IL41146A - Derivatives of pyrroleacetic acids salts thereof and process for their preparation - Google Patents

Derivatives of pyrroleacetic acids salts thereof and process for their preparation

Info

Publication number
IL41146A
IL41146A IL41146A IL4114672A IL41146A IL 41146 A IL41146 A IL 41146A IL 41146 A IL41146 A IL 41146A IL 4114672 A IL4114672 A IL 4114672A IL 41146 A IL41146 A IL 41146A
Authority
IL
Israel
Prior art keywords
acid
chlorophenyl
dimethyl
salt
derivative
Prior art date
Application number
IL41146A
Other languages
English (en)
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE777207A external-priority patent/BE777207A/xx
Priority claimed from BE785274A external-priority patent/BE785274R/xx
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of IL41146A publication Critical patent/IL41146A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IL41146A 1971-12-23 1972-12-22 Derivatives of pyrroleacetic acids salts thereof and process for their preparation IL41146A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE777207A BE777207A (en) 1971-12-23 1971-12-23 3-pyrroleacetic acids - analgesics, antipyretics antiinflammatories prepd by hydrolysis of the corresp acid deriv
BE785274A BE785274R (en) 1972-06-22 1972-06-22 Pyrrole-3-acetic acids - useful as antiinflammatory analgesic and anti pyretic agents

Publications (1)

Publication Number Publication Date
IL41146A true IL41146A (en) 1977-03-31

Family

ID=25656964

Family Applications (1)

Application Number Title Priority Date Filing Date
IL41146A IL41146A (en) 1971-12-23 1972-12-22 Derivatives of pyrroleacetic acids salts thereof and process for their preparation

Country Status (19)

Country Link
JP (1) JPS5318507B2 (sv)
AR (1) AR208494A1 (sv)
AT (1) AT323727B (sv)
AU (1) AU467602B2 (sv)
CA (1) CA991193A (sv)
CH (1) CH563364A5 (sv)
DD (1) DD104976A5 (sv)
DE (1) DE2261965A1 (sv)
DK (1) DK134599B (sv)
ES (1) ES409944A1 (sv)
FR (1) FR2164857B1 (sv)
GB (1) GB1406330A (sv)
HU (1) HU165900B (sv)
IE (1) IE37237B1 (sv)
IL (1) IL41146A (sv)
NL (1) NL7217521A (sv)
OA (1) OA04523A (sv)
PL (1) PL89071B1 (sv)
SE (1) SE388853B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2645234A1 (de) * 1976-10-07 1978-04-20 Basf Ag 2,5-dialkoxy-3-amino-methyltetrahydrofurane und verfahren zu ihrer herstellung
US4248784A (en) * 1977-02-25 1981-02-03 Sterling Drug Inc. Pyrrole-3-acetamides
DE3026402A1 (de) * 1980-07-11 1982-02-04 Syntex Corp., Palo Alto, Calif. Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen
US4973704A (en) * 1985-10-25 1990-11-27 Sandoz Pharm. Corp. Pyrrolyl intermediates in the synthesis of pyrrole analogs of mevalonolactone and derivatives thereof
WO1987002662A2 (en) * 1985-10-25 1987-05-07 Sandoz Ag Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals
US4851427A (en) * 1985-10-25 1989-07-25 Sandoz Pharm. Corp. Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (de) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
PT946507E (pt) * 1996-12-10 2004-02-27 Searle & Co Compostos de pirrolilo substituidos para o tratamento da inflamacao
JP5072965B2 (ja) * 2006-08-03 2012-11-14 ロッタファルム・ソシエタ・ペル・アチオニ 高選択性および経口有効性cox−2インヒビターである3−置換−1,5−ジアリール−2−アルキルピロール

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1228301A (sv) * 1968-04-16 1971-04-15

Also Published As

Publication number Publication date
DD104976A5 (sv) 1974-04-05
PL89071B1 (en) 1976-10-30
CA991193A (en) 1976-06-15
IE37237L (en) 1973-06-23
JPS4868562A (sv) 1973-09-18
FR2164857A1 (sv) 1973-08-03
GB1406330A (en) 1975-09-17
NL7217521A (sv) 1973-06-26
FR2164857B1 (sv) 1976-03-05
AU467602B2 (en) 1974-06-20
DE2261965A1 (de) 1973-06-28
IE37237B1 (en) 1977-06-08
DK134599C (sv) 1977-05-09
AR208494A1 (es) 1977-02-15
JPS5318507B2 (sv) 1978-06-15
AU5033872A (en) 1974-06-20
SE388853B (sv) 1976-10-18
DK134599B (da) 1976-12-06
CH563364A5 (sv) 1975-06-30
HU165900B (sv) 1974-12-28
OA04523A (fr) 1980-03-30
AT323727B (de) 1975-07-25
ES409944A1 (es) 1976-03-16

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