CH563364A5 - - Google Patents

Info

Publication number
CH563364A5
CH563364A5 CH1882972A CH1882972A CH563364A5 CH 563364 A5 CH563364 A5 CH 563364A5 CH 1882972 A CH1882972 A CH 1882972A CH 1882972 A CH1882972 A CH 1882972A CH 563364 A5 CH563364 A5 CH 563364A5
Authority
CH
Switzerland
Prior art keywords
sep
dimethyl
chlorophenyl
pyrroleacetic
acid
Prior art date
Application number
CH1882972A
Other languages
English (en)
French (fr)
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE777207A external-priority patent/BE777207A/xx
Priority claimed from BE785274A external-priority patent/BE785274R/xx
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of CH563364A5 publication Critical patent/CH563364A5/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CH1882972A 1971-12-23 1972-12-22 CH563364A5 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE777207A BE777207A (en) 1971-12-23 1971-12-23 3-pyrroleacetic acids - analgesics, antipyretics antiinflammatories prepd by hydrolysis of the corresp acid deriv
BE785274A BE785274R (en) 1972-06-22 1972-06-22 Pyrrole-3-acetic acids - useful as antiinflammatory analgesic and anti pyretic agents

Publications (1)

Publication Number Publication Date
CH563364A5 true CH563364A5 (ja) 1975-06-30

Family

ID=25656964

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1882972A CH563364A5 (ja) 1971-12-23 1972-12-22

Country Status (19)

Country Link
JP (1) JPS5318507B2 (ja)
AR (1) AR208494A1 (ja)
AT (1) AT323727B (ja)
AU (1) AU467602B2 (ja)
CA (1) CA991193A (ja)
CH (1) CH563364A5 (ja)
DD (1) DD104976A5 (ja)
DE (1) DE2261965A1 (ja)
DK (1) DK134599B (ja)
ES (1) ES409944A1 (ja)
FR (1) FR2164857B1 (ja)
GB (1) GB1406330A (ja)
HU (1) HU165900B (ja)
IE (1) IE37237B1 (ja)
IL (1) IL41146A (ja)
NL (1) NL7217521A (ja)
OA (1) OA04523A (ja)
PL (1) PL89071B1 (ja)
SE (1) SE388853B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2645234A1 (de) * 1976-10-07 1978-04-20 Basf Ag 2,5-dialkoxy-3-amino-methyltetrahydrofurane und verfahren zu ihrer herstellung
US4248784A (en) * 1977-02-25 1981-02-03 Sterling Drug Inc. Pyrrole-3-acetamides
DE3026402A1 (de) * 1980-07-11 1982-02-04 Syntex Corp., Palo Alto, Calif. Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen
US4851427A (en) * 1985-10-25 1989-07-25 Sandoz Pharm. Corp. Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use
EP0221025A1 (en) * 1985-10-25 1987-05-06 Sandoz Ag Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals
US4973704A (en) * 1985-10-25 1990-11-27 Sandoz Pharm. Corp. Pyrrolyl intermediates in the synthesis of pyrrole analogs of mevalonolactone and derivatives thereof
DE3915450A1 (de) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
US5935990A (en) * 1996-12-10 1999-08-10 G.D. Searle & Co. Substituted pyrrolyl compounds for the treatment of inflammation
JP5072965B2 (ja) 2006-08-03 2012-11-14 ロッタファルム・ソシエタ・ペル・アチオニ 高選択性および経口有効性cox−2インヒビターである3−置換−1,5−ジアリール−2−アルキルピロール

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1228301A (ja) * 1968-04-16 1971-04-15

Also Published As

Publication number Publication date
GB1406330A (en) 1975-09-17
IE37237L (en) 1973-06-23
DK134599B (da) 1976-12-06
AU5033872A (en) 1974-06-20
JPS4868562A (ja) 1973-09-18
HU165900B (ja) 1974-12-28
NL7217521A (ja) 1973-06-26
OA04523A (fr) 1980-03-30
DD104976A5 (ja) 1974-04-05
AR208494A1 (es) 1977-02-15
FR2164857B1 (ja) 1976-03-05
AU467602B2 (en) 1974-06-20
DE2261965A1 (de) 1973-06-28
FR2164857A1 (ja) 1973-08-03
IL41146A (en) 1977-03-31
JPS5318507B2 (ja) 1978-06-15
CA991193A (en) 1976-06-15
AT323727B (de) 1975-07-25
ES409944A1 (es) 1976-03-16
SE388853B (sv) 1976-10-18
PL89071B1 (en) 1976-10-30
DK134599C (ja) 1977-05-09
IE37237B1 (en) 1977-06-08

Similar Documents

Publication Publication Date Title
JP3775796B2 (ja) 抗炎症活性及び/又は鎮痛活性を有する硝酸エステル類及びそれらの製造方法
FR2658511A1 (fr) Nouveaux derives de benzimidazole et d'azabenzimidazole, antagonistes des recepteurs au thromboxane; leurs procedes de preparation, compositions pharmaceutiques les contenant.
CH616148A5 (ja)
IE47333B1 (en) New phenylacetic acid derivatives
CH563364A5 (ja)
EP0357403B1 (en) Substituted beta-diketones
US5185370A (en) Substituted β-diketones and their use
FR2584713A1 (fr) Nouveaux derives de l'indole carboxamide, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
EP0005559B1 (de) Phenylaminothiophenessigsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
CH630606A5 (en) Phenylamidine derivatives useful especially in therapeutics
LU83307A1 (fr) Derives d'adenosine a activite anti-inflammatoire et analgesique,ainsi que des compositions therapeutiques contenant ces derives comme principe actif
EP0017543B1 (fr) Dérivés du benzothiazole, leur procédé de préparation et leurs applications en thérapeutique
EP0001947B1 (fr) Dérivés de l'amino-2 thiazoline, procédé de préparation et compositions pharmaceutiques les contenant
FR2491456A1 (ja)
EP0061406B1 (fr) Dérivés d'acide benzamido-alkyl-hydroxamique, procédé de préparation et composition thérapeutique
LU86706A1 (fr) Nouveaux derives du benzo(4,5)cyclohepta(1,2-b)thiophene,leur preparation et leur utilisation comme medicaments
CA1106376A (fr) Procede de preparation de nouveaux esters anthraniliques
FR2491471A1 (fr) Benzoxazolinones substituees, leur preparation et leur application en therapeutique
EP0039646A1 (fr) Nouvelles benzo (1,4) dioxines, leurs méthodes de préparation et leur application en thérapeutique
FR2478638A1 (fr) Ester d'acide p-(4-chlorobenzoyl)-phenoxyisobutyrique de la 3-hydroxy-quinuclidine et ses derives, procede pour leur preparation et medicaments les contenant, utiles notamment comme hypocholesterolemiants et hypotriglyceridemiants
FR2677016A1 (fr) Nouveaux derives d'amide antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.
FR2690442A1 (fr) Nouveaux dérivés de pyrazolopyrimidine antagonistes des récepteurs à l'Angiotensine II; leurs procédés de préparation, compositions pharmaceutiques les contenant .
CH518266A (fr) Procédé de préparation d'un nouveau dérivé de la xylidine
WO1998015528A1 (fr) Nouveaux derives diarylmethylenes, leurs procedes de preparation et leurs utilisations en therapeutique
FR2589156A1 (fr) Acides 4-(3-thienyl)-phenyl-alcanoiques, leur preparation et medicaments les contenant

Legal Events

Date Code Title Description
PL Patent ceased