ES405048A1 - Phenothiazine derivatives - Google Patents

Phenothiazine derivatives

Info

Publication number
ES405048A1
ES405048A1 ES405048A ES405048A ES405048A1 ES 405048 A1 ES405048 A1 ES 405048A1 ES 405048 A ES405048 A ES 405048A ES 405048 A ES405048 A ES 405048A ES 405048 A1 ES405048 A1 ES 405048A1
Authority
ES
Spain
Prior art keywords
radical
general formula
carbon atoms
hydrogen atom
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES405048A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of ES405048A1 publication Critical patent/ES405048A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for obtaining phenothiazine derivatives of general formula: ** (See formula) ** where X represents a methylsulfonyl radical or a dimethylsulfamoyl radical, A represents a radical - (CH2) 3-O-CH2-CH (CH3) -CH2-, R1 represents a hydrogen atom or an alkyl radical containing from 1 to 4 carbon atoms, R represents a hydrogen atom and B represents a straight or branched alkylene radical containing from 2 to 5 carbon atoms, as well as their addition salts with acids, characterized in that a derivative of the phenothiazine of general formula: ** (See formula) ** in which X and A have the aforementioned meaning and Y represents a reactive ester residue, on a piperidine of general formula: ** (See formula) ** wherein R1 and B are defined as above, and then the product obtained is optionally transformed into an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES405048A 1971-07-21 1972-07-21 Phenothiazine derivatives Expired ES405048A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7126709A FR2146150B1 (en) 1971-07-21 1971-07-21

Publications (1)

Publication Number Publication Date
ES405048A1 true ES405048A1 (en) 1975-07-16

Family

ID=9080680

Family Applications (2)

Application Number Title Priority Date Filing Date
ES405048A Expired ES405048A1 (en) 1971-07-21 1972-07-21 Phenothiazine derivatives
ES407867A Expired ES407867A1 (en) 1971-07-21 1972-10-23 Phenothiazine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES407867A Expired ES407867A1 (en) 1971-07-21 1972-10-23 Phenothiazine derivatives

Country Status (11)

Country Link
JP (1) JPS5619349B1 (en)
AR (2) AR193118A1 (en)
AT (1) AT317234B (en)
AU (1) AU458571B2 (en)
BE (1) BE786583A (en)
CH (1) CH541578A (en)
DE (1) DE2235998C3 (en)
ES (2) ES405048A1 (en)
FR (1) FR2146150B1 (en)
GB (1) GB1333700A (en)
NL (1) NL7209698A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104884064A (en) 2012-12-24 2015-09-02 纽洛佳斯特拉斯公司 Methods for treating gi tract disorders
US9844554B2 (en) * 2014-06-24 2017-12-19 Neurogastrx, Inc. Prodrugs of metopimazine
US10836757B1 (en) 2020-04-02 2020-11-17 Neurogastrx, Inc. Polymorphic forms of metopimazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL99690C (en) * 1956-11-15
DE1092476B (en) * 1958-04-24 1960-11-10 Rhone Poulenc Sa Process for the preparation of phenthiazine derivatives

Also Published As

Publication number Publication date
DE2235998C3 (en) 1982-01-07
BE786583A (en) 1973-01-22
JPS5619349B1 (en) 1981-05-07
FR2146150A1 (en) 1973-03-02
DE2235998B2 (en) 1981-04-02
CH541578A (en) 1973-09-15
DE2235998A1 (en) 1973-02-01
AR193181A1 (en) 1973-03-30
GB1333700A (en) 1973-10-10
FR2146150B1 (en) 1974-09-06
AT317234B (en) 1974-08-26
AU4474172A (en) 1974-01-24
AR193118A1 (en) 1973-03-30
ES407867A1 (en) 1975-11-16
NL7209698A (en) 1973-01-23
AU458571B2 (en) 1975-02-27

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