CA3020393A1 - Chiral peptides - Google Patents
Chiral peptides Download PDFInfo
- Publication number
- CA3020393A1 CA3020393A1 CA3020393A CA3020393A CA3020393A1 CA 3020393 A1 CA3020393 A1 CA 3020393A1 CA 3020393 A CA3020393 A CA 3020393A CA 3020393 A CA3020393 A CA 3020393A CA 3020393 A1 CA3020393 A1 CA 3020393A1
- Authority
- CA
- Canada
- Prior art keywords
- amino acid
- orn
- phe
- peptide agent
- tetrameric peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662321168P | 2016-04-11 | 2016-04-11 | |
| US62/321,168 | 2016-04-11 | ||
| PCT/US2017/026869 WO2017180535A1 (en) | 2016-04-11 | 2017-04-10 | Chiral peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3020393A1 true CA3020393A1 (en) | 2017-10-19 |
Family
ID=60042852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3020393A Abandoned CA3020393A1 (en) | 2016-04-11 | 2017-04-10 | Chiral peptides |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10870678B2 (enExample) |
| EP (1) | EP3442990A4 (enExample) |
| JP (1) | JP2019523260A (enExample) |
| CN (1) | CN109563131A (enExample) |
| AU (2) | AU2017249218B2 (enExample) |
| CA (1) | CA3020393A1 (enExample) |
| WO (1) | WO2017180535A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7606966B2 (ja) | 2018-12-18 | 2024-12-26 | ステルス バイオセラピューティクス インコーポレイテッド | ミトコンドリア病を標的とするアナログ |
| KR20210093957A (ko) | 2018-12-18 | 2021-07-28 | 스텔스 바이오테라퓨틱스 코포레이션 | 미토콘드리아-표적화 펩타이드 |
| US12215173B2 (en) | 2019-08-07 | 2025-02-04 | HUMANWELL PHARMACEUTICAL US, Inc. | Kappa opioid receptor peptide amide ligands |
| US20210255196A1 (en) * | 2020-01-17 | 2021-08-19 | Waters Technologies Corporation | Low binding surfaces for peptide mapping |
| KR20220151628A (ko) * | 2020-03-06 | 2022-11-15 | 알레그로 파마슈티칼스, 엘엘씨 | 미토콘드리아 기능의 손상을 개선하거나 감소시키기 위한 치료 |
| AU2020454871A1 (en) | 2020-06-25 | 2023-01-19 | Humanwell Pharmaceutical US | Peptides for treatment of medical disorders |
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| CN104725472A (zh) | 2010-01-25 | 2015-06-24 | 康奈尔大学 | 芳香族阳离子肽及其用途 |
| WO2011106717A1 (en) | 2010-02-26 | 2011-09-01 | University Of Florida Research Foundation, Inc. | Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm dysfunction and skeletal muscle atrophy |
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| CN107496899A (zh) | 2011-09-29 | 2017-12-22 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| WO2013059071A1 (en) | 2011-10-17 | 2013-04-25 | Cornell University | Aromatic-cationic peptides and uses of same |
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| WO2013126775A1 (en) | 2012-02-23 | 2013-08-29 | Cornell University | Aromatic-cationic peptides and uses of same |
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| US20140034183A1 (en) | 2012-07-31 | 2014-02-06 | Viz Enterprises, Llc | Cap assembly for dispensing a dispensable component and method of making and using the same |
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| CN106163537A (zh) * | 2013-09-30 | 2016-11-23 | 康奈尔大学 | 心磷脂靶向肽抑制β‑淀粉样蛋白寡聚物毒性 |
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| EP3077049B1 (en) | 2013-12-02 | 2019-06-19 | Stealth BioTherapeutics Corp | Compositions for use in treating vitiligo |
| CN112457368A (zh) | 2013-12-27 | 2021-03-09 | 康德生物医疗技术公司 | 药学相关的芳香族阳离子肽 |
| EP2913287B1 (en) | 2014-02-26 | 2018-01-03 | Otis Elevator Company | Governor for controlling the speed of a hoisted object relative to a guide member |
| CA2942143A1 (en) | 2014-03-03 | 2015-09-11 | Stealth Biotherapeutics Corp | Pharmaceutically relevant aromatic-cationic peptides and methods of generating the same |
| WO2016004441A1 (en) | 2014-07-03 | 2016-01-07 | Stealth Peptides International, Inc. | Methods for the prevention or treatment of acute myocardial infarction injury |
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- 2017-04-10 WO PCT/US2017/026869 patent/WO2017180535A1/en not_active Ceased
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| AU2017249218A1 (en) | 2018-11-01 |
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