CH631449A5 - Forme cristalline nouvelle de l'agent antiinflammatoire : acide 2-(4-chlorophenyl-alpha-methyl-5-benzoxazolylacetique, procede pour sa preparation et application comme medicaments. - Google Patents

Forme cristalline nouvelle de l'agent antiinflammatoire : acide 2-(4-chlorophenyl-alpha-methyl-5-benzoxazolylacetique, procede pour sa preparation et application comme medicaments. Download PDF

Info

Publication number
CH631449A5
CH631449A5 CH691778A CH691778A CH631449A5 CH 631449 A5 CH631449 A5 CH 631449A5 CH 691778 A CH691778 A CH 691778A CH 691778 A CH691778 A CH 691778A CH 631449 A5 CH631449 A5 CH 631449A5
Authority
CH
Switzerland
Prior art keywords
methyl
chlorophenyl
acid
benzoxazolylacetic
benoxaprofen
Prior art date
Application number
CH691778A
Other languages
English (en)
French (fr)
Inventor
Roy Sherlock
Terence Alan Hicks
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of CH631449A5 publication Critical patent/CH631449A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH691778A 1977-06-28 1978-06-26 Forme cristalline nouvelle de l'agent antiinflammatoire : acide 2-(4-chlorophenyl-alpha-methyl-5-benzoxazolylacetique, procede pour sa preparation et application comme medicaments. CH631449A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB26907/77A GB1590587A (en) 1977-06-28 1977-06-28 Benoxaprofen

Publications (1)

Publication Number Publication Date
CH631449A5 true CH631449A5 (fr) 1982-08-13

Family

ID=10251100

Family Applications (1)

Application Number Title Priority Date Filing Date
CH691778A CH631449A5 (fr) 1977-06-28 1978-06-26 Forme cristalline nouvelle de l'agent antiinflammatoire : acide 2-(4-chlorophenyl-alpha-methyl-5-benzoxazolylacetique, procede pour sa preparation et application comme medicaments.

Country Status (17)

Country Link
EP (1) EP0000276B1 (it)
JP (1) JPS5411224A (it)
AT (1) AT360008B (it)
AU (1) AU518403B2 (it)
BE (1) BE868522A (it)
CH (1) CH631449A5 (it)
DE (2) DE2828074A1 (it)
DK (1) DK145419C (it)
FI (1) FI69453C (it)
FR (1) FR2396004A1 (it)
GB (1) GB1590587A (it)
IE (1) IE47009B1 (it)
IL (1) IL55015A (it)
IT (1) IT1105065B (it)
LU (1) LU79879A1 (it)
NZ (1) NZ187674A (it)
ZA (1) ZA783660B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11981645B1 (en) 2023-10-10 2024-05-14 King Faisal University N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1435721A (en) * 1972-05-18 1976-05-12 Lilly Industries Ltd Benzoxazole derivatives
US3888864A (en) 1973-06-29 1975-06-10 Hoffmann La Roche Amino lower alkyl ether derivatives of opium alkaloids
GB1495488A (en) * 1976-06-23 1977-12-21 Ippco Int Pharma Patents Co Es Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids
IT1099589B (it) * 1978-08-04 1985-09-18 Ravizza Spa Processo per la preparazione di derivati dell'acido benzoxazolil propionico
IT1157295B (it) * 1982-07-19 1987-02-11 Ravizza Spa Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico
UA83620C2 (ru) 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
WO2021116820A1 (en) * 2019-12-10 2021-06-17 Aurobindo Pharma Limited An improved process for the preparation of benoxaprofen
DE102022117931A1 (de) 2022-07-18 2024-01-18 HUECK System GmbH & Co. KG Profilanordnung mit wärmedämmung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1435721A (en) * 1972-05-18 1976-05-12 Lilly Industries Ltd Benzoxazole derivatives
GB1488003A (en) * 1973-10-23 1977-10-05 Lilly Industries Ltd 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals
US4087437A (en) * 1976-09-07 1978-05-02 Eli Lilly And Company 2-Phenyl-5-benzoxazolylalkanoic acid purification process

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11981645B1 (en) 2023-10-10 2024-05-14 King Faisal University N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound

