CH609041A5 - Process for the preparation of novel benzylamines - Google Patents

Process for the preparation of novel benzylamines

Info

Publication number
CH609041A5
CH609041A5 CH528677A CH528677A CH609041A5 CH 609041 A5 CH609041 A5 CH 609041A5 CH 528677 A CH528677 A CH 528677A CH 528677 A CH528677 A CH 528677A CH 609041 A5 CH609041 A5 CH 609041A5
Authority
CH
Switzerland
Prior art keywords
benzylamines
novel
preparation
novel benzylamines
Prior art date
Application number
CH528677A
Other languages
English (en)
Inventor
Johannes Dr Keck
Klaus-Reinhold Dr Noll
Helmut Dr Pieper
Gerd Dr Krueger
Sigfrid Dr Pueschmann
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732318636 external-priority patent/DE2318636B2/de
Priority claimed from DE19742402989 external-priority patent/DE2402989C3/de
Priority claimed from DE19742405322 external-priority patent/DE2405322A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CH609041A5 publication Critical patent/CH609041A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/24—Camphidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH528677A 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines CH609041A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19732318636 DE2318636B2 (de) 1973-04-13 1973-04-13 Neue benzylamine, sie enthaltende arzneimittel und verfahren zu ihrer herstellung
DE19742402989 DE2402989C3 (de) 1974-01-23 1974-01-23 Neue Benzylamine, sie enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE19742405322 DE2405322A1 (de) 1974-02-05 1974-02-05 Neue verfahren zur herstellung von benzylaminen

Publications (1)

Publication Number Publication Date
CH609041A5 true CH609041A5 (en) 1979-02-15

Family

ID=27185183

Family Applications (2)

Application Number Title Priority Date Filing Date
CH493174A CH609327A5 (en) 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines
CH528677A CH609041A5 (en) 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH493174A CH609327A5 (en) 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines

Country Status (19)

Country Link
JP (1) JPS5634582B2 (de)
AT (1) AT332375B (de)
BG (1) BG25787A3 (de)
CA (1) CA1011748A (de)
CH (2) CH609327A5 (de)
CS (1) CS188920B2 (de)
DD (1) DD113748A5 (de)
ES (1) ES424432A1 (de)
FR (1) FR2225165B1 (de)
GB (1) GB1469187A (de)
HU (1) HU167971B (de)
IE (1) IE40146B1 (de)
IL (1) IL44623A (de)
NL (1) NL7404965A (de)
NO (1) NO138250C (de)
PL (2) PL89811B1 (de)
RO (3) RO69152A (de)
SE (1) SE411749B (de)
SU (2) SU517250A3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167562B (de) * 1974-01-19 1975-11-28
DE2926472A1 (de) * 1979-06-30 1981-01-15 Thomae Gmbh Dr K Neue benzoylderivate, deren herstellung und deren verwendung als arzneimittel
DE3100575A1 (de) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel"
US4735959A (en) * 1981-01-10 1988-04-05 Dr. Karl Thomae Gmbh Carboxylic acid amides and pharmaceutical compositions containing them
JPS60146849A (ja) * 1984-01-09 1985-08-02 Mitsui Toatsu Chem Inc アミノベンジルアミンの製造方法
JPH0365264A (ja) * 1989-08-03 1991-03-20 Sanko Denki Seisakusho:Kk 霧化装置
DE19529431C1 (de) * 1995-08-10 1996-12-12 Boehringer Ingelheim Kg Verfahren zur Herstellung von Benzylaminderivaten
CN112279774B (zh) * 2019-07-24 2023-05-30 成都施贝康生物医药科技有限公司 二溴苄基衍生物、其立体异构体或其盐及制法和应用

Also Published As

Publication number Publication date
DD113748A5 (de) 1975-06-20
IE40146B1 (en) 1979-03-28
RO69152A (ro) 1981-01-30
JPS5012030A (de) 1975-02-07
BG25787A3 (en) 1978-12-12
SU517250A3 (ru) 1976-06-05
SE411749B (sv) 1980-02-04
NO138250B (no) 1978-04-24
SU521836A3 (ru) 1976-07-15
ATA202374A (de) 1976-01-15
RO69291A (ro) 1983-04-29
GB1469187A (en) 1977-03-30
FR2225165B1 (de) 1977-09-09
NO741350L (no) 1974-10-15
CA1011748A (en) 1977-06-07
JPS5634582B2 (de) 1981-08-11
FR2225165A1 (de) 1974-11-08
RO69291B (ro) 1983-04-30
IL44623A0 (en) 1974-06-30
HU167971B (en) 1976-01-28
NL7404965A (de) 1974-10-15
RO70260A (ro) 1980-03-15
IE40146L (en) 1974-10-13
CH609327A5 (en) 1979-02-28
CS188920B2 (en) 1979-03-30
ES424432A1 (es) 1976-06-01
AT332375B (de) 1976-09-27
NO138250C (no) 1978-08-02
PL102867B1 (pl) 1979-04-30
IL44623A (en) 1978-01-31
PL89811B1 (de) 1976-12-31

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Legal Events

Date Code Title Description
PL Patent ceased