CH523320A - Verfahren zur Herstellung einer zellfreien Penicillinacylase - Google Patents

Verfahren zur Herstellung einer zellfreien Penicillinacylase

Info

Publication number
CH523320A
CH523320A CH226769A CH226769A CH523320A CH 523320 A CH523320 A CH 523320A CH 226769 A CH226769 A CH 226769A CH 226769 A CH226769 A CH 226769A CH 523320 A CH523320 A CH 523320A
Authority
CH
Switzerland
Prior art keywords
cell
production
penicillin acylase
free penicillin
free
Prior art date
Application number
CH226769A
Other languages
English (en)
Inventor
Per Staffan Delin
Bertil Aake Ekstroem
Berndt Olof Harald Sjoeberg
Karl Hugo Thelin
Lars Soelve Nathorst-Westfelt
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB57373/68A external-priority patent/GB1261711A/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of CH523320A publication Critical patent/CH523320A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position
CH226769A 1968-02-15 1969-02-14 Verfahren zur Herstellung einer zellfreien Penicillinacylase CH523320A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB754468 1968-02-15
GB57373/68A GB1261711A (en) 1968-02-15 1968-12-03 Process for producing a penicillin acylose composition

Publications (1)

Publication Number Publication Date
CH523320A true CH523320A (de) 1972-05-31

Family

ID=26241501

Family Applications (2)

Application Number Title Priority Date Filing Date
CH226769A CH523320A (de) 1968-02-15 1969-02-14 Verfahren zur Herstellung einer zellfreien Penicillinacylase
CH79172A CH538540A (de) 1968-02-15 1972-02-14 Verfahren zur Herstellung eines Enzympräparates

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH79172A CH538540A (de) 1968-02-15 1972-02-14 Verfahren zur Herstellung eines Enzympräparates

Country Status (17)

Country Link
JP (2) JPS4833386B1 (de)
AT (2) AT297218B (de)
BE (1) BE727506A (de)
CA (1) CA941769A (de)
CH (2) CH523320A (de)
CS (1) CS155970B2 (de)
DE (4) DE1907365A1 (de)
DK (1) DK128421B (de)
ES (4) ES363592A1 (de)
FI (1) FI47109C (de)
FR (2) FR2001977A1 (de)
IE (1) IE32962B1 (de)
IT (1) IT1061759B (de)
NL (1) NL158547B (de)
NO (3) NO131388C (de)
SE (3) SE352643B (de)
SU (1) SU404195A3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1357317A (en) * 1970-08-27 1974-06-19 Beecham Group Ltd Enzymes
IL39158A (en) * 1971-04-28 1977-08-31 Snam Progetti Enzymatic scission and synthesis of penicillins and cephalosporins
BE791748A (fr) * 1971-11-23 1973-05-22 Bayer Ag Procede de production d'acide 6-aminopenicillanique par ruptureenzymatique de penicillines
JPS5420193A (en) * 1977-07-12 1979-02-15 Tanabe Seiyaku Co Ltd Immobilized aminoacylase and its preparation
GB9718740D0 (en) 1997-09-05 1997-11-12 Advanced Phytonics Ltd Improvements in or relating to the preparation of a compound
DE10123048A1 (de) * 2001-05-11 2002-11-21 Bermatingen Maschf Messer für Kreiselmulchgeräte

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB877898A (en) * 1956-12-06 1961-09-20 Apv Co Ltd A new or improved method of liberating enzymes
GB1118566A (en) * 1964-11-25 1968-07-03 Beecham Group Ltd Production of 6-aminopenicillanic acid

Also Published As

Publication number Publication date
ES363592A1 (es) 1970-12-16
ES384026A1 (es) 1973-04-16
NL158547B (nl) 1978-11-15
FR2081316B1 (de) 1974-08-30
DK128421B (da) 1974-04-29
IE32962L (en) 1969-08-15
DE1907365A1 (de) 1969-09-11
ES384025A1 (es) 1973-04-16
FR2081316A1 (de) 1971-12-03
DE1966427B2 (de) 1979-07-12
FI47109C (fi) 1973-09-10
SE400291B (sv) 1978-03-20
ES384027A1 (es) 1973-06-01
DE1933301A1 (de) 1970-06-25
DE1966428A1 (de) 1972-09-14
DE1966427A1 (de) 1972-08-24
NO131388B (de) 1975-02-10
SE352643B (de) 1973-01-08
NO131388C (de) 1975-05-21
IT1061759B (it) 1983-04-30
FI47109B (de) 1973-05-31
SE382990B (sv) 1976-02-23
DE1966427C3 (de) 1980-03-13
FR2001977A1 (en) 1969-10-03
NO131387B (de) 1975-02-10
JPS4833386B1 (de) 1973-10-13
NL6902045A (de) 1969-08-19
NO131386C (de) 1975-05-21
AT297218B (de) 1972-03-10
SU404195A3 (de) 1973-10-26
DE1966428B2 (de) 1977-07-21
JPS5622278B1 (de) 1981-05-23
IE32962B1 (en) 1974-02-06
NO131387C (de) 1975-05-21
CS155970B2 (de) 1974-06-24
CH538540A (de) 1973-08-15
AT300198B (de) 1972-07-10
NO131386B (de) 1975-02-10
CA941769A (en) 1974-02-12
FR2001977B1 (de) 1974-08-30
BE727506A (de) 1969-07-01
DE1966428C3 (de) 1978-03-02

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Legal Events

Date Code Title Description
PL Patent ceased