Also Published As

Publication number Publication date
IL55015A0 (en) 1978-08-31
IL55015A (en) 1981-11-30
ZA783660B (en) 1979-06-27
IE47009B1 (en) 1983-11-30
FR2396004B1 (it) 1981-09-18
LU79879A1 (it) 1978-12-07
DE2828074A1 (de) 1979-01-11
FR2396004A1 (fr) 1979-01-26
DE2862013D1 (en) 1982-10-28
AU518403B2 (en) 1981-10-01
AU3750178A (en) 1980-01-03
AT360008B (de) 1980-12-10
GB1590587A (en) 1981-06-03
IE781277L (en) 1978-12-28
JPS5411224A (en) 1979-01-27
DK287578A (da) 1978-12-29
EP0000276B1 (en) 1982-09-01
FI69453B (fi) 1985-10-31
ATA466178A (de) 1980-05-15
DK145419B (da) 1982-11-15
JPS6231714B2 (it) 1987-07-09
IT1105065B (it) 1985-10-28
FI782043A (fi) 1978-12-29
FI69453C (fi) 1986-02-10
NZ187674A (en) 1980-11-14
BE868522A (fr) 1978-12-27
IT7850048A0 (it) 1978-06-27
EP0000276A1 (en) 1979-01-10
DK145419C (da) 1983-04-18

Similar Documents

Publication Publication Date Title
EP0162036B1 (fr) (S)-alpha-éthyl-2-oxo-1-pyrrolidineacétamide
CH643546A5 (fr) Procede pour la preparation de derives d'hydantoine.
CA2599637A1 (fr) Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl)-1,2,3,6-tetrahydro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique
CH631449A5 (fr) Forme cristalline nouvelle de l'agent antiinflammatoire : acide 2-(4-chlorophenyl-alpha-methyl-5-benzoxazolylacetique, procede pour sa preparation et application comme medicaments.
EP2612850B1 (fr) Forme cristalline delta du sel d'arginine du périndopril, son procédé de préparation, et les compositions pharmaceutiques qui la contiennent
LU82105A1 (fr) Trans-5-aryl-2,3,4,4a-5-9b-hexahydro-1h-pyrido(4,3-b)indoles substitues en position 2 dextrogyres, procedes et composes intermediaires permettant de les obtenir et composition pharmaceutique les contenant
CA1097647A (fr) Procede de preparation de nouvelles imidazoquinoleines et de leurs sels
EP0349432B1 (fr) Sel de strontium, son procédé de préparation et les compositions pharmaceutiques le renfermant
RU2178413C2 (ru) Способ получения 3-амино-1,2,4-бензотриазин-1,4-диоксида (варианты)
CH594650A5 (en) Antiinflammatory (1,2)-benzothiazine derivs. prepn.
Caldwell et al. The Synthesis of 4-Chloromethylthiazole Hydrochloride and β-(4-Thiazolyl)-alanine Hydrochloride1
US4507482A (en) Purification of mefloquin hydrochloride
CH439271A (fr) Procédé de préparation de nouvelles 4-dédiméthylamino-4-amino substitué-6-déméthyl-tétracyclines
CH627473A5 (fr) Procede de preparation de nouveaux derives thiazoliques.
CA2122584A1 (en) A process for the resolution of (+-)-.alpha.-[2-[acetyl(1-methylethyl)amino]ethyl]-.alpha.-(2-chlorophenyl)-1-piperidinebutanamide
CH645115A5 (fr) Procede pour preparer la chloro-7 methyl-2 dihydro-3,3a 2h,9h-isoxazolo(3,2-b)(benzoxazine-1,3)one-9.
CA2325629C (fr) Formes cristallines du 1s-[1alpha (2s*,3r*),9alpha]-6, 10-dioxo-n- (2-ethoxy-5 -oxo-tetrahydro-3 -furanyl) -9-[[(1-isoquinolyl) carbonyl]-amino] octahydro-6h -piridazino[1, 2-a][1,2] diazepine-1- carboxamide
FR2653999A1 (fr) Nouveaux derives de la morpholine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2459241A1 (fr) Nouveaux pyridylaminotriazoles et composition pharmaceutique les contenant
FI69454B (fi) Saett att framstaella en termodynamiskt stabil ny polymorf form av terapeutiskt anvaendbar 2-(4-klorfenyl)-alfa-metyl-5-bensoxazolylaettiksyra
EP0005422A2 (fr) Dérivés d'acides oméga-dialkylalkanoiques, leurs procédés de préparation ainsi que leur utilisation en thérapeutique
FR2508448A1 (fr) Monohydrate de cimetidine et procede pour sa preparation
BE824491R (fr) Procede de preparation de derives de 1,8-naphthyridine
OA16425A (fr) Forme cristalline delta du sel d'arginine du périndopril, son procédé de préparation, et les compositions pharmaceutiques qui la contiennent.
EP1348703A1 (fr) Formes polymorphes du fasidotril, leurs procédés de préparation et compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
PL Patent ceased