FI65252C - Foerfarande foer framstaellning av antibakteriellt och som beta-laktamasinhibitorer verksamma etrar av klavulansyra - Google Patents

Foerfarande foer framstaellning av antibakteriellt och som beta-laktamasinhibitorer verksamma etrar av klavulansyra Download PDF

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Publication number
FI65252C
FI65252C FI771146A FI771146A FI65252C FI 65252 C FI65252 C FI 65252C FI 771146 A FI771146 A FI 771146A FI 771146 A FI771146 A FI 771146A FI 65252 C FI65252 C FI 65252C
Authority
FI
Finland
Prior art keywords
formula
clavulanate
benzyl
ethyl
salt
Prior art date
Application number
FI771146A
Other languages
English (en)
Finnish (fi)
Other versions
FI771146A (fi
FI65252B (fi
Inventor
Thomas Trefor Howarth
Kong Luk
Roger John Ponsford
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB10082/77A external-priority patent/GB1582864A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of FI771146A publication Critical patent/FI771146A/fi
Application granted granted Critical
Publication of FI65252B publication Critical patent/FI65252B/fi
Publication of FI65252C publication Critical patent/FI65252C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI771146A 1977-03-10 1977-04-12 Foerfarande foer framstaellning av antibakteriellt och som beta-laktamasinhibitorer verksamma etrar av klavulansyra FI65252C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB10082/77A GB1582864A (en) 1977-03-10 1977-03-10 Chemical process for the preparation of clavulanic acid derivatives
GB1011677 1977-03-10
GB1011677 1977-03-10
GB1008277 1977-03-10

Publications (3)

Publication Number Publication Date
FI771146A FI771146A (fi) 1978-09-11
FI65252B FI65252B (fi) 1983-12-30
FI65252C true FI65252C (fi) 1984-04-10

Family

ID=26247246

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771146A FI65252C (fi) 1977-03-10 1977-04-12 Foerfarande foer framstaellning av antibakteriellt och som beta-laktamasinhibitorer verksamma etrar av klavulansyra

Country Status (19)

Country Link
JP (1) JPS53112894A (sv)
AR (1) AR216505A1 (sv)
AT (1) AT359188B (sv)
AU (1) AU519232B2 (sv)
CH (1) CH632760A5 (sv)
DE (1) DE2808116A1 (sv)
DK (1) DK139377A (sv)
ES (1) ES467513A1 (sv)
FI (1) FI65252C (sv)
FR (1) FR2383184A1 (sv)
GR (1) GR64160B (sv)
HK (1) HK15084A (sv)
IE (1) IE46478B1 (sv)
IL (1) IL54078A0 (sv)
KE (1) KE3337A (sv)
MX (1) MX4864E (sv)
NL (1) NL7802596A (sv)
NO (1) NO771106L (sv)
SE (1) SE442748B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002370B1 (en) * 1977-12-02 1983-05-11 Beecham Group Plc A process for the preparation of ether derivatives of clavulanic acid
JPS58187371A (ja) * 1982-04-27 1983-11-01 Nec Corp 印字濃度制御回路
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573503A (en) * 1975-12-17 1980-08-28 Glaxo Lab Ltd Clavulanic acid derivatives

Also Published As

Publication number Publication date
FR2383184A1 (fr) 1978-10-06
AU3384078A (en) 1979-09-06
NO771106L (no) 1978-09-12
IE780477L (en) 1978-09-10
DE2808116A1 (de) 1978-09-21
AU519232B2 (en) 1981-11-19
KE3337A (en) 1983-11-25
SE442748B (sv) 1986-01-27
ATA145178A (de) 1980-03-15
FI771146A (fi) 1978-09-11
DK139377A (da) 1978-09-11
SE7704085L (sv) 1978-09-11
JPS53112894A (en) 1978-10-02
FI65252B (fi) 1983-12-30
FR2383184B1 (sv) 1980-08-29
CH632760A5 (en) 1982-10-29
AT359188B (de) 1980-10-27
IL54078A0 (en) 1978-04-30
IE46478B1 (en) 1983-06-29
NL7802596A (nl) 1978-09-12
MX4864E (es) 1982-11-10
HK15084A (en) 1984-02-24
AR216505A1 (es) 1979-12-28
GR64160B (en) 1980-02-05
ES467513A1 (es) 1979-08-01

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Owner name: BEECHAM GROUP LTD