CA3069047A1 - A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (msi) cancers - Google Patents
A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (msi) cancers Download PDFInfo
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- CA3069047A1 CA3069047A1 CA3069047A CA3069047A CA3069047A1 CA 3069047 A1 CA3069047 A1 CA 3069047A1 CA 3069047 A CA3069047 A CA 3069047A CA 3069047 A CA3069047 A CA 3069047A CA 3069047 A1 CA3069047 A1 CA 3069047A1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- A61K39/0005—Vertebrate antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP17181026.0 | 2017-07-12 | ||
| EP17181026 | 2017-07-12 | ||
| PCT/EP2018/069032 WO2019012082A1 (en) | 2017-07-12 | 2018-07-12 | UNIVERSAL VACCINE BASED ON SHARED TUMOR NEO-ANTIGENS FOR THE PREVENTION AND TREATMENT OF MICRO-SATELLITE INSTABILITY CANCER (MSI) |
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| CA3069047A1 true CA3069047A1 (en) | 2019-01-17 |
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| CA3069047A Pending CA3069047A1 (en) | 2017-07-12 | 2018-07-12 | A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (msi) cancers |
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| PT (1) | PT3652606T (OSRAM) |
| SG (1) | SG11202000250PA (OSRAM) |
| WO (1) | WO2019012082A1 (OSRAM) |
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| EP3827263A1 (en) | 2018-07-26 | 2021-06-02 | Frame Pharmaceuticals B.V. | Cancer vaccines for colorectal cancer |
| WO2020022903A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | ARID1A, CDKN2A, KMT2B, KMT2D, TP53 and PTEN VACCINES FOR CANCER |
| CA3106567A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | Cancer vaccines for kidney cancer |
| EP3827261A1 (en) | 2018-07-26 | 2021-06-02 | Frame Pharmaceuticals B.V. | Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database |
| US20210187088A1 (en) | 2018-07-26 | 2021-06-24 | Frame Pharmaceuticals B.V. | Cancer vaccines for uterine cancer |
| CA3106564A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | Cancer vaccines for breast cancer |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| US20220008525A1 (en) * | 2019-02-07 | 2022-01-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Cancer specific frameshift vaccines |
| IL293051A (en) | 2019-11-18 | 2022-07-01 | Janssen Biotech Inc | Vaccines based on mutant calr and jak2 and their uses |
| WO2021228999A1 (en) * | 2020-05-12 | 2021-11-18 | Institut Curie | Neoantigenic epitopes associated with sf3b1 mutations |
| US12295997B2 (en) | 2020-07-06 | 2025-05-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| JP2024516542A (ja) * | 2021-04-06 | 2024-04-16 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | Ｍｈｃクラスｉペプチドを含む方法および組成物 |
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| US20060160090A1 (en) * | 2003-04-11 | 2006-07-20 | Macina Robert A | Composition splice variants and methods relating to cancer specific genes and proteins |
| CN1824325A (zh) * | 2005-12-16 | 2006-08-30 | 武汉大学 | 人乳头病毒dna嵌合疫苗及制备方法和应用 |
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2018
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- 2018-07-12 AU AU2018298849A patent/AU2018298849B2/en active Active
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| CN111328420B (zh) | 2023-07-25 |
| IL271966A (en) | 2020-02-27 |
| US20200222519A1 (en) | 2020-07-16 |
| FI3652606T3 (fi) | 2023-03-16 |
| KR102709778B1 (ko) | 2024-09-26 |
| BR112020000590A2 (pt) | 2020-07-14 |
| US11578109B2 (en) | 2023-02-14 |
| MX2020000413A (es) | 2020-09-28 |
| EP3652606B1 (en) | 2023-01-11 |
| JP7274223B2 (ja) | 2023-05-16 |
| RU2019144505A3 (OSRAM) | 2021-08-12 |
| HUE061840T2 (hu) | 2023-08-28 |
| WO2019012082A1 (en) | 2019-01-17 |
| IL271966B1 (en) | 2024-09-01 |
| RU2019144505A (ru) | 2021-08-12 |
| JP2020532288A (ja) | 2020-11-12 |
| IL271966B2 (en) | 2025-01-01 |
| AU2018298849B2 (en) | 2022-07-14 |
| EP3652606A1 (en) | 2020-05-20 |
| AU2018298849A1 (en) | 2020-01-02 |
| PT3652606T (pt) | 2023-03-16 |
| SG11202000250PA (en) | 2020-02-27 |
| CN111328420A (zh) | 2020-06-23 |
| KR20200029443A (ko) | 2020-03-18 |
| NZ759940A (en) | 2023-07-28 |
| DK3652606T3 (da) | 2023-03-13 |
| PL3652606T3 (pl) | 2023-04-24 |
| DK3652606T5 (da) | 2024-08-26 |
| ES2940087T3 (es) | 2023-05-03 |
| WO2019012082A9 (en) | 2019-05-02 |
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