CH131250A - Process for the preparation of m-Oxy-N-methyldiethylaminoethylaniline. - Google Patents

Process for the preparation of m-Oxy-N-methyldiethylaminoethylaniline.

Info

Publication number
CH131250A
CH131250A CH131250DA CH131250A CH 131250 A CH131250 A CH 131250A CH 131250D A CH131250D A CH 131250DA CH 131250 A CH131250 A CH 131250A
Authority
CH
Switzerland
Prior art keywords
methyldiethylaminoethylaniline
oxy
preparation
resorcinol
methyldiethylethylenediamine
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH131250A publication Critical patent/CH131250A/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

  Verfahren zur Darstellung von     m-Ogy-N-metliyldiä,thylaminoäthylanilin.       Es wurde gefunden, dass man     m-Oxy-N-          methyldiäthylaminoäthylanilin    erhält, wenn  man     Resorcin    und     as-Methyldiäthyläthylendi-          amin    miteinander erhitzt.  



  Die neue Verbindung siedet unter 0,5 mm  Druck bei<B>1510</B> C; sie hat eine hervorragend  verbessernde Wirkung auf Atmung und Herz  tätigkeit und soll pharmazeutische Verwen  dung finden sowie als Zwischenprodukt für  die Herstellung analoger Derivate.  
EMI0001.0007     
    110 g     Resorcin    und 130 g des     as-Methyl-          diäthyläthylendiamins    werden mehrere Stun  den auf zirka 200   im Ölbad erhitzt.  



  Durch Ausziehen der Reaktionsmasse mit  verdünnter Salzsäure trennt man von unver  ändertem     Resorcin,    durch     Alkalischmachen     und     Ausäthern    von     Diamino-Verbindungen.       Ansäuern der     alkälischen    Lösung, Zufügen  von Pottasche und     Ausäthern    ergibt das       m-Oxy-N-methyldiäthylaminoäthylanilin    vom  Siedepunkt<B>1510</B> bei 0,5 mm.  



  Diese Verbindung zeigt eine hervorragend  verbessernde Wirkung auf Atmung und Herz  tätigkeit.



  Process for the preparation of m-Ogy-N-metliyldiä, thylaminoäthylanilin. It has been found that m-oxy-N-methyldiethylaminoethylaniline is obtained when resorcinol and as-methyldiethylethylenediamine are heated together.



  The new compound boils under 0.5 mm pressure at <B> 1510 </B> C; it has an outstandingly improving effect on respiration and cardiac activity and is intended to be used in pharmaceuticals and as an intermediate for the production of analogous derivatives.
EMI0001.0007
    110 g of resorcinol and 130 g of as-methyl diethylethylenediamine are heated for several hours to about 200 in an oil bath.



  Unchanged resorcinol is separated by extracting the reaction mass with dilute hydrochloric acid, and diamino compounds are separated by making them alkaline and etherifying them. Acidification of the alkaline solution, addition of potash and ethers gives the m-oxy-N-methyldiethylaminoethylaniline with a boiling point of <B> 1510 </B> at 0.5 mm.



  This compound shows an excellent beneficial effect on breathing and heart activity.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von m-Oxy-N- methyldiäthylaminoäthylanilin, dadurch ge kennzeichnet, dass man Resorcin und as-Me- thyldiäthyläthylendiamin miteinander erhitzt. Die neue Verbindung siedet unter 0,5 mm Druck bei 151 C; sie hat eine hervorragend verbessernde Wirkung auf Atmung und Herz tätigkeit und soll pharmazeutische Verwen dung finden sowie als Zwischenprodukt für die Herstellung analoger Derivate. PATENT CLAIM: Process for the preparation of m-oxy-N-methyldiethylaminoethylaniline, characterized in that resorcinol and as-methyldiethylethylenediamine are heated together. The new compound boils under 0.5 mm pressure at 151 C; it has an outstandingly improving effect on respiration and cardiac activity and is intended to be used in pharmaceuticals and as an intermediate for the production of analogous derivatives.
CH131250D 1926-07-08 1927-07-07 Process for the preparation of m-Oxy-N-methyldiethylaminoethylaniline. CH131250A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE131250X 1926-07-08
CH129424T 1927-07-07

Publications (1)

Publication Number Publication Date
CH131250A true CH131250A (en) 1929-01-31

Family

ID=25711253

Family Applications (1)

Application Number Title Priority Date Filing Date
CH131250D CH131250A (en) 1926-07-08 1927-07-07 Process for the preparation of m-Oxy-N-methyldiethylaminoethylaniline.

Country Status (1)

Country Link
CH (1) CH131250A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2618657A (en) * 1952-11-18 Process o

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2618657A (en) * 1952-11-18 Process o

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