JPS5318507B2 - - Google Patents
Info
- Publication number
- JPS5318507B2 JPS5318507B2 JP404973A JP404973A JPS5318507B2 JP S5318507 B2 JPS5318507 B2 JP S5318507B2 JP 404973 A JP404973 A JP 404973A JP 404973 A JP404973 A JP 404973A JP S5318507 B2 JPS5318507 B2 JP S5318507B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE777207A BE777207A (en) | 1971-12-23 | 1971-12-23 | 3-pyrroleacetic acids - analgesics, antipyretics antiinflammatories prepd by hydrolysis of the corresp acid deriv |
| BE785274A BE785274R (en) | 1972-06-22 | 1972-06-22 | Pyrrole-3-acetic acids - useful as antiinflammatory analgesic and anti pyretic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS4868562A JPS4868562A (ja) | 1973-09-18 |
| JPS5318507B2 true JPS5318507B2 (ja) | 1978-06-15 |
Family
ID=25656964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP404973A Expired JPS5318507B2 (ja) | 1971-12-23 | 1972-12-23 |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5318507B2 (ja) |
| AR (1) | AR208494A1 (ja) |
| AT (1) | AT323727B (ja) |
| AU (1) | AU467602B2 (ja) |
| CA (1) | CA991193A (ja) |
| CH (1) | CH563364A5 (ja) |
| DD (1) | DD104976A5 (ja) |
| DE (1) | DE2261965A1 (ja) |
| DK (1) | DK134599B (ja) |
| ES (1) | ES409944A1 (ja) |
| FR (1) | FR2164857B1 (ja) |
| GB (1) | GB1406330A (ja) |
| HU (1) | HU165900B (ja) |
| IE (1) | IE37237B1 (ja) |
| IL (1) | IL41146A (ja) |
| NL (1) | NL7217521A (ja) |
| OA (1) | OA04523A (ja) |
| PL (1) | PL89071B1 (ja) |
| SE (1) | SE388853B (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2645234A1 (de) * | 1976-10-07 | 1978-04-20 | Basf Ag | 2,5-dialkoxy-3-amino-methyltetrahydrofurane und verfahren zu ihrer herstellung |
| US4248784A (en) * | 1977-02-25 | 1981-02-03 | Sterling Drug Inc. | Pyrrole-3-acetamides |
| DE3026402A1 (de) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
| US4851427A (en) * | 1985-10-25 | 1989-07-25 | Sandoz Pharm. Corp. | Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use |
| US4973704A (en) * | 1985-10-25 | 1990-11-27 | Sandoz Pharm. Corp. | Pyrrolyl intermediates in the synthesis of pyrrole analogs of mevalonolactone and derivatives thereof |
| WO1987002662A2 (en) * | 1985-10-25 | 1987-05-07 | Sandoz Ag | Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals |
| DE3915450A1 (de) * | 1989-05-11 | 1990-11-15 | Gerd Prof Dr Dannhardt | Substituierte pyrrolverbindungen und deren anwendung in der pharmazie |
| US5260451A (en) * | 1989-05-11 | 1993-11-09 | Merckle Gmbh | Substituted pyrrole compounds and use thereof in pharmaceutical compositions |
| ES2208964T3 (es) * | 1996-12-10 | 2004-06-16 | G.D. SEARLE & CO. | Compuestos de pirrolilo substituidos para el tratamiento de la inflamacion. |
| EP2059504B1 (en) * | 2006-08-03 | 2015-09-09 | Rottapharm Biotech S.r.l. | 3-substituted-1,5-diarly-2-alkyl-pyrroles highly selective and orally effective cox-2 inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1228301A (ja) * | 1968-04-16 | 1971-04-15 |
-
1972
- 1972-12-18 DE DE19722261965 patent/DE2261965A1/de active Pending
- 1972-12-20 HU HUCO272A patent/HU165900B/hu unknown
- 1972-12-20 GB GB5877272A patent/GB1406330A/en not_active Expired
- 1972-12-20 AU AU50338/72A patent/AU467602B2/en not_active Expired
- 1972-12-21 IE IE1781/72A patent/IE37237B1/xx unknown
- 1972-12-21 DK DK638372AA patent/DK134599B/da unknown
- 1972-12-21 AT AT1093772A patent/AT323727B/de not_active IP Right Cessation
- 1972-12-21 SE SE7216774A patent/SE388853B/xx unknown
- 1972-12-21 AR AR245771A patent/AR208494A1/es active
- 1972-12-21 PL PL1972159744A patent/PL89071B1/pl unknown
- 1972-12-22 NL NL7217521A patent/NL7217521A/xx unknown
- 1972-12-22 FR FR7245868A patent/FR2164857B1/fr not_active Expired
- 1972-12-22 ES ES409944A patent/ES409944A1/es not_active Expired
- 1972-12-22 CA CA159,778A patent/CA991193A/en not_active Expired
- 1972-12-22 CH CH1882972A patent/CH563364A5/fr not_active IP Right Cessation
- 1972-12-22 IL IL41146A patent/IL41146A/en unknown
- 1972-12-22 DD DD168267*A patent/DD104976A5/xx unknown
- 1972-12-23 OA OA54792A patent/OA04523A/xx unknown
- 1972-12-23 JP JP404973A patent/JPS5318507B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL41146A (en) | 1977-03-31 |
| IE37237B1 (en) | 1977-06-08 |
| SE388853B (sv) | 1976-10-18 |
| FR2164857B1 (ja) | 1976-03-05 |
| DD104976A5 (ja) | 1974-04-05 |
| DK134599B (da) | 1976-12-06 |
| AU5033872A (en) | 1974-06-20 |
| DE2261965A1 (de) | 1973-06-28 |
| AU467602B2 (en) | 1974-06-20 |
| CA991193A (en) | 1976-06-15 |
| JPS4868562A (ja) | 1973-09-18 |
| FR2164857A1 (ja) | 1973-08-03 |
| AR208494A1 (es) | 1977-02-15 |
| NL7217521A (ja) | 1973-06-26 |
| IE37237L (en) | 1973-06-23 |
| GB1406330A (en) | 1975-09-17 |
| OA04523A (fr) | 1980-03-30 |
| ES409944A1 (es) | 1976-03-16 |
| HU165900B (ja) | 1974-12-28 |
| AT323727B (de) | 1975-07-25 |
| PL89071B1 (en) | 1976-10-30 |
| CH563364A5 (ja) | 1975-06-30 |
| DK134599C (ja) | 1977-05-09 |