CH307891A - Process for the preparation of a bactericidal salicylanilide. - Google Patents

Process for the preparation of a bactericidal salicylanilide.

Info

Publication number
CH307891A
CH307891A CH307891DA CH307891A CH 307891 A CH307891 A CH 307891A CH 307891D A CH307891D A CH 307891DA CH 307891 A CH307891 A CH 307891A
Authority
CH
Switzerland
Prior art keywords
salicylanilide
bactericidal
preparation
methyl
chloro
Prior art date
Application number
Other languages
German (de)
Inventor
Ag J R Geigy
Original Assignee
Ag J R Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ag J R Geigy filed Critical Ag J R Geigy
Publication of CH307891A publication Critical patent/CH307891A/en

Links

Description

  

  Verfahren     zur    Herstellung eines     bakteriziden        Salieylanilides.       Gegenstand vorliegenden Patentes ist ein  Verfahren zur Herstellung eines bakteriziden       Salicylanilides.    Das Verfahren ist dadurch  gekennzeichnet, dass man 1     Mol        4-Methyl-5-          ehlor-salicylsäure    auf 1     Mol        3,4,5-Triehlor-          anilin    einwirken lässt.  



  Die erhaltene neue Verbindung, das     4-          Methyl    - 5     -,chlort-palieylsäure-3',4',5'    =     triehlor-          anilid,    schmilzt bei 275-276 . Sie soll als  Desinfektionsmittel für nicht arzneiliche  Zwecke Verwendung finden.  



  <I>Beispiel:</I>  47 Teile     4-Methyl-5-chlor-salicylsäure    und  50 Teile     3,4,5-Trichlor-anilin    werden in 450  Teilen Chlorbenzol gelöst und ein Teil Alu  miniumchlorid und 15 Teile     Phosphortrichlo-          rid    zugegeben. Diese Suspension wird so lange  zum Sieden erhitzt, bis kein Chlorwasserstoff  
EMI0001.0020     
  
    mehr <SEP> entweicht, <SEP> was <SEP> nach <SEP> ungefähr <SEP> 2       der Fall ist, Die     -eh#orbenzolische    Lösung  wird dann mit Wasser vermischt     und    mit  Soda brillantalkalisch gestellt.

   Das Chlor  benzol wird mit Wasserdampf abgeblasen und  der     Destillationsrückstand,    nach dem     Abfil-          trieren    und Trocknen, aus Chlorbenzol um  kristallisiert. Das erhaltene     4-Methyl.-5-chlor-          salicylsäure-3',4',5'-trichlor-a.nilid        schmilzt    bei  275-276 .



  Process for the preparation of a bactericidal salieylanilide. The present patent relates to a process for the preparation of a bactericidal salicylanilide. The process is characterized in that 1 mol of 4-methyl-5-chlorosalicylic acid is allowed to act on 1 mol of 3,4,5-triehloraniline.



  The new compound obtained, 4-methyl-5 -, chloro-palieylic acid-3 ', 4', 5 '= triehloranilide, melts at 275-276. It should be used as a disinfectant for non-medicinal purposes.



  <I> Example: </I> 47 parts of 4-methyl-5-chloro-salicylic acid and 50 parts of 3,4,5-trichloro-aniline are dissolved in 450 parts of chlorobenzene and one part of aluminum chloride and 15 parts of phosphorus trichloride are added . This suspension is heated to the boil until there is no hydrogen chloride
EMI0001.0020
  
    more <SEP> escapes, <SEP> what <SEP> is about <SEP> 2 after <SEP>, the -herbenzolic solution is then mixed with water and made brilliantly alkaline with soda.

   The chlorobenzene is blown off with steam and the distillation residue is recrystallized from chlorobenzene after it has been filtered off and dried. The 4-methyl.-5-chlorosalicylic acid-3 ', 4', 5'-trichloro-a.nilide obtained melts at 275-276.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines bakteri ziden Salicylanilides, dadurch gekennzeich net, dass man 1 Mol 4-Methyl-5-chlor-salicyl- säure auf 1 Mol 3,4,5-Tricblor-anilin ein wirken lässt. Die erhaltene neue Verbindung, das 4- Methyl- 5-,chlor-.salicylsäure-3',4',5'- trichlor- anilid, schmilzt bei 275-276 . PATENT CLAIM: Process for the production of a bacteriocidal salicylanilide, characterized in that 1 mol of 4-methyl-5-chloro-salicylic acid is allowed to act on 1 mol of 3,4,5-tricbloro-aniline. The new compound obtained, 4-methyl-5-, chloro-salicylic acid-3 ', 4', 5'-trichloroanilide, melts at 275-276.
CH307891D 1951-12-29 1951-12-29 Process for the preparation of a bactericidal salicylanilide. CH307891A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH304558T 1951-12-29
CH307891T 1951-12-29

Publications (1)

Publication Number Publication Date
CH307891A true CH307891A (en) 1955-06-15

Family

ID=25734860

Family Applications (1)

Application Number Title Priority Date Filing Date
CH307891D CH307891A (en) 1951-12-29 1951-12-29 Process for the preparation of a bactericidal salicylanilide.

Country Status (1)

Country Link
CH (1) CH307891A (en)

Similar Documents

Publication Publication Date Title
CH307891A (en) Process for the preparation of a bactericidal salicylanilide.
CH307888A (en) Process for the preparation of a bactericidal salicylanilide.
CH307878A (en) Process for the preparation of a bactericidal salicylanilide.
CH307889A (en) Process for the preparation of a bactericidal salicylanilide.
CH307890A (en) Process for the preparation of a bactericidal salicylanilide.
CH307880A (en) Process for the preparation of a bactericidal salicylanilide.
CH307892A (en) Process for the preparation of a bactericidal salicylanilide.
CH307881A (en) Process for the preparation of a bactericidal salicylanilide.
CH307882A (en) Process for the preparation of a bactericidal salicylanilide.
CH307879A (en) Process for the preparation of a bactericidal salicylanilide.
CH307886A (en) Process for the preparation of a bactericidal salicylanilide.
CH307884A (en) Process for the preparation of a bactericidal salicylanilide.
CH307887A (en) Process for the preparation of a bactericidal salicylanilide.
CH307883A (en) Process for the preparation of a bactericidal salicylanilide.
CH309097A (en) Process for the preparation of a bactericidal salicylanilide.
CH307885A (en) Process for the preparation of a bactericidal salicylanilide.
CH309098A (en) Process for the preparation of a bactericidal salicylanilide.
CH312531A (en) Process for making a pyridazone.
CH310734A (en) Process for the preparation of a bactericidal salicylanilide.
CH310733A (en) Process for the preparation of a bactericidal salicylanilide.
CH310732A (en) Process for the preparation of a bactericidal salicylanilide.
CH245679A (en) Process for the preparation of a 4-chloro-benzenesulfonamide.
CH269082A (en) Process for the preparation of a diaryl-butenyl-amine.
CH120430A (en) Process for the preparation of a new sulfur- and nitrogen-containing condensation product from the action product of chlorosulfur on a-naphthylamine.
CH309468A (en) Process for the preparation of a salicylanilide.