CH621330A5 - - Google Patents

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Publication number
CH621330A5
CH621330A5 CH606376A CH606376A CH621330A5 CH 621330 A5 CH621330 A5 CH 621330A5 CH 606376 A CH606376 A CH 606376A CH 606376 A CH606376 A CH 606376A CH 621330 A5 CH621330 A5 CH 621330A5
Authority
CH
Switzerland
Prior art keywords
carbon atoms
formula
alkyl
compounds
substituted
Prior art date
Application number
CH606376A
Other languages
German (de)
English (en)
Inventor
Richard Dr Berthold
Trevor Glyn Dr Payne
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to CH606376A priority Critical patent/CH621330A5/de
Priority to DE19772719871 priority patent/DE2719871A1/de
Priority to SE7705221A priority patent/SE7705221L/xx
Priority to FI771427A priority patent/FI771427A/fi
Priority to DK197677A priority patent/DK197677A/da
Priority to GB19551/77A priority patent/GB1576034A/en
Priority to NL7705128A priority patent/NL7705128A/xx
Priority to US05/795,439 priority patent/US4322437A/en
Priority to CY1226A priority patent/CY1226A/xx
Priority to ES77458724A priority patent/ES458724A1/es
Priority to FR7714506A priority patent/FR2351091A1/fr
Priority to IL52072A priority patent/IL52072A/xx
Priority to NZ184079A priority patent/NZ184079A/xx
Priority to CA278,293A priority patent/CA1095913A/en
Priority to IE971/77A priority patent/IE44950B1/en
Priority to BE177524A priority patent/BE854567A/xx
Priority to PT66540A priority patent/PT66540B/pt
Priority to AT343577A priority patent/AT362349B/de
Priority to JP5449177A priority patent/JPS52139051A/ja
Priority to AU25140/77A priority patent/AU513066B2/en
Priority to PH19769A priority patent/PH14176A/en
Priority to ZA00772873A priority patent/ZA772873B/xx
Priority to SU772480276A priority patent/SU634663A3/ru
Publication of CH621330A5 publication Critical patent/CH621330A5/de
Priority to SG849/83A priority patent/SG84983G/en
Priority to KE3405A priority patent/KE3405A/xx
Priority to HK359/84A priority patent/HK35984A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/38—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/93—Spiro compounds
    • C07C2603/94—Spiro compounds containing "free" spiro atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH606376A 1976-05-14 1976-05-14 CH621330A5 (ja)

Priority Applications (26)

Application Number Priority Date Filing Date Title
CH606376A CH621330A5 (ja) 1976-05-14 1976-05-14
DE19772719871 DE2719871A1 (de) 1976-05-14 1977-05-04 Substituierte 3-amino-2-hydroxypropoxyphenyl-derivate, ihre verwendung und herstellung
SE7705221A SE7705221L (sv) 1976-05-14 1977-05-05 Organiska foreningar, deras anvendning och framstellning
FI771427A FI771427A (ja) 1976-05-14 1977-05-05
DK197677A DK197677A (da) 1976-05-14 1977-05-05 Fremgangsmade til fremstilling af substituerede 1-amino-2-hydroxypropoxyderivater
GB19551/77A GB1576034A (en) 1976-05-14 1977-05-10 Spirocyclic compounds
NL7705128A NL7705128A (nl) 1976-05-14 1977-05-10 Werkwijze voor het bereiden en toepassen van aromatische verbindingen.
US05/795,439 US4322437A (en) 1976-05-14 1977-05-10 Spiro substituted indanones and tetralones
CY1226A CY1226A (en) 1976-05-14 1977-05-10 Spirocyclic compounds
CA278,293A CA1095913A (en) 1976-05-14 1977-05-12 3-amino-2-hydroxypropoxyphenyl derivatives
FR7714506A FR2351091A1 (fr) 1976-05-14 1977-05-12 Nouveaux derives du propyleneglycol, leur preparation et leur application comme medicaments
IL52072A IL52072A (en) 1976-05-14 1977-05-12 4-(or5)-(3-(substituted amino)-2-hydroxypropoxy)-spiro cycloalkane indanone or naphthone derivatives,their preparation and pharmaceutical compositions coprising them
NZ184079A NZ184079A (en) 1976-05-14 1977-05-12 3-(substituted amino)-2-hydroxypropoxy derivatives of spiro compounds and pharmaceutical compositions
ES77458724A ES458724A1 (es) 1976-05-14 1977-05-12 Procedimiento para la produccion de derivados de 3-amino-2- hidroxi-propoxifenilo.
IE971/77A IE44950B1 (en) 1976-05-14 1977-05-12 Improvements in or relating to spirocyclic compounds
BE177524A BE854567A (fr) 1976-05-14 1977-05-12 Nouveaux derives du propyleneglycol
PT66540A PT66540B (fr) 1976-05-14 1977-05-12 Procede pour la preparation de nouveaux composes organiques a effect pharmaceutique
JP5449177A JPS52139051A (en) 1976-05-14 1977-05-13 Improvement of organic compound
AT343577A AT362349B (de) 1976-05-14 1977-05-13 Verfahren zur herstellung von neuen 3-amino-2- -hydroxypropoxyaryl-derivaten
AU25140/77A AU513066B2 (en) 1976-05-14 1977-05-13 3 amino-2hydroxy-propoxphenyl derivatives
PH19769A PH14176A (en) 1976-05-14 1977-05-13 3-amino-2-hydroxypropyl derivative
ZA00772873A ZA772873B (en) 1976-05-14 1977-05-13 Improvements in or relating to organic compounds
SU772480276A SU634663A3 (ru) 1976-05-14 1977-05-13 Способ получени производных индана или их солей, рацематов или оптическиактивных антиподов
SG849/83A SG84983G (en) 1976-05-14 1983-12-29 Improvements in or relating to spirocyclic compounds
KE3405A KE3405A (en) 1976-05-14 1984-04-19 Improvements in or relating to spirocyclic compounds
HK359/84A HK35984A (en) 1976-05-14 1984-04-26 Improvements in or relating to spirocyclic compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH606376A CH621330A5 (ja) 1976-05-14 1976-05-14

