DK134599B - Analogous process for the preparation of pyrroleacetic acid derivatives and their salts. - Google Patents

Analogous process for the preparation of pyrroleacetic acid derivatives and their salts.

Info

Publication number
DK134599B
DK134599B DK638372AA DK638372A DK134599B DK 134599 B DK134599 B DK 134599B DK 638372A A DK638372A A DK 638372AA DK 638372 A DK638372 A DK 638372A DK 134599 B DK134599 B DK 134599B
Authority
DK
Denmark
Prior art keywords
salts
preparation
acid derivatives
analogous process
pyrroleacetic acid
Prior art date
Application number
DK638372AA
Other languages
Danish (da)
Other versions
DK134599C (en
Inventor
Georges Lambelin
Joseph Roba
Claude Gillet
Nguyen Phuc Buu-Hoi
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE777207A external-priority patent/BE777207A/en
Priority claimed from BE785274A external-priority patent/BE785274R/en
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of DK134599B publication Critical patent/DK134599B/en
Application granted granted Critical
Publication of DK134599C publication Critical patent/DK134599C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
DK638372AA 1971-12-23 1972-12-21 Analogous process for the preparation of pyrroleacetic acid derivatives and their salts. DK134599B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE777207A BE777207A (en) 1971-12-23 1971-12-23 3-pyrroleacetic acids - analgesics, antipyretics antiinflammatories prepd by hydrolysis of the corresp acid deriv
BE785274A BE785274R (en) 1972-06-22 1972-06-22 Pyrrole-3-acetic acids - useful as antiinflammatory analgesic and anti pyretic agents

Publications (2)

Publication Number Publication Date
DK134599B true DK134599B (en) 1976-12-06
DK134599C DK134599C (en) 1977-05-09

Family

ID=25656964

Family Applications (1)

Application Number Title Priority Date Filing Date
DK638372AA DK134599B (en) 1971-12-23 1972-12-21 Analogous process for the preparation of pyrroleacetic acid derivatives and their salts.

Country Status (19)

Country Link
JP (1) JPS5318507B2 (en)
AR (1) AR208494A1 (en)
AT (1) AT323727B (en)
AU (1) AU467602B2 (en)
CA (1) CA991193A (en)
CH (1) CH563364A5 (en)
DD (1) DD104976A5 (en)
DE (1) DE2261965A1 (en)
DK (1) DK134599B (en)
ES (1) ES409944A1 (en)
FR (1) FR2164857B1 (en)
GB (1) GB1406330A (en)
HU (1) HU165900B (en)
IE (1) IE37237B1 (en)
IL (1) IL41146A (en)
NL (1) NL7217521A (en)
OA (1) OA04523A (en)
PL (1) PL89071B1 (en)
SE (1) SE388853B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2645234A1 (en) * 1976-10-07 1978-04-20 Basf Ag 2,5-DIALKOXY-3-AMINO-METHYLTETRAHYDROFURANS AND THE METHOD FOR THEIR PRODUCTION
US4248784A (en) * 1977-02-25 1981-02-03 Sterling Drug Inc. Pyrrole-3-acetamides
DE3026402A1 (en) * 1980-07-11 1982-02-04 Syntex Corp., Palo Alto, Calif. Non-steroidal antiinflammatory agents - for treatment of micro:vascular disease, e.g. diabetic retinopathy or diabetic nephropathy
US4973704A (en) * 1985-10-25 1990-11-27 Sandoz Pharm. Corp. Pyrrolyl intermediates in the synthesis of pyrrole analogs of mevalonolactone and derivatives thereof
US4851427A (en) * 1985-10-25 1989-07-25 Sandoz Pharm. Corp. Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use
KR900001212B1 (en) * 1985-10-25 1990-02-28 산도즈 파마슈티칼스 코오포레이숀 Mevalonolactones and their derivatives and process and pharmaceutical use, thereof
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (en) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt SUBSTITUTED PYRROL COMPOUNDS AND THEIR USE IN PHARMACY
CA2273836A1 (en) * 1996-12-10 1998-06-18 G.D. Searle & Co. Substituted pyrrolyl compounds for the treatment of inflammation
JP5072965B2 (en) * 2006-08-03 2012-11-14 ロッタファルム・ソシエタ・ペル・アチオニ 3-Substituted-1,5-diaryl-2-alkylpyrroles which are highly selective and orally effective COX-2 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1228301A (en) * 1968-04-16 1971-04-15

Also Published As

Publication number Publication date
AU467602B2 (en) 1974-06-20
NL7217521A (en) 1973-06-26
ES409944A1 (en) 1976-03-16
PL89071B1 (en) 1976-10-30
CH563364A5 (en) 1975-06-30
DD104976A5 (en) 1974-04-05
GB1406330A (en) 1975-09-17
FR2164857A1 (en) 1973-08-03
IE37237B1 (en) 1977-06-08
JPS4868562A (en) 1973-09-18
AT323727B (en) 1975-07-25
CA991193A (en) 1976-06-15
IL41146A (en) 1977-03-31
SE388853B (en) 1976-10-18
AR208494A1 (en) 1977-02-15
AU5033872A (en) 1974-06-20
IE37237L (en) 1973-06-23
HU165900B (en) 1974-12-28
OA04523A (en) 1980-03-30
JPS5318507B2 (en) 1978-06-15
DK134599C (en) 1977-05-09
FR2164857B1 (en) 1976-03-05
DE2261965A1 (en) 1973-06-28

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