CH615442A5 - Process for the preparation of 17alpha,21-diesters of 17alpha,21-dihydroxysteroids of the pregnane series - Google Patents
Process for the preparation of 17alpha,21-diesters of 17alpha,21-dihydroxysteroids of the pregnane series Download PDFInfo
- Publication number
- CH615442A5 CH615442A5 CH996575A CH996575A CH615442A5 CH 615442 A5 CH615442 A5 CH 615442A5 CH 996575 A CH996575 A CH 996575A CH 996575 A CH996575 A CH 996575A CH 615442 A5 CH615442 A5 CH 615442A5
- Authority
- CH
- Switzerland
- Prior art keywords
- formula
- group
- compound
- acid
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB33786/74A GB1516095A (en) | 1974-07-31 | 1974-07-31 | 17,21-diesters of 17alpha,21-dihydroxy-steroids of the pregnane series |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH615442A5 true CH615442A5 (en) | 1980-01-31 |
Family
ID=10357423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH996575A CH615442A5 (en) | 1974-07-31 | 1975-07-30 | Process for the preparation of 17alpha,21-diesters of 17alpha,21-dihydroxysteroids of the pregnane series |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS51125059A (nl) |
| BE (1) | BE831931A (nl) |
| CA (1) | CA1058610A (nl) |
| CH (1) | CH615442A5 (nl) |
| DE (1) | DE2534051A1 (nl) |
| DK (1) | DK139303B (nl) |
| ES (1) | ES439852A1 (nl) |
| FR (1) | FR2280383A1 (nl) |
| GB (1) | GB1516095A (nl) |
| IE (1) | IE42124B1 (nl) |
| NL (1) | NL7509075A (nl) |
| SE (1) | SE7508654L (nl) |
| ZA (1) | ZA754907B (nl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456602A (en) * | 1982-08-23 | 1984-06-26 | The Upjohn Company | Amine containing ester prodrugs of corticosteroids |
| US4443440A (en) * | 1982-08-30 | 1984-04-17 | The Upjohn Company | Amine containing ester prodrugs of corticosteroids |
| FR2600653B1 (fr) * | 1986-06-24 | 1988-12-16 | Pasteur Strasbourg Universite | Composes de synthese associative d'acides amines soufres ou non soufres avec des derives du d-4 pregnene 3,20-dione ou avec des derives du d-1,4 pregnadiene 3,20-dione aux proprietes glucocorticoides et anti-inflammatoires, procedes d'obtention, compositions pharmaceutiques les contenant. proprietes pharmacologiques et applications |
| DE4333920A1 (de) | 1993-10-05 | 1995-04-13 | Hoechst Ag | Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1044212B (it) * | 1971-03-17 | 1980-03-20 | Sigma Tau Ind Farmaceuti | Esteri del besametazone e betametazone |
| GB1440063A (en) * | 1972-08-11 | 1976-06-23 | Glaxo Lab Ltd | 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids |
-
1974
- 1974-07-31 GB GB33786/74A patent/GB1516095A/en not_active Expired
-
1975
- 1975-07-30 JP JP50092137A patent/JPS51125059A/ja active Pending
- 1975-07-30 SE SE7508654A patent/SE7508654L/xx unknown
- 1975-07-30 NL NL7509075A patent/NL7509075A/nl not_active Application Discontinuation
- 1975-07-30 CH CH996575A patent/CH615442A5/de not_active IP Right Cessation
- 1975-07-30 CA CA232,579A patent/CA1058610A/en not_active Expired
- 1975-07-30 ES ES439852A patent/ES439852A1/es not_active Expired
- 1975-07-30 ZA ZA00754907A patent/ZA754907B/xx unknown
- 1975-07-30 FR FR7523787A patent/FR2280383A1/fr active Granted
- 1975-07-30 BE BE158780A patent/BE831931A/xx unknown
- 1975-07-30 IE IE1708/75A patent/IE42124B1/en unknown
- 1975-07-30 DK DK346975AA patent/DK139303B/da unknown
- 1975-07-30 DE DE19752534051 patent/DE2534051A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2280383A1 (fr) | 1976-02-27 |
| SE7508654L (sv) | 1976-02-02 |
| NL7509075A (nl) | 1976-02-03 |
| CA1058610A (en) | 1979-07-17 |
| DK346975A (nl) | 1976-02-01 |
| DE2534051A1 (de) | 1976-02-19 |
| DK139303B (da) | 1979-01-29 |
| JPS51125059A (en) | 1976-11-01 |
| ZA754907B (en) | 1976-07-28 |
| IE42124B1 (en) | 1980-06-04 |
| GB1516095A (en) | 1978-06-28 |
| ES439852A1 (es) | 1977-03-01 |
| AU8353175A (en) | 1977-02-03 |
| DK139303C (nl) | 1979-08-06 |
| FR2280383B1 (nl) | 1978-10-06 |
| BE831931A (fr) | 1976-01-30 |
| IE42124L (en) | 1976-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |