SE388853B - Analogiforfarande att framstella derivat av 1-fenyl-2,5-dimetyl-3-pyrrol-ettiksyra med terapeutisk verkan - Google Patents

Analogiforfarande att framstella derivat av 1-fenyl-2,5-dimetyl-3-pyrrol-ettiksyra med terapeutisk verkan

Info

Publication number
SE388853B
SE388853B SE7216774A SE1677472A SE388853B SE 388853 B SE388853 B SE 388853B SE 7216774 A SE7216774 A SE 7216774A SE 1677472 A SE1677472 A SE 1677472A SE 388853 B SE388853 B SE 388853B
Authority
SE
Sweden
Prior art keywords
pyrrole
dimethyl
phenyl
therapeutic effect
preparing derivatives
Prior art date
Application number
SE7216774A
Other languages
English (en)
Inventor
G Lambelin
J Gillet C Roba
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE777207A external-priority patent/BE777207A/xx
Priority claimed from BE785274A external-priority patent/BE785274R/xx
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of SE388853B publication Critical patent/SE388853B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
SE7216774A 1971-12-23 1972-12-21 Analogiforfarande att framstella derivat av 1-fenyl-2,5-dimetyl-3-pyrrol-ettiksyra med terapeutisk verkan SE388853B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE777207A BE777207A (en) 1971-12-23 1971-12-23 3-pyrroleacetic acids - analgesics, antipyretics antiinflammatories prepd by hydrolysis of the corresp acid deriv
BE785274A BE785274R (en) 1972-06-22 1972-06-22 Pyrrole-3-acetic acids - useful as antiinflammatory analgesic and anti pyretic agents

Publications (1)

Publication Number Publication Date
SE388853B true SE388853B (sv) 1976-10-18

Family

ID=25656964

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7216774A SE388853B (sv) 1971-12-23 1972-12-21 Analogiforfarande att framstella derivat av 1-fenyl-2,5-dimetyl-3-pyrrol-ettiksyra med terapeutisk verkan

Country Status (19)

Country Link
JP (1) JPS5318507B2 (sv)
AR (1) AR208494A1 (sv)
AT (1) AT323727B (sv)
AU (1) AU467602B2 (sv)
CA (1) CA991193A (sv)
CH (1) CH563364A5 (sv)
DD (1) DD104976A5 (sv)
DE (1) DE2261965A1 (sv)
DK (1) DK134599B (sv)
ES (1) ES409944A1 (sv)
FR (1) FR2164857B1 (sv)
GB (1) GB1406330A (sv)
HU (1) HU165900B (sv)
IE (1) IE37237B1 (sv)
IL (1) IL41146A (sv)
NL (1) NL7217521A (sv)
OA (1) OA04523A (sv)
PL (1) PL89071B1 (sv)
SE (1) SE388853B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2645234A1 (de) * 1976-10-07 1978-04-20 Basf Ag 2,5-dialkoxy-3-amino-methyltetrahydrofurane und verfahren zu ihrer herstellung
US4248784A (en) * 1977-02-25 1981-02-03 Sterling Drug Inc. Pyrrole-3-acetamides
DE3026402A1 (de) * 1980-07-11 1982-02-04 Syntex Corp., Palo Alto, Calif. Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen
US4973704A (en) * 1985-10-25 1990-11-27 Sandoz Pharm. Corp. Pyrrolyl intermediates in the synthesis of pyrrole analogs of mevalonolactone and derivatives thereof
US4851427A (en) * 1985-10-25 1989-07-25 Sandoz Pharm. Corp. Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use
HUT48208A (en) * 1985-10-25 1989-05-29 Sandoz Ag Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (de) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
EP0946507B1 (en) * 1996-12-10 2003-09-24 G.D. SEARLE & CO. Substituted pyrrolyl compounds for the treatment of inflammation
ES2555511T3 (es) * 2006-08-03 2016-01-04 Rottapharm Biotech S.R.L. Inhibidores de COX-2 altamente selectivos y eficaces por vía oral de 1,5-diaril-2-alquil-pirroles 3-sustituidos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1228301A (sv) * 1968-04-16 1971-04-15

Also Published As

Publication number Publication date
GB1406330A (en) 1975-09-17
CH563364A5 (sv) 1975-06-30
HU165900B (sv) 1974-12-28
CA991193A (en) 1976-06-15
FR2164857B1 (sv) 1976-03-05
OA04523A (fr) 1980-03-30
DD104976A5 (sv) 1974-04-05
AT323727B (de) 1975-07-25
NL7217521A (sv) 1973-06-26
IE37237B1 (en) 1977-06-08
AU467602B2 (en) 1974-06-20
ES409944A1 (es) 1976-03-16
IE37237L (en) 1973-06-23
DE2261965A1 (de) 1973-06-28
JPS4868562A (sv) 1973-09-18
IL41146A (en) 1977-03-31
AR208494A1 (es) 1977-02-15
JPS5318507B2 (sv) 1978-06-15
PL89071B1 (en) 1976-10-30
DK134599B (da) 1976-12-06
AU5033872A (en) 1974-06-20
FR2164857A1 (sv) 1973-08-03
DK134599C (sv) 1977-05-09

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