GB2007667A - Process for the Preparation of beta -Lactam Compounds - Google Patents

Process for the Preparation of beta -Lactam Compounds

Info

Publication number
GB2007667A
GB2007667A GB7838666A GB7838666A GB2007667A GB 2007667 A GB2007667 A GB 2007667A GB 7838666 A GB7838666 A GB 7838666A GB 7838666 A GB7838666 A GB 7838666A GB 2007667 A GB2007667 A GB 2007667A
Authority
GB
United Kingdom
Prior art keywords
formula
preparation
group
beta
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7838666A
Other versions
GB2007667B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB7838666A priority Critical patent/GB2007667B/en
Publication of GB2007667A publication Critical patent/GB2007667A/en
Application granted granted Critical
Publication of GB2007667B publication Critical patent/GB2007667B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Abstract

This invention provides a process for the preparation of the compounds of the formula (I> <IMAGE> and esters thereof wherein R1 is an inert organic group of up to 14 carbon atoms and R2 is an inert organic group of up to 16 carbon atoms, the NR1R2 group containing up to 22 carbon atoms, which process comprises the reaction of a compound of the formula (II> <IMAGE> wherein X is Cl, Br or I and A is a group such that CO2A is an ester group with a compound of the formula (III> HNR1R2 (III> wherein R1 and R2 are as defined in relation to formula (I) and thereafter if desired converting the thus formed ester to the acid.
GB7838666A 1977-10-28 1978-09-29 Process for the preparation of ss-lactam compounds Expired GB2007667B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7838666A GB2007667B (en) 1977-10-28 1978-09-29 Process for the preparation of ss-lactam compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4493477 1977-10-28
GB7838666A GB2007667B (en) 1977-10-28 1978-09-29 Process for the preparation of ss-lactam compounds

Publications (2)

Publication Number Publication Date
GB2007667A true GB2007667A (en) 1979-05-23
GB2007667B GB2007667B (en) 1982-05-12

Family

ID=26265481

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7838666A Expired GB2007667B (en) 1977-10-28 1978-09-29 Process for the preparation of ss-lactam compounds

Country Status (1)

Country Link
GB (1) GB2007667B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027324A1 (en) * 1979-09-27 1981-04-22 Beecham Group Plc Derivatives of clavulanic acid, processes for their preparation and pharmaceutical compositions containing them
EP0028083A1 (en) * 1979-10-26 1981-05-06 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0027324A1 (en) * 1979-09-27 1981-04-22 Beecham Group Plc Derivatives of clavulanic acid, processes for their preparation and pharmaceutical compositions containing them
EP0028083A1 (en) * 1979-10-26 1981-05-06 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB2007667B (en) 1982-05-12

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee