CH588491A5 - Prep. of oxoalkylxanthine - this has e.g. broncholytic and fibrinolytic activity - Google Patents

Prep. of oxoalkylxanthine - this has e.g. broncholytic and fibrinolytic activity

Info

Publication number
CH588491A5
CH588491A5 CH1019873A CH1019873A CH588491A5 CH 588491 A5 CH588491 A5 CH 588491A5 CH 1019873 A CH1019873 A CH 1019873A CH 1019873 A CH1019873 A CH 1019873A CH 588491 A5 CH588491 A5 CH 588491A5
Authority
CH
Switzerland
Prior art keywords
dimethylxanthine
hours
hydroxy
dependent
dehydrogenation
Prior art date
Application number
CH1019873A
Other languages
German (de)
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722234202 external-priority patent/DE2234202A1/de
Priority claimed from DE19732302772 external-priority patent/DE2302772C2/de
Priority claimed from DE19732330741 external-priority patent/DE2330741A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH588491A5 publication Critical patent/CH588491A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/20—Flavobacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/38—Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/69—Aspergillus oryzae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CH1019873A 1972-07-12 1973-07-12 Prep. of oxoalkylxanthine - this has e.g. broncholytic and fibrinolytic activity CH588491A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19722234202 DE2234202A1 (de) 1972-07-12 1972-07-12 Verfahren zur herstellung von oxoalkylxanthinen
DE19732302772 DE2302772C2 (de) 1973-01-20 1973-01-20 Mikrobiologisches Verfahren zur Herstellung von Oxoalkylxanthinen
DE19732330741 DE2330741A1 (de) 1973-06-16 1973-06-16 Verfahren zur herstellung von oxoalkylxanthinen

Publications (1)

Publication Number Publication Date
CH588491A5 true CH588491A5 (en) 1977-06-15

Family

ID=27184566

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1019873A CH588491A5 (en) 1972-07-12 1973-07-12 Prep. of oxoalkylxanthine - this has e.g. broncholytic and fibrinolytic activity

Country Status (5)

Country Link
JP (1) JPS5422517B2 (OSRAM)
CH (1) CH588491A5 (OSRAM)
ES (1) ES416696A1 (OSRAM)
NL (1) NL7309709A (OSRAM)
SE (1) SE400289B (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0157098A1 (en) * 1980-06-21 1985-10-09 Beecham Wuelfing GmbH & Co KG Xanthine derivatives, pharmaceuticals compositions containing them and a process for their preparation
AU1868195A (en) * 1994-01-28 1995-08-15 Cell Therapeutics, Inc. Cell signaling inhibitors

Also Published As

Publication number Publication date
ES416696A1 (es) 1976-02-16
SE400289B (sv) 1978-03-20
NL7309709A (OSRAM) 1974-01-15
JPS4951298A (OSRAM) 1974-05-18
JPS5422517B2 (OSRAM) 1979-08-07

Similar Documents

Publication Publication Date Title
DE2021465C3 (de) Verfahren zur Herstellung eines Enzympräparates, welches die OH-Gruppe in der ibeta-Stellung des Cholesterin« dehydriert
DE2849696A1 (de) Verfahren zur herstellung des antibiotikums c-15003 p-3
DE2302772C2 (de) Mikrobiologisches Verfahren zur Herstellung von Oxoalkylxanthinen
DE1299797B (de) Verfahren zur Herstellung des Antibioticums Rhi-12-648
DE1155413B (de) Verfahren zur biotechnischen Herstellung von Gibberellinsaeure
DE1958587B2 (de) Verfahren zur biochemischen abtrennung von l-menthol
DE1643149A1 (de) Verfahren zur Oxydation von Adamantanverbindungen
EP0661382B1 (de) Mikrobielles Verfahren zur Herstellung von Dihydroxyaceton
DE1929114C3 (de) Verfahren zur Herstellung von Rifamycin-L
DE1229522B (de) Verfahren zur Herstellung von Cycloalkanolen und/oder Cycloalkanonen sowie von Estern der Cycloalkanole
EP0014991A1 (de) Mikrobiologisches Verfahren zur Herstellung 7-alpha-hydroxylierter Steroide
DE960816C (de) Verfahren zur Herstellung oxydierter Steroide
EP0272605A2 (de) Verfahren zur Herstellung von optisch aktiven 2-Hydroxybuttersäurederivaten
EP0632836B1 (de) Verfahren zur herstellung von 17alpha-hydroxy-3-methoxy-8,14-seco-1,3,5(10), 9(11)estratetraen-14-on
EP0027829A1 (de) Verfahren zur Herstellung von 9-Alpha-hydroxy-4-androsten-3,17-dion
AT228930B (de) Verfahren zur Herstellung von N-substituierten 6-[Ureido-N']-penicillansäuren
DE1171413B (de) Verfahren zur Herstellung von 5-Keto-fruktose durch Gaerung
DE1695364C (de) Verfahren zur Herstellung von 2 Nitroimidazolen
DD140459A5 (de) Verfahren zur herstellung von 2,5-diketogluconsaeure
EP0496854B1 (de) Verfahren zur Herstellung von 20-METHYL-5,7-PREGNADIEN-3$g(b),21-DIOL-DERIVATIVEN
DE2129650C2 (de) Verfahren zur Herstellung von (-)-5(S)-Hydroxy-9-oxodecansäurelacton
DE1298975B (de) Verfahren zur Herstellung optisch-aktiver ª†- oder delta-Lactone
DE1792038B2 (de) Verfahren zur Herstellung einer Mischung von etwa gleichen Teilen Ergotamin und Ergocryptin
AT265531B (de) Verfahren zur Herstellung neuer heterocyclischer Verbindungen
EP0019162B1 (de) 12-alpha-Hydroxysteroide und deren Herstellung

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased