SE7908596L - SET TO MAKE SUBSTITUTED PYRROLIESTERS - Google Patents

SET TO MAKE SUBSTITUTED PYRROLIESTERS

Info

Publication number
SE7908596L
SE7908596L SE7908596A SE7908596A SE7908596L SE 7908596 L SE7908596 L SE 7908596L SE 7908596 A SE7908596 A SE 7908596A SE 7908596 A SE7908596 A SE 7908596A SE 7908596 L SE7908596 L SE 7908596L
Authority
SE
Sweden
Prior art keywords
carbon atoms
r1nh2
dicarboxylic acid
substituted
substituted carbonyl
Prior art date
Application number
SE7908596A
Other languages
Swedish (sv)
Inventor
D A Robinson
J C Chen
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of SE7908596L publication Critical patent/SE7908596L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A process for producing a substituted pyrrole of the formula <IMAGE> wherein R1 is a hydrocarbyl group of up to about 20 carbon atoms, R2 and R3 are independently alkyl or aralkyl of up to about 20 carbon atoms and R4 is H or a hydrocarbyl of up to about 20 carbon atoms comprises reacting a primary amine R1NH2 with an acetone dicarboxylic acid diester R3OOCCH2COCH2COR2 and a substituted carbonyl compound R4COCH2X where X is a leaving group. The pyrrole forming reaction is conducted in a two-phase, aqueous/organic reaction medium dispersion containing R1NH2 with which the acetone dicarboxylic acid ester and substituted carbonyl compound are combined and/or in a reaction medium containing R1NH2 to which the acetone dicarboxylic acid ester and substituted carbonyl compounds are added in a substantially simultaneous manner.
SE7908596A 1978-10-19 1979-10-17 SET TO MAKE SUBSTITUTED PYRROLIESTERS SE7908596L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95268278A 1978-10-19 1978-10-19
US95271178A 1978-10-19 1978-10-19

Publications (1)

Publication Number Publication Date
SE7908596L true SE7908596L (en) 1980-04-20

Family

ID=27130329

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7908596A SE7908596L (en) 1978-10-19 1979-10-17 SET TO MAKE SUBSTITUTED PYRROLIESTERS

Country Status (7)

Country Link
CA (1) CA1105039A (en)
DE (1) DE2942140A1 (en)
FI (1) FI793221A (en)
FR (1) FR2439185A1 (en)
GB (1) GB2034304A (en)
NL (1) NL7907735A (en)
SE (1) SE7908596L (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388468A (en) * 1980-04-04 1983-06-14 Ethyl Corporation Process for producing substituted pyrroles
US4565879A (en) * 1980-04-04 1986-01-21 Ethyl Corporation Process for producing substituted pyrroles
US4455433A (en) * 1981-11-02 1984-06-19 Ethyl Corporation Process for producing substituted pyrroles
US4383117A (en) 1981-11-02 1983-05-10 Ethyl Corporation Process for producing substituted pyrroles
IT1151731B (en) * 1982-04-21 1986-12-24 Montedison Spa PROCESS FOR THE PREPARATION OF 3-CARBOXY-1,4-DIMETHYLPIRROL-2-ACETIC ACID
US4835288A (en) * 1987-01-14 1989-05-30 Syntex Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates
US4874872A (en) * 1987-01-14 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4937368A (en) * 1987-01-14 1990-06-26 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles

Also Published As

Publication number Publication date
CA1105039A (en) 1981-07-14
NL7907735A (en) 1980-04-22
DE2942140A1 (en) 1980-04-30
GB2034304A (en) 1980-06-04
FI793221A (en) 1980-04-20
FR2439185A1 (en) 1980-05-16

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