SE388853B - ANALOGICAL PROCEDURE FOR PREPARING DERIVATIVES OF 1-PHENYL-2,5-DIMETHYL-3-PYRROLE-ACTIC ACID WITH THERAPEUTIC EFFECT - Google Patents
ANALOGICAL PROCEDURE FOR PREPARING DERIVATIVES OF 1-PHENYL-2,5-DIMETHYL-3-PYRROLE-ACTIC ACID WITH THERAPEUTIC EFFECTInfo
- Publication number
- SE388853B SE388853B SE7216774A SE1677472A SE388853B SE 388853 B SE388853 B SE 388853B SE 7216774 A SE7216774 A SE 7216774A SE 1677472 A SE1677472 A SE 1677472A SE 388853 B SE388853 B SE 388853B
- Authority
- SE
- Sweden
- Prior art keywords
- pyrrole
- dimethyl
- phenyl
- therapeutic effect
- preparing derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE777207A BE777207A (en) | 1971-12-23 | 1971-12-23 | 3-pyrroleacetic acids - analgesics, antipyretics antiinflammatories prepd by hydrolysis of the corresp acid deriv |
BE785274A BE785274R (en) | 1972-06-22 | 1972-06-22 | Pyrrole-3-acetic acids - useful as antiinflammatory analgesic and anti pyretic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
SE388853B true SE388853B (en) | 1976-10-18 |
Family
ID=25656964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7216774A SE388853B (en) | 1971-12-23 | 1972-12-21 | ANALOGICAL PROCEDURE FOR PREPARING DERIVATIVES OF 1-PHENYL-2,5-DIMETHYL-3-PYRROLE-ACTIC ACID WITH THERAPEUTIC EFFECT |
Country Status (19)
Country | Link |
---|---|
JP (1) | JPS5318507B2 (en) |
AR (1) | AR208494A1 (en) |
AT (1) | AT323727B (en) |
AU (1) | AU467602B2 (en) |
CA (1) | CA991193A (en) |
CH (1) | CH563364A5 (en) |
DD (1) | DD104976A5 (en) |
DE (1) | DE2261965A1 (en) |
DK (1) | DK134599B (en) |
ES (1) | ES409944A1 (en) |
FR (1) | FR2164857B1 (en) |
GB (1) | GB1406330A (en) |
HU (1) | HU165900B (en) |
IE (1) | IE37237B1 (en) |
IL (1) | IL41146A (en) |
NL (1) | NL7217521A (en) |
OA (1) | OA04523A (en) |
PL (1) | PL89071B1 (en) |
SE (1) | SE388853B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2645234A1 (en) * | 1976-10-07 | 1978-04-20 | Basf Ag | 2,5-DIALKOXY-3-AMINO-METHYLTETRAHYDROFURANS AND THE METHOD FOR THEIR PRODUCTION |
US4248784A (en) * | 1977-02-25 | 1981-02-03 | Sterling Drug Inc. | Pyrrole-3-acetamides |
DE3026402A1 (en) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Non-steroidal antiinflammatory agents - for treatment of micro:vascular disease, e.g. diabetic retinopathy or diabetic nephropathy |
US4973704A (en) * | 1985-10-25 | 1990-11-27 | Sandoz Pharm. Corp. | Pyrrolyl intermediates in the synthesis of pyrrole analogs of mevalonolactone and derivatives thereof |
US4851427A (en) * | 1985-10-25 | 1989-07-25 | Sandoz Pharm. Corp. | Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use |
HUT48208A (en) * | 1985-10-25 | 1989-05-29 | Sandoz Ag | Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds |
US5260451A (en) * | 1989-05-11 | 1993-11-09 | Merckle Gmbh | Substituted pyrrole compounds and use thereof in pharmaceutical compositions |
DE3915450A1 (en) * | 1989-05-11 | 1990-11-15 | Gerd Prof Dr Dannhardt | SUBSTITUTED PYRROL COMPOUNDS AND THEIR USE IN PHARMACY |
DK0946507T3 (en) * | 1996-12-10 | 2004-01-26 | Searle & Co | Substituted pyrrolyl compounds for the treatment of inflammation |
JP5072965B2 (en) | 2006-08-03 | 2012-11-14 | ロッタファルム・ソシエタ・ペル・アチオニ | 3-Substituted-1,5-diaryl-2-alkylpyrroles which are highly selective and orally effective COX-2 inhibitors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1228301A (en) * | 1968-04-16 | 1971-04-15 |
-
1972
- 1972-12-18 DE DE19722261965 patent/DE2261965A1/en active Pending
- 1972-12-20 HU HUCO272A patent/HU165900B/hu unknown
- 1972-12-20 AU AU50338/72A patent/AU467602B2/en not_active Expired
- 1972-12-20 GB GB5877272A patent/GB1406330A/en not_active Expired
- 1972-12-21 DK DK638372AA patent/DK134599B/en unknown
- 1972-12-21 SE SE7216774A patent/SE388853B/en unknown
- 1972-12-21 IE IE1781/72A patent/IE37237B1/en unknown
- 1972-12-21 AT AT1093772A patent/AT323727B/en not_active IP Right Cessation
- 1972-12-21 AR AR245771A patent/AR208494A1/en active
- 1972-12-21 PL PL1972159744A patent/PL89071B1/en unknown
- 1972-12-22 CA CA159,778A patent/CA991193A/en not_active Expired
- 1972-12-22 DD DD168267*A patent/DD104976A5/xx unknown
- 1972-12-22 NL NL7217521A patent/NL7217521A/xx unknown
- 1972-12-22 ES ES409944A patent/ES409944A1/en not_active Expired
- 1972-12-22 IL IL41146A patent/IL41146A/en unknown
- 1972-12-22 CH CH1882972A patent/CH563364A5/fr not_active IP Right Cessation
- 1972-12-22 FR FR7245868A patent/FR2164857B1/fr not_active Expired
- 1972-12-23 OA OA54792A patent/OA04523A/en unknown
- 1972-12-23 JP JP404973A patent/JPS5318507B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2164857B1 (en) | 1976-03-05 |
NL7217521A (en) | 1973-06-26 |
JPS4868562A (en) | 1973-09-18 |
GB1406330A (en) | 1975-09-17 |
HU165900B (en) | 1974-12-28 |
AR208494A1 (en) | 1977-02-15 |
AU467602B2 (en) | 1974-06-20 |
IE37237L (en) | 1973-06-23 |
OA04523A (en) | 1980-03-30 |
JPS5318507B2 (en) | 1978-06-15 |
ES409944A1 (en) | 1976-03-16 |
DK134599B (en) | 1976-12-06 |
DK134599C (en) | 1977-05-09 |
DE2261965A1 (en) | 1973-06-28 |
FR2164857A1 (en) | 1973-08-03 |
IL41146A (en) | 1977-03-31 |
PL89071B1 (en) | 1976-10-30 |
DD104976A5 (en) | 1974-04-05 |
CH563364A5 (en) | 1975-06-30 |
AT323727B (en) | 1975-07-25 |
AU5033872A (en) | 1974-06-20 |
CA991193A (en) | 1976-06-15 |
IE37237B1 (en) | 1977-06-08 |
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