CH401960A - Verfahren zur Herstellung von 3-Keto- 4,6-6-trifluormethylsteroiden - Google Patents

Verfahren zur Herstellung von 3-Keto- 4,6-6-trifluormethylsteroiden

Info

Publication number
CH401960A
CH401960A CH668161A CH668161A CH401960A CH 401960 A CH401960 A CH 401960A CH 668161 A CH668161 A CH 668161A CH 668161 A CH668161 A CH 668161A CH 401960 A CH401960 A CH 401960A
Authority
CH
Switzerland
Prior art keywords
sep
trifluoromethyl
keto
steroids
series
Prior art date
Application number
CH668161A
Other languages
German (de)
English (en)
Inventor
Ole Godtfredsen Wagn
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of CH401960A publication Critical patent/CH401960A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH668161A 1960-06-08 1961-06-08 Verfahren zur Herstellung von 3-Keto- 4,6-6-trifluormethylsteroiden CH401960A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2019060 1960-06-08

Publications (1)

Publication Number Publication Date
CH401960A true CH401960A (de) 1965-11-15

Family

ID=10141901

Family Applications (1)

Application Number Title Priority Date Filing Date
CH668161A CH401960A (de) 1960-06-08 1961-06-08 Verfahren zur Herstellung von 3-Keto- 4,6-6-trifluormethylsteroiden

Country Status (3)

Country Link
CH (1) CH401960A (da)
DK (1) DK102857C (da)
ES (1) ES268064A1 (da)

Also Published As

Publication number Publication date
ES268064A1 (es) 1961-11-16
DK102857C (da) 1965-10-18

Similar Documents

Publication Publication Date Title
DE1253708B (de) Verfahren zur Herstellung von delta 16-20-Ketosteroiden
EP0042606B1 (de) Verfahren zur Herstellung von 17 Alpha-Hydroxy- und 17a Alpha-Hydroxy-D-homo-etiocarbonsäuren
CH401960A (de) Verfahren zur Herstellung von 3-Keto- 4,6-6-trifluormethylsteroiden
DE1793633C3 (de) Verfahren zur Herstellung von Gona 4(5),9(10)dien3 onen Ausscheidung aus 1468642
NO140458B (no) Metallpulver til bruk ved termisk spraying samt fremgangsmaate for fremstilling derav
DE1468864C3 (de) Verfahren zur Herstellung von 6 beta, 19-bzw. 11 beta, 18-Oxidosteroiden oder 18,11 beta-Jodhydrinen bzw. 18-Jod-llketonen
DE1190936B (de) Verfahren zur Herstellung von 3-Keto-delta-6-trifluormethylsteroiden bzw. 3-Keto-deltifluormethylsteroiden der Androstan- oder Pregnanreihe
DE1807585C3 (de) 14,15beta-Epoxycardenolide, Verfahren zu deren Herstellung und diese enthaltende Mittel
AT241705B (de) Verfahren zur Herstellung von neuen, ungesättigten Halogensteroiden
AT242871B (de) Verfahren zur Herstellung von neuen 3-Keto-Δ<4,6>-6-trifluormethylsteroiden und 3-Keto-Δ<1,4,6>-6-trifluormethylsteroiden
DE1668690C3 (de) Verfahren zur Herstellung von N-substituierten 4-Aminosteroiden der Androstan-Pregnan- und Cholestanreihe
DE3426771C2 (de) 13alpha-Methylgonane, deren Herstellung und Verwendung
DE1668687C3 (de) Neue 1 8-Methyt-Salpha-H-androstane, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
AT249865B (de) Verfahren zur Herstellung neuer Pyrazolverbindungen der Pregnanreihe
AT233184B (de) Verfahren zur Herstellung von 3-Oxo-Δ<1,4>-steroiden
CH500958A (de) Verfahren zur Herstellung von Steroidverbindungen
AT267088B (de) Verfahren zur Herstellung neuer 1,2α-Methylen-19-nor-testosterone
DE1468988C (de) nalpha-Chloräthinyl-lSbeta-äthyl-4-oder-5( 10)- gonen-3 -ketone.'
DE1180743B (de) Verfahren zur Dehydrierung von 3-Ketosteroiden
DE1114487B (de) Verfahren zur Herstellung von 6a, 6a-Dichlor-6,7-methylen- und 6a, 6a-Dibrom-6,7-methylenverbindungen von í¸-3-Ketosteroiden der Androstan- und Pregnanreihe
DE1243682B (de) Verfahren zur Herstellung von therapeutisch wirksamen Steroidverbindungen
CH390910A (de) Verfahren zur Herstellung von 19-Nor- 5-androsten-3B,17B-diolen
DE1668687B2 (de) Neue 18-methyl-5alpha-h-androstane, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel
DE1101415B (de) Verfahren zur Herstellung von 6ª‡-Methyl-17ª‡-acetoxy-4-pregnen-3, 20-dion
CH497409A (de) Verfahren zur Herstellung von Steroidverbindungen der Pregnanreihe