CH633446A5 - Long-acting papaveroline derivative and process for obtaining it - Google Patents

Long-acting papaveroline derivative and process for obtaining it Download PDF

Info

Publication number
CH633446A5
CH633446A5 CH587778A CH587778A CH633446A5 CH 633446 A5 CH633446 A5 CH 633446A5 CH 587778 A CH587778 A CH 587778A CH 587778 A CH587778 A CH 587778A CH 633446 A5 CH633446 A5 CH 633446A5
Authority
CH
Switzerland
Prior art keywords
papaveroline
ester
tetra
oco
nicotinic
Prior art date
Application number
CH587778A
Other languages
English (en)
Italian (it)
Inventor
Massimo Fazzini
Original Assignee
Scharper Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scharper Spa filed Critical Scharper Spa
Publication of CH633446A5 publication Critical patent/CH633446A5/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH587778A 1977-05-30 1978-05-30 Long-acting papaveroline derivative and process for obtaining it CH633446A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT24141/77A IT1143667B (it) 1977-05-30 1977-05-30 Derivato paraverolinico ad azione duratura e procedimento per ottenerlo

Publications (1)

Publication Number Publication Date
CH633446A5 true CH633446A5 (en) 1982-12-15

Family

ID=11212187

Family Applications (1)

Application Number Title Priority Date Filing Date
CH587778A CH633446A5 (en) 1977-05-30 1978-05-30 Long-acting papaveroline derivative and process for obtaining it

Country Status (13)

Country Link
JP (1) JPS53149982A (xx)
BE (1) BE867515A (xx)
BR (1) BR7803416A (xx)
CA (1) CA1084504A (xx)
CH (1) CH633446A5 (xx)
DE (1) DE2822186A1 (xx)
ES (1) ES470343A1 (xx)
FR (1) FR2392987A1 (xx)
GB (1) GB1593598A (xx)
GR (1) GR63731B (xx)
IT (1) IT1143667B (xx)
MX (1) MX5515E (xx)
PT (1) PT68115A (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA803993B (en) * 1979-07-19 1981-07-29 Buzas Andre New isoquinoline derivatives and preparation thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1175246B (de) * 1959-12-14 1964-08-06 Orsymonde Fa Verfahren zur Herstellung des Dimethylpapa-verolin-bis-nicotinsaeureesters und seines sauren Dimaleats
FR794M (xx) * 1960-12-02 1961-09-11

Also Published As

Publication number Publication date
IT1143667B (it) 1986-10-22
BR7803416A (pt) 1979-01-02
JPS572715B2 (xx) 1982-01-18
JPS53149982A (en) 1978-12-27
CA1084504A (en) 1980-08-26
MX5515E (es) 1983-09-14
BE867515A (fr) 1978-09-18
GR63731B (en) 1979-12-04
DE2822186A1 (de) 1978-12-14
ES470343A1 (es) 1979-01-01
PT68115A (en) 1978-06-01
FR2392987B1 (xx) 1982-04-23
GB1593598A (en) 1981-07-22
FR2392987A1 (fr) 1978-12-29

Similar Documents

Publication Publication Date Title
JP3272357B2 (ja) 抗増殖性キナゾリン
DE69422044T2 (de) 2-aminoindane als selektive dopamin-d3-liganden
FI62093C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 4,0-dihydro-10-oxotieno(3,2-c)benzoxepin-8-aettiksyror samt dras esterderivat
DD273833A5 (de) N 9 - cyclopentylsubstituierte adeninderivate
WO2008014661A1 (fr) Composés de tétrahydroprotoberbérine, leur production, leur composition médicinale et leurs utilisations
KR20080039987A (ko) 4-아미노-티에노[3,2-c]피리딘-7-카르복실산 유도체
BR112020006185A2 (pt) derivado de anel fundido utilizado como inibidor de receptor a2a
SK283536B6 (sk) Pyridylftalazindióny, spôsob ich prípravy a použitie a farmaceutické prostriedky na ich báze
JPS5899479A (ja) ピリミドキノキサリン誘導体
US4567163A (en) Salicyclic acid derivatives of N-acetylcysteine and pharmacological use thereof
SK147897A3 (en) Azacycloalcane derivatives, preparation thereof and their applications in therapy
DE2635516A1 (de) Neue derivate des thiazolo-eckige klammer auf 3,4-b eckige klammer zu-isochinolins, ihre herstellung und die sie enthaltenden zusammensetzungen
IT8049163A1 (it) Fenossiammine eterocicliche sostituite, procedimento per prepararle e composizioni farmaceutiche che le contengono.
CN113336735A (zh) 一种尿石素类化合物、制备方法、药物组合物及用途
DE2800596A1 (de) 4,5,6,7-tetrahydrothieno(2,3-c) und -(3,2-c)pyridine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
CH633446A5 (en) Long-acting papaveroline derivative and process for obtaining it
AU624907B2 (en) Aralkylamine compounds
Wehle et al. Investigation into the stability and reactivity of the pentacyclic alkaloid dehydroevodiamine and the benz-analog thereof
US3872108A (en) Novel chromone derivatives and the production thereof
CN1325476C (zh) 通过偶氮甲碱叶立德的闭环制备稠多环生物碱,其新化合物和其作为化疗剂的应用
Robison et al. The Rearrangement of Isoquinoline-N-Oxides. II. Observations with N-Hydroxyisocarbostyrils and Other Substituted Derivatives1
Brown Improved syntheses in the pyrimidine series. IV. N‐methyl derivatives of 4: 5‐diaminopyrimidine
DE3226516A1 (de) Substituierte thiazolo(3,2-a)pyrimidine, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese verbindungen enthalten
FI59097C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara pyrimido(4,5-b)kinolin-4(3h)-oni-2-karboxylsyraderivat
KR960014352B1 (ko) 치환된 테트라하이드로이소퀴놀린 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물

Legal Events

Date Code Title Description
PL Patent ceased