole-4-carbaldehydes
DK0614890T3 (en) * 1993-03-12 1997-10-13 Lonza Ag Process for preparing optionally 2-substituted 5-chloroimidazoles.
US5484939A (en) * 1993-03-12 1996-01-16 Lonza Ltd. 2-substituted 5-chlorimidazoles
US5442075A (en) * 1993-03-12 1995-08-15 Lonza Ltd. Process for the production of 2-substituted 5-chlorimidazole-4-carbaldehydes
CA2135541C (en) * 1993-11-15 2006-01-10 Gareth Griffiths Process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes
CA2175420C (en) * 1995-05-17 2007-04-10 Gareth Griffiths Process for the preparation of optionally 2-substituted 5-chloroimidazole-4-carbaldehydes
JP4103149B2 (en) 1996-01-05 2008-06-18 ロンザ リミテッド Process for producing 2-substituted 5-chloroimidazole-4-carbaldehyde
FR2842809A1 (en) * 2002-07-26 2004-01-30 Greenpharma Sas NOVEL SUBSTITUTED PYRAZOLO [1,5-a] -1,3,5-TRIAZINES AND THEIR ANALOGUES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, USE AS A MEDICAMENT AND METHODS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
YU22078A (en) 1983-12-31
GR73810B (en) 1984-04-17
SE7801270L (en) 1978-09-29
FR2384772A1 (en) 1978-10-20
IL53783A (en) 1982-08-31
JPS5398994A (en) 1978-08-29
JPS596316B2 (en) 1984-02-10
CA1097638A (en) 1981-03-17
BE863567A (en) 1978-08-02
CH636615A5 (en) 1983-06-15
NL7801230A (en) 1978-08-07
IE46511B1 (en) 1983-07-13
GB1597671A (en) 1981-09-09
DE2804435A1 (en) 1978-08-17
IL53783A0 (en) 1978-04-30
DK48778A (en) 1978-08-04
AR224613A1 (en) 1981-12-30

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