ES438481A1 - Triazole derivatives and processes for the production thereof - Google Patents

Triazole derivatives and processes for the production thereof

Info

Publication number
ES438481A1
ES438481A1 ES438481A ES438481A ES438481A1 ES 438481 A1 ES438481 A1 ES 438481A1 ES 438481 A ES438481 A ES 438481A ES 438481 A ES438481 A ES 438481A ES 438481 A1 ES438481 A1 ES 438481A1
Authority
ES
Spain
Prior art keywords
lower alkyl
formula
general formula
substituted
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES438481A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Priority to ES454150A priority Critical patent/ES454150A2/en
Publication of ES438481A1 publication Critical patent/ES438481A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for obtaining triazole derivatives of general formula I, **(See formula)** where R1 signifies hydrogen, lower alkyl, hydroxymethyl, optionally esterified or ethereal, fornyl, carboxy, optionally functionally modified or aminomethyl, optionally mono- or substituted, R2 signifies lower alkyl and means hydrogen or lower alkyl, where R2 may and R3 as lower alkyl, be linked directly or in the β γ position or also through oxygen, sulfur, or the imino moiety or a lower alkyl-imino moiety, and rings A and B, independent of each other, may be instituted or substituted, and their addition salts with inorganic and organic acids, characterized WHY a reactive ester of a compound of general formula II **(See formula)** where R1 has the meaning indicated under formula I and rings A and B may be substituted as indicated therein, reacted with a compound of general formula III, **(See formula)** where R2 and R3 have the meanings indicated under formula I, or with an alkali metal derivative of a compound thereof with R3 other than hydrogen, and, if desired, a triazole derivative of general formula I, obtained is transformed into an addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES438481A 1974-06-14 1975-06-12 Triazole derivatives and processes for the production thereof Expired ES438481A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES454150A ES454150A2 (en) 1975-06-12 1976-12-10 Procedure for the obtaining of triazol derivatives. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH817574A CH601264A5 (en) 1974-06-14 1974-06-14

Publications (1)

Publication Number Publication Date
ES438481A1 true ES438481A1 (en) 1977-06-16

Family

ID=4336312

Family Applications (4)

Application Number Title Priority Date Filing Date
ES438481A Expired ES438481A1 (en) 1974-06-14 1975-06-12 Triazole derivatives and processes for the production thereof
ES454005A Expired ES454005A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454006A Expired ES454006A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454008A Expired ES454008A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES454005A Expired ES454005A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454006A Expired ES454006A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof
ES454008A Expired ES454008A1 (en) 1974-06-14 1976-12-06 Triazole derivatives and processes for the production thereof

Country Status (22)

Country Link
JP (3) JPS6028825B2 (en)
AT (2) AT345821B (en)
AU (1) AU496929B2 (en)
BE (1) BE830214A (en)
CA (1) CA1074313A (en)
CH (1) CH601264A5 (en)
CS (1) CS189712B2 (en)
DE (1) DE2525691A1 (en)
DK (1) DK227075A (en)
DO (1) DOP1980002934A (en)
ES (4) ES438481A1 (en)
FR (1) FR2274302A1 (en)
GB (1) GB1476116A (en)
GT (1) GT198066871A (en)
HK (1) HK49580A (en)
HU (1) HU172467B (en)
IE (1) IE41550B1 (en)
IL (1) IL47474A (en)
MY (1) MY8100158A (en)
NL (1) NL7507104A (en)
SE (1) SE426393B (en)
ZA (1) ZA753809B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5855147B2 (en) * 1976-06-04 1983-12-08 塩野義製薬株式会社 benzophenone derivatives
CN113372215B (en) * 2021-05-20 2024-05-24 吉林大学 Novel esterification method for synthesizing p-halomethyl benzoate
JP2024537773A (en) 2021-09-29 2024-10-16 エフ. ホフマン-ラ ロシュ アーゲー Novel benzodiazepine derivatives as GABA Aγ1 PAMs

Also Published As

Publication number Publication date
BE830214A (en) 1975-12-15
FR2274302A1 (en) 1976-01-09
DOP1980002934A (en) 1986-02-14
ZA753809B (en) 1976-05-26
HU172467B (en) 1978-09-28
CS189712B2 (en) 1979-04-30
GT198066871A (en) 1982-06-05
ES454005A1 (en) 1977-11-16
ES454006A1 (en) 1977-11-16
MY8100158A (en) 1981-12-31
JPS5111768A (en) 1976-01-30
AT345821B (en) 1978-10-10
DE2525691A1 (en) 1976-01-02
AU496929B2 (en) 1978-11-09
JPS6028825B2 (en) 1985-07-06
CA1074313A (en) 1980-03-25
IL47474A0 (en) 1975-08-31
FR2274302B1 (en) 1979-08-17
IE41550B1 (en) 1980-01-30
JPS6021984B2 (en) 1985-05-30
AT345822B (en) 1978-10-10
ES454008A1 (en) 1977-11-16
ATA455875A (en) 1978-02-15
ATA498877A (en) 1978-02-15
JPS59108770A (en) 1984-06-23
HK49580A (en) 1980-09-12
AU8208275A (en) 1976-12-16
JPS59130279A (en) 1984-07-26
GB1476116A (en) 1977-06-10
IL47474A (en) 1980-01-31
SE426393B (en) 1983-01-17
IE41550L (en) 1975-12-14
CH601264A5 (en) 1978-06-30
DK227075A (en) 1975-12-15
JPS617424B2 (en) 1986-03-06
SE7505952L (en) 1975-12-15
NL7507104A (en) 1975-12-16

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