CH309097A - Process for the preparation of a bactericidal salicylanilide. - Google Patents
Process for the preparation of a bactericidal salicylanilide.Info
- Publication number
- CH309097A CH309097A CH309097DA CH309097A CH 309097 A CH309097 A CH 309097A CH 309097D A CH309097D A CH 309097DA CH 309097 A CH309097 A CH 309097A
- Authority
- CH
- Switzerland
- Prior art keywords
- salicylanilide
- bactericidal
- preparation
- dichloro
- mol
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Verfahren zur Herstellung eines bakteriziden Salieylanilides Gegenstand des vorliegenden Patentes ist ein Verfahren zur Herstellung eines bakteri ziden Salicylanilides. Das Verfahren ist da durch gekennzeichnet, dass man 1 Mol 4,5-Di- elilor-salicylsäure auf 1 Mol 2,5-Dichlor-anilin einwirken lä.sst.
Die erhaltene neue Verbindung, das 4,5-Dichlor-salieylsäure-2',5'-dichlor - anilid, schmilzt bei 222-223 . Sie soll als Desinfek tionsmittel für nichtarzneiliche Zwecke Ver wendung finden.
Beispiel 21 Teile 4,5-Dichlor-salieylsäure und 16 Teile 2,5-Diehlor-anilin werden in 400 Teilen Chlorbenzol gelöst und 0,5 Teile Aluminium chlorid und 6 Teile Phosphortrichlorid zuge geben. Diese Suspension wird so lange zum Sieden erhitzt, bis kein Chlorwasserstoff mehr entweicht, was nach ungefähr 2-3 Stunden der Fall ist. Die chlorbenzolische Lösung wird dann mit Wasser vermischt und mit Soda brillantalkalisch gestellt. Das Chlorbenzol wird mit Wasserdampf abgeblasen und der Destillationsrückstand aus Eisessig umkristal lisiert. Das neue Anilid schmilzt bei 222 bis 223 .
Process for the preparation of a bactericidal salieylanilide The present patent is a process for the preparation of a bactericidal salicylanilide. The process is characterized in that 1 mol of 4,5-di-elilor-salicylic acid is allowed to act on 1 mol of 2,5-dichloro-aniline.
The new compound obtained, 4,5-dichloro-salicic acid-2 ', 5'-dichloro-anilide, melts at 222-223. It should be used as a disinfectant for non-medicinal purposes.
Example 21 parts of 4,5-dichloro-salicic acid and 16 parts of 2,5-diehloro-aniline are dissolved in 400 parts of chlorobenzene and 0.5 part of aluminum chloride and 6 parts of phosphorus trichloride are added. This suspension is heated to the boil until no more hydrogen chloride escapes, which is the case after about 2-3 hours. The chlorobenzene solution is then mixed with water and made brilliantly alkaline with soda. The chlorobenzene is blown off with steam and the distillation residue is recrystallized from glacial acetic acid. The new anilide melts at 222 to 223.
Claims (1)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH304558T | 1951-12-29 | ||
| CH309097T | 1952-01-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH309097A true CH309097A (en) | 1955-08-15 |
Family
ID=25734863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH309097D CH309097A (en) | 1951-12-29 | 1952-01-03 | Process for the preparation of a bactericidal salicylanilide. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH309097A (en) |
-
1952
- 1952-01-03 CH CH309097D patent/CH309097A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CH309097A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH309098A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307880A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307881A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307884A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307888A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307878A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307879A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307883A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307891A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307889A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307882A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307886A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307892A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307890A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307887A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH307885A (en) | Process for the preparation of a bactericidal salicylanilide. | |
| CH240160A (en) | Process for the preparation of a basic ester of a 1-aryl-cycloalkyl-1-carboxylic acid. | |
| CH240162A (en) | Process for the preparation of a basic ester of a 1-aryl-cycloalkyl-1-carboxylic acid. | |
| CH240163A (en) | Process for the preparation of a basic ester of a 1-aryl-cycloalkyl-1-carboxylic acid. | |
| CH131288A (en) | Process for the preparation of a polysulfide ester of an aromatic carboxylic acid. | |
| CH242288A (en) | Process for the preparation of a basic ester of a 1-aryl-cycloalkyl-1-carboxylic acid. | |
| CH240168A (en) | Process for the preparation of a basic ester of a 1-aryl-cycloalkyl-1-carboxylic acid. | |
| CH240143A (en) | Process for the preparation of a basic aralkyl ether. | |
| CH240165A (en) | Process for the preparation of a basic ester of a 1-aryl-cycloalkyl-1-carboxylic acid. |