CH632760A5 - Process for preparing ethers of clavulanic esters - Google Patents

Process for preparing ethers of clavulanic esters Download PDF

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Publication number
CH632760A5
CH632760A5 CH252678A CH252678A CH632760A5 CH 632760 A5 CH632760 A5 CH 632760A5 CH 252678 A CH252678 A CH 252678A CH 252678 A CH252678 A CH 252678A CH 632760 A5 CH632760 A5 CH 632760A5
Authority
CH
Switzerland
Prior art keywords
general formula
group
esters
clavulanic acid
ethyl
Prior art date
Application number
CH252678A
Other languages
German (de)
English (en)
Inventor
Thomas Trefor Howarth
Roger John Ponsford
Kong Luk
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB10082/77A external-priority patent/GB1582864A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of CH632760A5 publication Critical patent/CH632760A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH252678A 1977-03-10 1978-03-08 Process for preparing ethers of clavulanic esters CH632760A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB10082/77A GB1582864A (en) 1977-03-10 1977-03-10 Chemical process for the preparation of clavulanic acid derivatives
GB1011677 1977-03-10

Publications (1)

Publication Number Publication Date
CH632760A5 true CH632760A5 (en) 1982-10-29

Family

ID=26247246

Family Applications (1)

Application Number Title Priority Date Filing Date
CH252678A CH632760A5 (en) 1977-03-10 1978-03-08 Process for preparing ethers of clavulanic esters

Country Status (19)

Country Link
JP (1) JPS53112894A (sv)
AR (1) AR216505A1 (sv)
AT (1) AT359188B (sv)
AU (1) AU519232B2 (sv)
CH (1) CH632760A5 (sv)
DE (1) DE2808116A1 (sv)
DK (1) DK139377A (sv)
ES (1) ES467513A1 (sv)
FI (1) FI65252C (sv)
FR (1) FR2383184A1 (sv)
GR (1) GR64160B (sv)
HK (1) HK15084A (sv)
IE (1) IE46478B1 (sv)
IL (1) IL54078A0 (sv)
KE (1) KE3337A (sv)
MX (1) MX4864E (sv)
NL (1) NL7802596A (sv)
NO (1) NO771106L (sv)
SE (1) SE442748B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2862254D1 (en) * 1977-12-02 1983-06-16 Beecham Group Plc A process for the preparation of ether derivatives of clavulanic acid
JPS58187371A (ja) * 1982-04-27 1983-11-01 Nec Corp 印字濃度制御回路
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573503A (en) * 1975-12-17 1980-08-28 Glaxo Lab Ltd Clavulanic acid derivatives

Also Published As

Publication number Publication date
ES467513A1 (es) 1979-08-01
FR2383184A1 (fr) 1978-10-06
IE46478B1 (en) 1983-06-29
FI771146A (fi) 1978-09-11
SE7704085L (sv) 1978-09-11
IE780477L (en) 1978-09-10
KE3337A (en) 1983-11-25
AU3384078A (en) 1979-09-06
AT359188B (de) 1980-10-27
GR64160B (en) 1980-02-05
HK15084A (en) 1984-02-24
MX4864E (es) 1982-11-10
FR2383184B1 (sv) 1980-08-29
IL54078A0 (en) 1978-04-30
AR216505A1 (es) 1979-12-28
ATA145178A (de) 1980-03-15
NO771106L (no) 1978-09-12
FI65252B (fi) 1983-12-30
DK139377A (da) 1978-09-11
DE2808116A1 (de) 1978-09-21
SE442748B (sv) 1986-01-27
JPS53112894A (en) 1978-10-02
NL7802596A (nl) 1978-09-12
FI65252C (fi) 1984-04-10
AU519232B2 (en) 1981-11-19

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PL Patent ceased