ES454008A1 - Triazole derivatives and processes for the production thereof - Google Patents

Triazole derivatives and processes for the production thereof

Info

Publication number
ES454008A1
ES454008A1 ES454008A ES454008A ES454008A1 ES 454008 A1 ES454008 A1 ES 454008A1 ES 454008 A ES454008 A ES 454008A ES 454008 A ES454008 A ES 454008A ES 454008 A1 ES454008 A1 ES 454008A1
Authority
ES
Spain
Prior art keywords
general formula
lower alkyl
formula
compound
imino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES454008A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES454008A1 publication Critical patent/ES454008A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for obtaining triazole derivatives of the general formula I: ** (See formula) ** where R1 and R2, independent of each other, means hydrogen or hydrocarbon residues with a maximum of 10 carbon atoms in each case, which, as long as it is lower alkyl, can also be linked to each other directly or in the β or γ positio through oxygen, sulfur, the imino moiety or a lower alkyl-imino moiety, R3 means lower alkyl and R4 means hydrogen or lower alkyl, where R3 and R4 as lower alkyl may be linked directly or in the β or γ position also through oxygen, sulfur or the imino moiety or a lower-imino alkyl moiety and the independent A and B rings can be unsubstituted or substituted and of their addition salts with inorganic or organic acids, characterized in that a reactive ester of a compound of general formula II comprised under general formula I, ** (See formula) ** Where R3 and R4 have the meanings indicated under formula I and rings A and B may be substituted as indicated therein, it is reacted with a compound of general formula III ** (See formula) ** where R1 and R2 have the meanings indicated under general formula II, or with an alkali metal derivative of a compound thereof, and, optionally, a triazole derivative of general formula I, obtained is transformed into an addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES454008A 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof Expired ES454008A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH817574A CH601264A5 (en) 1974-06-14 1974-06-14

Publications (1)

Publication Number Publication Date
ES454008A1 true ES454008A1 (en) 1977-11-16

Family

ID=4336312

Family Applications (4)

Application Number Title Priority Date Filing Date
ES438481A Expired ES438481A1 (en) 1974-06-14 1975-06-12 Triazole derivatives and processes for the production thereof
ES454005A Expired ES454005A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454006A Expired ES454006A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454008A Expired ES454008A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES438481A Expired ES438481A1 (en) 1974-06-14 1975-06-12 Triazole derivatives and processes for the production thereof
ES454005A Expired ES454005A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454006A Expired ES454006A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof

Country Status (22)

Country Link
JP (3) JPS6028825B2 (en)
AT (2) AT345821B (en)
AU (1) AU496929B2 (en)
BE (1) BE830214A (en)
CA (1) CA1074313A (en)
CH (1) CH601264A5 (en)
CS (1) CS189712B2 (en)
DE (1) DE2525691A1 (en)
DK (1) DK227075A (en)
DO (1) DOP1980002934A (en)
ES (4) ES438481A1 (en)
FR (1) FR2274302A1 (en)
GB (1) GB1476116A (en)
GT (1) GT198066871A (en)
HK (1) HK49580A (en)
HU (1) HU172467B (en)
IE (1) IE41550B1 (en)
IL (1) IL47474A (en)
MY (1) MY8100158A (en)
NL (1) NL7507104A (en)
SE (1) SE426393B (en)
ZA (1) ZA753809B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5855147B2 (en) * 1976-06-04 1983-12-08 塩野義製薬株式会社 benzophenone derivatives
CN113372215B (en) * 2021-05-20 2024-05-24 吉林大学 Novel esterification method for synthesizing p-halomethyl benzoate
WO2023052312A1 (en) 2021-09-29 2023-04-06 F. Hoffmann-La Roche Ag New benzodiazepine derivatives as gaba a gamma1 pam

Also Published As

Publication number Publication date
JPS617424B2 (en) 1986-03-06
FR2274302B1 (en) 1979-08-17
HU172467B (en) 1978-09-28
SE7505952L (en) 1975-12-15
ES454006A1 (en) 1977-11-16
JPS59130279A (en) 1984-07-26
ATA455875A (en) 1978-02-15
AT345822B (en) 1978-10-10
CH601264A5 (en) 1978-06-30
AT345821B (en) 1978-10-10
DE2525691A1 (en) 1976-01-02
IL47474A (en) 1980-01-31
BE830214A (en) 1975-12-15
ES438481A1 (en) 1977-06-16
IE41550L (en) 1975-12-14
GT198066871A (en) 1982-06-05
DOP1980002934A (en) 1986-02-14
NL7507104A (en) 1975-12-16
CA1074313A (en) 1980-03-25
MY8100158A (en) 1981-12-31
ZA753809B (en) 1976-05-26
GB1476116A (en) 1977-06-10
SE426393B (en) 1983-01-17
DK227075A (en) 1975-12-15
JPS6021984B2 (en) 1985-05-30
JPS59108770A (en) 1984-06-23
AU496929B2 (en) 1978-11-09
AU8208275A (en) 1976-12-16
JPS6028825B2 (en) 1985-07-06
HK49580A (en) 1980-09-12
FR2274302A1 (en) 1976-01-09
IE41550B1 (en) 1980-01-30
ATA498877A (en) 1978-02-15
IL47474A0 (en) 1975-08-31
CS189712B2 (en) 1979-04-30
ES454005A1 (en) 1977-11-16
JPS5111768A (en) 1976-01-30

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