CH161481A - Process for the preparation of 2,3-dimethylindole-6-sulfonic acid. - Google Patents

Process for the preparation of 2,3-dimethylindole-6-sulfonic acid.

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Publication number
CH161481A
CH161481A CH161481DA CH161481A CH 161481 A CH161481 A CH 161481A CH 161481D A CH161481D A CH 161481DA CH 161481 A CH161481 A CH 161481A
Authority
CH
Switzerland
Prior art keywords
dimethylindole
sulfonic acid
preparation
condensation
acid
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH161481A publication Critical patent/CH161481A/en

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  • Indole Compounds (AREA)

Description

  

  Verfahren zur Darstellung der     2.3-Dimethylindol-6-sulfonsäure.       Es wurde     (yefunden,    dass man die 2.3  1.)imethylindol-6-sulfosäure erhält, wenn man       m-Phenylhydrazinsulfosäure    mit     Methyl-          äthylketon    kondensiert. Als Kondensations  mittel kann man hierbei die bekannten Kon  densationsmittel anwenden: beispielsweise  Eisessig. Man kann aber auch in neutraler  Lösung arbeiten oder in schwachsaurer, wie  verdünnter Essigsäure. Das neue Produkt  kristallisiert in Form des     Natriumsalzes    in  kleinen weissen     Kriställchen.    Es soll als  Zwischenprodukt bei der Herstellung von  Farbstoffen Verwendung finden.  



       Beispiel:     19 kg     m-Phenylhydrazinsulfosäure    wer  den in 100 Liter Wasser mit 7,5 kg     Methyl-          äthylketon    bei 90 bis 95   einige Stunden er  hitzt. Nach Beendigung der Reaktion fügt  man Natronlauge hinzu und erhält nach Ab  kühlen die     2.3-Dimethylindol-6-sulfosäure     als     Natriumsalz.    Man erhält ähnlich gute  Ausbeuten, wenn man in Alkohol oder in    verdünnter Essigsäure arbeitet. Arbeitet plan  in Eisessig, so kann man zur Kondensation  auch die Salze der     Phenylhydrazinsulfo-          säuren    verwenden.



  Process for the preparation of 2,3-dimethylindole-6-sulfonic acid. It has been found that the 2.3 1.) imethylindole-6-sulfonic acid is obtained when m-phenylhydrazine sulfonic acid is condensed with methyl ethyl ketone. The known condensation agents can be used here as condensation agents: for example glacial acetic acid. But you can also work in neutral solution or in weakly acidic, such as dilute acetic acid. The new product crystallizes in the form of the sodium salt in small white crystals. It is said to be used as an intermediate in the manufacture of dyes.



       Example: 19 kg of m-phenylhydrazinesulphonic acid in 100 liters of water with 7.5 kg of methyl ethyl ketone at 90 to 95 for a few hours. After the reaction has ended, sodium hydroxide solution is added and, after cooling, the 2,3-dimethylindole-6-sulfonic acid is obtained as the sodium salt. Similar good yields are obtained if one works in alcohol or in dilute acetic acid. If you work in glacial acetic acid, you can also use the salts of phenylhydrazine sulfonic acids for condensation.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von 2.3-Di- methylindol-6-sulfosäure, dadurch gekenn zeichnet, dass man m-Phenylhydrazinsulfo- säure mit Methyläthylketon kondensiert. Das neue Produkt kristallisiert in Form des Natriumsalzes in kleinen weissen Kriställ- chen. UNTERANSPRÜCHE: 1.. Verfahren nach Patentanspruch, dadurch gekennzeichnet,dass man die Kondensation in saurer Lösung vornimmt. 2. PATENT CLAIM: Process for the preparation of 2,3-dimethylindole-6-sulfonic acid, characterized in that m-phenylhydrazinesulfonic acid is condensed with methyl ethyl ketone. The new product crystallizes in the form of the sodium salt in small white crystals. SUBClaims: 1 .. Method according to claim, characterized in that the condensation is carried out in acidic solution. 2. Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man die Kondensation in neutraler Lösung vornimmt. Process according to patent claim, characterized in that the condensation is carried out in a neutral solution.
CH161481D 1931-03-19 1932-02-18 Process for the preparation of 2,3-dimethylindole-6-sulfonic acid. CH161481A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE161481X 1931-03-19
CH159149T 1932-02-18

Publications (1)

Publication Number Publication Date
CH161481A true CH161481A (en) 1933-04-30

Family

ID=25717199

Family Applications (1)

Application Number Title Priority Date Filing Date
CH161481D CH161481A (en) 1931-03-19 1932-02-18 Process for the preparation of 2,3-dimethylindole-6-sulfonic acid.

Country Status (1)

Country Link
CH (1) CH161481A (en)

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