CH636127A5 - Process for the preparation of the novel antibiotic MSD890A9 - Google Patents
Process for the preparation of the novel antibiotic MSD890A9 Download PDFInfo
- Publication number
- CH636127A5 CH636127A5 CH1401377A CH1401377A CH636127A5 CH 636127 A5 CH636127 A5 CH 636127A5 CH 1401377 A CH1401377 A CH 1401377A CH 1401377 A CH1401377 A CH 1401377A CH 636127 A5 CH636127 A5 CH 636127A5
- Authority
- CH
- Switzerland
- Prior art keywords
- fractions
- antibiotic
- medium
- methanol
- column
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74295776A | 1976-11-17 | 1976-11-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH636127A5 true CH636127A5 (en) | 1983-05-13 |
Family
ID=24986923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1401377A CH636127A5 (en) | 1976-11-17 | 1977-11-16 | Process for the preparation of the novel antibiotic MSD890A9 |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS5363396A (da) |
CH (1) | CH636127A5 (da) |
DE (1) | DE2751260A1 (da) |
DK (1) | DK487877A (da) |
ES (1) | ES463972A1 (da) |
FR (1) | FR2371447A1 (da) |
GB (1) | GB1592807A (da) |
NL (1) | NL7712091A (da) |
PT (1) | PT67267B (da) |
SE (1) | SE433620B (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH16708A (en) | 1978-07-24 | 1984-01-20 | Merck & Co Inc | Z-2-acylamino-3-monosubstituted propenoates |
DE2966446D1 (en) * | 1978-09-09 | 1984-01-05 | Beecham Group Plc | Beta-lactam compounds, their preparation and use |
US4530791A (en) * | 1979-04-16 | 1985-07-23 | Kowa Co., Ltd. | β-Lactam antibiotics |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1489235A (en) * | 1974-03-28 | 1977-10-19 | Beecham Group Ltd | Antibiotics |
JPS5283992A (en) * | 1976-01-01 | 1977-07-13 | Beecham Group Ltd | Novel antibiotic |
-
1977
- 1977-11-02 DK DK487877A patent/DK487877A/da unknown
- 1977-11-02 NL NL7712091A patent/NL7712091A/xx not_active Application Discontinuation
- 1977-11-03 SE SE7712429A patent/SE433620B/xx not_active IP Right Cessation
- 1977-11-08 ES ES463972A patent/ES463972A1/es not_active Expired
- 1977-11-11 PT PT67267A patent/PT67267B/pt unknown
- 1977-11-14 GB GB47323/77A patent/GB1592807A/en not_active Expired
- 1977-11-16 CH CH1401377A patent/CH636127A5/de not_active IP Right Cessation
- 1977-11-16 FR FR7734456A patent/FR2371447A1/fr active Granted
- 1977-11-16 DE DE19772751260 patent/DE2751260A1/de not_active Ceased
- 1977-11-17 JP JP13735577A patent/JPS5363396A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB1592807A (en) | 1981-07-08 |
ES463972A1 (es) | 1978-11-16 |
SE433620B (sv) | 1984-06-04 |
PT67267B (en) | 1979-10-08 |
DK487877A (da) | 1978-05-18 |
FR2371447A1 (fr) | 1978-06-16 |
JPS5363396A (en) | 1978-06-06 |
PT67267A (en) | 1977-12-01 |
NL7712091A (nl) | 1978-05-19 |
DE2751260A1 (de) | 1978-05-24 |
FR2371447B1 (da) | 1980-07-04 |
SE7712429L (sv) | 1978-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |