CH626370A5 - Process for the preparation of the syn isomer or of a mixture of syn and anti isomers of 7beta-acylamidoceph-3-em-4-carboxylic acids with antibiotic activity - Google Patents

Process for the preparation of the syn isomer or of a mixture of syn and anti isomers of 7beta-acylamidoceph-3-em-4-carboxylic acids with antibiotic activity Download PDF

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Publication number
CH626370A5
CH626370A5 CH449880A CH449880A CH626370A5 CH 626370 A5 CH626370 A5 CH 626370A5 CH 449880 A CH449880 A CH 449880A CH 449880 A CH449880 A CH 449880A CH 626370 A5 CH626370 A5 CH 626370A5
Authority
CH
Switzerland
Prior art keywords
syn
isomer
formula
compounds
fur
Prior art date
Application number
CH449880A
Other languages
German (de)
English (en)
Inventor
Janice Bradshaw
Martin Christopher Cook
Gordon Ian Gregory
Original Assignee
Glaxo Operations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Operations Ltd filed Critical Glaxo Operations Ltd
Publication of CH626370A5 publication Critical patent/CH626370A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH449880A 1973-12-21 1980-06-11 Process for the preparation of the syn isomer or of a mixture of syn and anti isomers of 7beta-acylamidoceph-3-em-4-carboxylic acids with antibiotic activity CH626370A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB59517/73A GB1496757A (en) 1973-12-21 1973-12-21 Cephalosporin derivatives

Publications (1)

Publication Number Publication Date
CH626370A5 true CH626370A5 (en) 1981-11-13

Family

ID=10483908

Family Applications (1)

Application Number Title Priority Date Filing Date
CH449880A CH626370A5 (en) 1973-12-21 1980-06-11 Process for the preparation of the syn isomer or of a mixture of syn and anti isomers of 7beta-acylamidoceph-3-em-4-carboxylic acids with antibiotic activity

Country Status (8)

Country Link
JP (1) JPS5655392A (fr)
BE (1) BE823651A (fr)
CA (1) CA1059991A (fr)
CH (1) CH626370A5 (fr)
FR (1) FR2355849A1 (fr)
GB (1) GB1496757A (fr)
PH (1) PH11646A (fr)
ZA (1) ZA748146B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO760358L (fr) * 1975-02-04 1976-08-05 Fujisawa Pharmaceutical Co
AR229883A1 (es) 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
CA1130280A (fr) * 1978-10-27 1982-08-24 Cynthia H. O'callaghan Cephalosporines
IL58717A (en) * 1978-11-15 1983-05-15 Glaxo Group Ltd Derivatives of(6r,7r)-7-((z)-2-(2-aminothiazol-4-yl)-2-(carboxy-(lower alkyl or cycloalkyl)oxyimino)acetamido)-3-(2-alkyl-pyrazolium-1-ylmethyl)ceph-3-em-4-carboxylate,process for their preparation and pharmaceutical compositions comprising them
ZA877987B (en) * 1986-11-12 1988-08-31 Ici Pharma Antibiotic compounds
US5262410A (en) * 1986-12-23 1993-11-16 Ici Pharma 3-heterocyclic thiomethyl cephalosporins
EP0272827A3 (fr) * 1986-12-23 1990-02-07 ZENECA Pharma S.A. 3-Hétérocycliquethiométhyl céphalosporines
US20040166434A1 (en) 2003-02-21 2004-08-26 Dammel Ralph R. Photoresist composition for deep ultraviolet lithography
WO2009073620A2 (fr) 2007-11-30 2009-06-11 Newlink Genetics Inhibiteurs de l'ido

Also Published As

Publication number Publication date
BE823651A (fr) 1975-06-20
CA1059991A (fr) 1979-08-07
PH11646A (en) 1978-05-08
JPS5655392A (en) 1981-05-15
FR2355849A1 (fr) 1978-01-20
ZA748146B (en) 1976-01-28
GB1496757A (en) 1978-01-05
FR2355849B1 (fr) 1980-10-17

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PL Patent ceased