CH629493A5 - Processes for preparing novel prostaglandin derivatives - Google Patents

Processes for preparing novel prostaglandin derivatives Download PDF

Info

Publication number
CH629493A5
CH629493A5 CH583677A CH583677A CH629493A5 CH 629493 A5 CH629493 A5 CH 629493A5 CH 583677 A CH583677 A CH 583677A CH 583677 A CH583677 A CH 583677A CH 629493 A5 CH629493 A5 CH 629493A5
Authority
CH
Switzerland
Prior art keywords
formula
compound
epoxyprostaglandin
deoxy
fia
Prior art date
Application number
CH583677A
Other languages
German (de)
English (en)
Inventor
Salvador Moncada
Norman Whittaker
Harry Tacon Openshaw
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1938676A external-priority patent/GB1583962A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of CH629493A5 publication Critical patent/CH629493A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH583677A 1976-05-11 1977-05-10 Processes for preparing novel prostaglandin derivatives CH629493A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1938676A GB1583962A (en) 1976-05-11 1976-05-11 Prostacyclin derivatives
GB3415376 1976-08-17
GB1338977 1977-03-30

Publications (1)

Publication Number Publication Date
CH629493A5 true CH629493A5 (en) 1982-04-30

Family

ID=27256987

Family Applications (1)

Application Number Title Priority Date Filing Date
CH583677A CH629493A5 (en) 1976-05-11 1977-05-10 Processes for preparing novel prostaglandin derivatives

Country Status (6)

Country Link
JP (1) JPS537665A (enrdf_load_stackoverflow)
CH (1) CH629493A5 (enrdf_load_stackoverflow)
DE (1) DE2720998A1 (enrdf_load_stackoverflow)
FR (1) FR2351113A1 (enrdf_load_stackoverflow)
IT (1) IT1079025B (enrdf_load_stackoverflow)
NL (1) NL7705143A (enrdf_load_stackoverflow)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
MX4813E (es) * 1976-06-01 1982-10-19 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
DE3035713A1 (de) * 1980-09-22 1982-04-29 F. Hoffmann-La Roche & Co. AG, 4002 Basel Prostacycline

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs

Also Published As

Publication number Publication date
DE2720998A1 (de) 1977-11-24
DE2720998C2 (enrdf_load_stackoverflow) 1989-04-06
JPS6112909B2 (enrdf_load_stackoverflow) 1986-04-10
FR2351113B1 (enrdf_load_stackoverflow) 1981-01-02
IT1079025B (it) 1985-05-08
JPS537665A (en) 1978-01-24
FR2351113A1 (fr) 1977-12-09
NL7705143A (nl) 1977-11-15

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Legal Events

Date Code Title Description
PL Patent ceased