CA3111193A1 - Salts and crystal forms of gabaa positive allosteric modulator - Google Patents
Salts and crystal forms of gabaa positive allosteric modulator Download PDFInfo
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- CA3111193A1 CA3111193A1 CA3111193A CA3111193A CA3111193A1 CA 3111193 A1 CA3111193 A1 CA 3111193A1 CA 3111193 A CA3111193 A CA 3111193A CA 3111193 A CA3111193 A CA 3111193A CA 3111193 A1 CA3111193 A1 CA 3111193A1
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- 239000013078 crystal Chemical group 0.000 title description 22
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- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
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- Pyridine Compounds (AREA)
- Steroid Compounds (AREA)
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| PCT/US2019/049103 WO2020047434A1 (en) | 2018-08-31 | 2019-08-30 | Salts and crystal forms of gabaa positive allosteric modulator |
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| US10562930B1 (en) | 2018-08-31 | 2020-02-18 | Praxis Precision Medicines, Inc. | Salts and crystal forms of GABAA positive allosteric modulator |
| KR20210149028A (ko) * | 2018-12-14 | 2021-12-08 | 프락시스 프리시젼 메디신즈, 인크. | 우울증의 치료 방법 |
| EP4125921A1 (en) | 2020-03-25 | 2023-02-08 | Sage Therapeutics, Inc. | Use of agents for treatment of respiratory conditions |
| WO2022006541A1 (en) * | 2020-07-02 | 2022-01-06 | Praxis Precision Medicines, Inc. | Methods for the treatment of adjustment disorder |
| US20240148756A1 (en) | 2021-02-18 | 2024-05-09 | Sage Therapeutics, Inc. | Use of neuroactive steroid for treatment of sexual dysfunction |
| EP4294819A4 (en) * | 2021-02-18 | 2024-12-18 | Praxis Precision Medicines, Inc. | GABA-A POSITIVE ALLOSTERIC MODULATOR HEMI-CITRATE SALTS AND CORRESPONDING CRYSTALLINE FORM |
| WO2022231309A1 (ko) | 2021-04-27 | 2022-11-03 | 경북대학교 산학협력단 | 저분자 콜라겐을 유효성분으로 포함하는 근감소증의 예방 또는 개선용 식품 조성물 및 약학적 조성물 |
| WO2023159035A1 (en) | 2022-02-16 | 2023-08-24 | Sage Therapeutics, Inc. | Neuroactive steroids for treatment of cns-related disorders |
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| US5939545A (en) | 1994-02-14 | 1999-08-17 | Cocensys, Inc. | Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series |
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| EP3885352B1 (en) * | 2014-10-16 | 2024-11-27 | Sage Therapeutics, Inc. | A compound, compositions thereof and this compound for use in methods of treating cns disorders |
| TWI777515B (zh) | 2016-08-18 | 2022-09-11 | 美商愛戴爾製藥股份有限公司 | 治療嗜伊紅性食道炎之方法 |
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| US10562930B1 (en) | 2018-08-31 | 2020-02-18 | Praxis Precision Medicines, Inc. | Salts and crystal forms of GABAA positive allosteric modulator |
| KR20210149028A (ko) | 2018-12-14 | 2021-12-08 | 프락시스 프리시젼 메디신즈, 인크. | 우울증의 치료 방법 |
| KR20210105934A (ko) | 2018-12-17 | 2021-08-27 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 유기 화합물 |
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| MX2022004022A (es) | 2019-10-02 | 2022-05-18 | Praxis Prec Medicines Inc | Combinaciones de moduladores alostericos positivos del receptor de gaba-a y antagonistas de nmda, moduladores alostericos negativos de nmda o agonistas parciales de nmda. |
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| EP4200312A4 (en) | 2020-08-20 | 2024-09-25 | Intra-Cellular Therapies, Inc. | ORGANIC COMPOUNDS |
| EP4294819A4 (en) | 2021-02-18 | 2024-12-18 | Praxis Precision Medicines, Inc. | GABA-A POSITIVE ALLOSTERIC MODULATOR HEMI-CITRATE SALTS AND CORRESPONDING CRYSTALLINE FORM |
| TW202308653A (zh) | 2021-04-26 | 2023-03-01 | 美商普雷西斯精密藥品股份有限公司 | 以神經活性類固醇進行治療的方法 |
| WO2023159094A2 (en) | 2022-02-16 | 2023-08-24 | Praxis Precision Medicines, Inc. | PROCESS OF MAKING 3α-HYDROXY-3β-METHOXYMETHYL-21-(1'- IMIDAZOLYL)-5α-PREGNAN-20-ONE |
| US20250345345A1 (en) | 2022-04-26 | 2025-11-13 | Praxis Precision Medicines, Inc. | Methods for the treatment of neurological disorders |
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- 2019-11-27 US US16/698,057 patent/US10927141B2/en active Active
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2022
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2023
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2024
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