CH175810A - Process for obtaining a therapeutically valuable product. - Google Patents

Process for obtaining a therapeutically valuable product.

Info

Publication number
CH175810A
CH175810A CH175810DA CH175810A CH 175810 A CH175810 A CH 175810A CH 175810D A CH175810D A CH 175810DA CH 175810 A CH175810 A CH 175810A
Authority
CH
Switzerland
Prior art keywords
chloro
obtaining
therapeutically valuable
valuable product
hexyl
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH175810A publication Critical patent/CH175810A/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

  

  Verfahren zur Gewinnung eines therapeutisch wertvollen Produktes.    Gegenstand vorliegenden Patentes ist ein  Verfahren zur Darstellung von     6-Chlor-4-(n-          liexyl-1')-resorcin.    Das Verfahren ist dadurch  gekennzeichnet, dass man     6-Chlor-4-(n-hexylyl)-          resorcin    mit einem reduzierenden Mittel zum       6-Chlor-4-(n-hexyl-1')-resorcin    reduziert. Die  Reaktion erfolgt zweckmässig durch Behand  lung des     6-Chlor-4-(n-hexylyl)-resorcins    mit  amalgamiertem Zink und Salzsäure.

   Das so  erhältliche     6-Chlor-4-(ii-hexyl-1')-resorein    sie  det unter 5-6 mm Druck bei     170-173'.     Es ist schwer löslich in Wasser, löst sich  aber in Natronlauge und in organischen  Lösemitteln. Das neue Produkt soll thera  peutische Anwendung finden.  



  <I>Beispiel:</I>  100     gr        6-Chlor-4-(n-hexylyl)-resorein        (Kpbb          175-180')    werden mit 300     gr    amalgamier  tem Zink, 600 cm' konzentrierter Salzsäure,  150     cm3    Eisessig und 200 cm' Wasser am       Rückflusskühler    7 Stunden bis zum Ausbleiben  der     Eisenchloridreaktion    kräftig     gekocht.    Als  dann wird warm von der wässerigen Lösung    getrennt, mit heisser     Natriumcliloridlösung     kongoneutral gewaschen und destilliert. Das       6-Chlor-4-(n-hexyl-1')-resorcin    siedet bei 170  bis 173   unter 5-6 mm Druck.

   Es ist  schwer löslich in Wasser und leicht löslich in  organischen Lösemitteln.



  Process for obtaining a therapeutically valuable product. The present patent is a process for the preparation of 6-chloro-4- (n-liexyl-1 ') - resorcinol. The process is characterized in that 6-chloro-4- (n-hexylyl) - resorcinol is reduced with a reducing agent to 6-chloro-4- (n-hexyl-1 ') - resorcinol. The reaction is expediently carried out by treating the 6-chloro-4- (n-hexylyl) resorcinol with amalgamated zinc and hydrochloric acid.

   The 6-chloro-4- (ii-hexyl-1 ') - resorein obtainable in this way is under 5-6 mm pressure at 170-173'. It is sparingly soluble in water, but it dissolves in caustic soda and organic solvents. The new product is intended to be used therapeutically.



  <I> Example: </I> 100 grams of 6-chloro-4- (n-hexylyl) -resorein (Kpbb 175-180 ') are mixed with 300 grams of amalgamated zinc, 600 cm' of concentrated hydrochloric acid, 150 cm3 of glacial acetic acid and 200 cm 'water was boiled vigorously on the reflux condenser for 7 hours until the iron chloride reaction did not occur. Then the warm is separated from the aqueous solution, washed with hot sodium chloride solution and distilled. The 6-chloro-4- (n-hexyl-1 ') - resorcinol boils at 170 to 173 under 5-6 mm pressure.

   It is sparingly soluble in water and easily soluble in organic solvents.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von 6-Chlor- 4-(n-hexyl-1')-resoroin, dadurch gekennzeich net, dass man 6-Chlor-4-(n-hexylyl-resorein mit einem Reduktionsmittel behandelt. Das so erhältliche 6-Chlor-4-(n-hexyl-1')- resorcin siedet unter 5-6 mm Druck bei 170-1730. UNTERANSPRUCH: Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass als Reduktionsmittel amalgamiertes Zink und konzentrierte Salz säure verwendet wird. PATENT CLAIM: Process for the preparation of 6-chloro-4- (n-hexyl-1 ') - resoroin, characterized in that 6-chloro-4- (n-hexylyl-resorein is treated with a reducing agent -Chlor-4- (n-hexyl-1 ') - resorcinol boils under 5-6 mm pressure at 170-1730. SUBSTANTIAL CLAIM: Process according to patent claim, characterized in that amalgamated zinc and concentrated hydrochloric acid are used as reducing agents.
CH175810D 1932-02-29 1933-02-21 Process for obtaining a therapeutically valuable product. CH175810A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE175810X 1932-02-29

Publications (1)

Publication Number Publication Date
CH175810A true CH175810A (en) 1935-03-15

Family

ID=5694853

Family Applications (1)

Application Number Title Priority Date Filing Date
CH175810D CH175810A (en) 1932-02-29 1933-02-21 Process for obtaining a therapeutically valuable product.

Country Status (1)

Country Link
CH (1) CH175810A (en)

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