ES467513A1 - Un procedimiento para la preparacion de un compuesto - Google Patents
Un procedimiento para la preparacion de un compuestoInfo
- Publication number
- ES467513A1 ES467513A1 ES467513A ES467513A ES467513A1 ES 467513 A1 ES467513 A1 ES 467513A1 ES 467513 A ES467513 A ES 467513A ES 467513 A ES467513 A ES 467513A ES 467513 A1 ES467513 A1 ES 467513A1
- Authority
- ES
- Spain
- Prior art keywords
- clavulanic
- image
- formula
- group
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Un procedimiento para la preparación de derivados del ácido clavulánico de fórmula (II): **(Fórmula)** donde R1 es un grupo tal que CO2R1 es un grupo éster; R3 es un átomo de hidrógeno o un grupo alquilo de 1 a 4 átomos de carbono; R4 es un átomo de hidrógeno o un grupo alquilo de 1 a 4 átomo de carbono y R5 es un grupo tal que el radical CR3R4R5 es un grupo orgánico inerte de hasta 18 átomos de carbono.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1011677 | 1977-03-10 | ||
GB10082/77A GB1582864A (en) | 1977-03-10 | 1977-03-10 | Chemical process for the preparation of clavulanic acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ES467513A1 true ES467513A1 (es) | 1979-08-01 |
Family
ID=26247246
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES467513A Expired ES467513A1 (es) | 1977-03-10 | 1978-03-02 | Un procedimiento para la preparacion de un compuesto |
Country Status (19)
Country | Link |
---|---|
JP (1) | JPS53112894A (es) |
AR (1) | AR216505A1 (es) |
AT (1) | AT359188B (es) |
AU (1) | AU519232B2 (es) |
CH (1) | CH632760A5 (es) |
DE (1) | DE2808116A1 (es) |
DK (1) | DK139377A (es) |
ES (1) | ES467513A1 (es) |
FI (1) | FI65252C (es) |
FR (1) | FR2383184A1 (es) |
GR (1) | GR64160B (es) |
HK (1) | HK15084A (es) |
IE (1) | IE46478B1 (es) |
IL (1) | IL54078A0 (es) |
KE (1) | KE3337A (es) |
MX (1) | MX4864E (es) |
NL (1) | NL7802596A (es) |
NO (1) | NO771106L (es) |
SE (1) | SE442748B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0002370B1 (en) * | 1977-12-02 | 1983-05-11 | Beecham Group Plc | A process for the preparation of ether derivatives of clavulanic acid |
JPS58187371A (ja) * | 1982-04-27 | 1983-11-01 | Nec Corp | 印字濃度制御回路 |
DE3725375A1 (de) * | 1987-07-31 | 1989-02-09 | Bayer Ag | Stabile oxapenem-3-carbonsaeuren |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1573503A (en) * | 1975-12-17 | 1980-08-28 | Glaxo Lab Ltd | Clavulanic acid derivatives |
-
1977
- 1977-03-29 DK DK139377A patent/DK139377A/da not_active Application Discontinuation
- 1977-03-29 NO NO771106A patent/NO771106L/no unknown
- 1977-04-06 SE SE7704085A patent/SE442748B/xx unknown
- 1977-04-12 FI FI771146A patent/FI65252C/fi not_active IP Right Cessation
-
1978
- 1978-02-20 IL IL54078A patent/IL54078A0/xx unknown
- 1978-02-24 DE DE19782808116 patent/DE2808116A1/de not_active Withdrawn
- 1978-02-27 AR AR271238A patent/AR216505A1/es active
- 1978-03-01 AT AT145178A patent/AT359188B/de not_active IP Right Cessation
- 1978-03-02 ES ES467513A patent/ES467513A1/es not_active Expired
- 1978-03-03 AU AU33840/78A patent/AU519232B2/en not_active Expired
- 1978-03-06 GR GR55621A patent/GR64160B/el unknown
- 1978-03-06 FR FR7806294A patent/FR2383184A1/fr active Granted
- 1978-03-07 JP JP2645178A patent/JPS53112894A/ja active Pending
- 1978-03-08 CH CH252678A patent/CH632760A5/de not_active IP Right Cessation
- 1978-03-09 IE IE477/78A patent/IE46478B1/en unknown
- 1978-03-09 NL NL7802596A patent/NL7802596A/xx not_active Application Discontinuation
- 1978-03-09 MX MX78100818U patent/MX4864E/es unknown
-
1983
- 1983-10-18 KE KE3337A patent/KE3337A/xx unknown
-
1984
- 1984-02-16 HK HK150/84A patent/HK15084A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE2808116A1 (de) | 1978-09-21 |
GR64160B (en) | 1980-02-05 |
AU3384078A (en) | 1979-09-06 |
FI771146A (fi) | 1978-09-11 |
AU519232B2 (en) | 1981-11-19 |
IE46478B1 (en) | 1983-06-29 |
HK15084A (en) | 1984-02-24 |
MX4864E (es) | 1982-11-10 |
FR2383184B1 (es) | 1980-08-29 |
NO771106L (no) | 1978-09-12 |
NL7802596A (nl) | 1978-09-12 |
SE442748B (sv) | 1986-01-27 |
IE780477L (en) | 1978-09-10 |
AR216505A1 (es) | 1979-12-28 |
CH632760A5 (en) | 1982-10-29 |
FR2383184A1 (fr) | 1978-10-06 |
FI65252B (fi) | 1983-12-30 |
JPS53112894A (en) | 1978-10-02 |
IL54078A0 (en) | 1978-04-30 |
ATA145178A (de) | 1980-03-15 |
FI65252C (fi) | 1984-04-10 |
AT359188B (de) | 1980-10-27 |
SE7704085L (sv) | 1978-09-11 |
KE3337A (en) | 1983-11-25 |
DK139377A (da) | 1978-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980202 |