Publications (1)

Publication Number Publication Date
CH621330A5 true CH621330A5 (ja) 1981-01-30

Family

ID=4303639

Family Applications (1)

Application Number Title Priority Date Filing Date
CH606376A CH621330A5 (ja) 1976-05-14 1976-05-14

Country Status (26)

Country Link
US (1) US4322437A (ja)
JP (1) JPS52139051A (ja)
AT (1) AT362349B (ja)
AU (1) AU513066B2 (ja)
BE (1) BE854567A (ja)
CA (1) CA1095913A (ja)
CH (1) CH621330A5 (ja)
CY (1) CY1226A (ja)
DE (1) DE2719871A1 (ja)
DK (1) DK197677A (ja)
ES (1) ES458724A1 (ja)
FI (1) FI771427A (ja)
FR (1) FR2351091A1 (ja)
GB (1) GB1576034A (ja)
HK (1) HK35984A (ja)
IE (1) IE44950B1 (ja)
IL (1) IL52072A (ja)
KE (1) KE3405A (ja)
NL (1) NL7705128A (ja)
NZ (1) NZ184079A (ja)
PH (1) PH14176A (ja)
PT (1) PT66540B (ja)
SE (1) SE7705221L (ja)
SG (1) SG84983G (ja)
SU (1) SU634663A3 (ja)
ZA (1) ZA772873B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2810869A1 (de) * 1977-03-24 1978-09-28 Sandoz Ag 3-amino-2-hydroxypropoxy-derivate, ihre herstellung und verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2641152A (en) * 1949-07-15 1953-06-09 Herbert M Hise Stringed musical instrument
GB1046001A (en) * 1964-03-12 1966-10-19 Ici Ltd Propanolamine derivatives
US3839415A (en) * 1965-10-22 1974-10-01 Lilly Co Eli 2-halo-1-(alkyl-1-(alkylamino)ethyl)vinyl benzoic acid esters and derivatives
US3641152A (en) * 1968-09-23 1972-02-08 Warner Lambert Pharmaceutical 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines
CH554314A (de) * 1969-06-03 1974-09-30 Sandoz Ag Verfahren zur herstellung neuer fluorenone.
BE755071A (fr) * 1969-09-17 1971-02-22 Warner Lambert Pharmaceutical Procede de resolution de la dl-5-/3-(terbutylamino)-2- hydroxy-propoxy/-3,4-dihydro-1(2h) naphtalenone

Also Published As

Publication number Publication date
FI771427A (ja) 1977-11-15
AU513066B2 (en) 1980-11-13
PH14176A (en) 1981-03-19
IE44950L (en) 1977-11-14
JPS52139051A (en) 1977-11-19
IL52072A (en) 1980-10-26
SE7705221L (sv) 1977-11-15
SU634663A3 (ru) 1978-11-25
HK35984A (en) 1984-05-04
GB1576034A (en) 1980-10-01
CA1095913A (en) 1981-02-17
PT66540B (fr) 1979-10-22
AU2514077A (en) 1978-11-16
CY1226A (en) 1984-04-06
IL52072A0 (en) 1977-07-31
NZ184079A (en) 1978-09-25
DK197677A (da) 1977-11-15
ATA343577A (de) 1980-10-15
BE854567A (fr) 1977-11-14
FR2351091A1 (fr) 1977-12-09
ZA772873B (en) 1978-12-27
US4322437A (en) 1982-03-30
KE3405A (en) 1985-02-01
IE44950B1 (en) 1982-05-19
FR2351091B1 (ja) 1980-01-18
AT362349B (de) 1981-05-11
SG84983G (en) 1985-01-11
NL7705128A (nl) 1977-11-16
PT66540A (fr) 1977-06-01
DE2719871A1 (de) 1977-12-01
ES458724A1 (es) 1978-08-01

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Date Code Title Description
PL Patent ceased