CA2979773A1 - Materials and methods for diagnosis and treatment of alzheimer's disease - Google Patents
Materials and methods for diagnosis and treatment of alzheimer's disease Download PDFInfo
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- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G—PHYSICS
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| GB201504432A GB201504432D0 (en) | 2015-03-17 | 2015-03-17 | Materials and methods for diagnosis and treatment of alzheimers disease |
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| PCT/EP2016/055883 WO2016146783A1 (en) | 2015-03-17 | 2016-03-17 | Materials and methods for diagnosis and treatment of alzheimer's disease |
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| GB201509134D0 (en) | 2015-05-28 | 2015-07-15 | Electrophoretics Ltd | Biomolecules involved in Alzheimer's disease |
| CA3070446A1 (en) | 2017-07-25 | 2019-01-31 | Immutics, Inc. | Treating cancer by blocking the interaction of tim-3 and its ligand |
| KR102034929B1 (ko) * | 2017-09-27 | 2019-10-22 | 한양대학교 산학협력단 | Nckap1 단백질 또는 상기 단백질을 암호화하는 유전자를 포함하는 신경계 퇴행성질환의 예방 또는 치료용 약학적 조성물 |
| KR102063610B1 (ko) * | 2018-05-23 | 2020-01-08 | 충북대학교 산학협력단 | 퇴행성 신경질환 진단용 신규한 바이오마커 및 이의 용도 |
| KR102232200B1 (ko) * | 2019-03-13 | 2021-03-25 | 아주대학교산학협력단 | 알츠하이머치매 진단 바이오마커 |
| US20220003787A1 (en) * | 2018-10-30 | 2022-01-06 | Ajou University Industry-Academic Cooperation Foundation | Biomarker proteins for diagnosing alzheimer's dementia and use thereof |
| KR101992060B1 (ko) * | 2018-10-30 | 2019-06-21 | 아주대학교산학협력단 | 알츠하이머치매 진단 체액 바이오마커 후보 단백4종 |
| CN109738653B (zh) * | 2019-01-11 | 2022-04-12 | 湖南诺琪生物科技有限公司 | 用于阿尔茨海默症的检测、诊断或风险预测的抗原蛋白组合以及包含其的试剂盒 |
| CN120058944A (zh) | 2019-01-30 | 2025-05-30 | 真和制药有限公司 | 抗gal3抗体及其用途 |
| CN110261272B (zh) * | 2019-07-05 | 2020-08-18 | 西南交通大学 | 基于地理探测和pca对pm2.5浓度分布的关键影响因子筛选方法 |
| CN112336859A (zh) * | 2019-08-06 | 2021-02-09 | 上海绿谷制药有限公司 | 通过抑制t细胞摄取氨基酸治疗阿尔茨海默病的方法 |
| KR20220104706A (ko) * | 2019-10-28 | 2022-07-26 | 에전 | 알츠하이머병의 침묵 단계를 진단하기 위한 바이오마커 및 이의 용도 |
| KR102313455B1 (ko) * | 2020-02-27 | 2021-10-15 | 이화여자대학교 산학협력단 | 알츠하이머병 경도인지장애의 진단 또는 알츠하이머병 치매로의 진행 위험성 예측 방법 |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| CN112695084A (zh) * | 2021-02-08 | 2021-04-23 | 山东大学第二医院 | 诊断阿尔茨海默病和阿尔茨海默病进展的生物标志物及应用 |
| GB202102399D0 (en) * | 2021-02-19 | 2021-04-07 | Univ Manchester | Methods of determining alzheimer's disease |
| US20250270618A1 (en) * | 2021-03-08 | 2025-08-28 | The Children's Medical Center Corporation | Methods for diagnosis and treatment of alzheimer's disease |
| US20230144446A1 (en) * | 2021-07-23 | 2023-05-11 | Cassava Sciences, Inc. | Blood-based diagnostic assays for alzheimer's disease |
| WO2023235871A2 (en) * | 2022-06-03 | 2023-12-07 | Seer, Inc. | Systems, compositions, and methods relating to neurodegenerative diseases |
| WO2024073067A2 (en) * | 2022-09-30 | 2024-04-04 | Mayo Foundation For Medical Education And Research | Assessing and treating tremor |
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| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| JPWO2004001865A1 (ja) | 2002-06-19 | 2005-10-27 | 株式会社東芝 | 熱電素子とそれを用いた電子部品モジュールおよび携帯用電子機器 |
| WO2005020784A2 (en) | 2003-05-23 | 2005-03-10 | Mount Sinai School Of Medicine Of New York University | Surrogate cell gene expression signatures for evaluating the physical state of a subject |
| WO2005019825A2 (en) * | 2003-08-20 | 2005-03-03 | Genova Ltd. | Secreted polypeptide species and use thereof |
| US7794948B2 (en) * | 2003-11-07 | 2010-09-14 | Vermilllion, Inc. | Biomarkers for alzheimer's disease |
| WO2006110621A2 (en) * | 2005-04-11 | 2006-10-19 | Cornell Research Foundation, Inc. | Multiplexed biomarkers for monitoring the alzheimer's disease state of a subject |
| ES2453106T3 (es) * | 2009-01-26 | 2014-04-04 | Electrophoretics Limited | Métodos de diagnóstico y pronóstico en relación con la enfermedad de Alzheimer |
| WO2010111587A1 (en) | 2009-03-26 | 2010-09-30 | Trustees Of The University Of Pennsylvania | Modulators of tdp-43 mediated toxicity |
| WO2011005893A2 (en) * | 2009-07-07 | 2011-01-13 | Abbott Laboratories | Biomarkers and methods for detecting alzheimer's disease |
| EP2553466A4 (en) | 2010-04-01 | 2013-10-16 | Banyan Biomarkers Inc | MARKERS AND ASSAYS FOR DETECTING NEUROTOXICITY |
| WO2013086429A2 (en) * | 2011-12-09 | 2013-06-13 | Veracyte, Inc. | Methods and compositions for classification of samples |
| GB2511525A (en) * | 2013-03-05 | 2014-09-10 | Randox Teoranta | Methods and Compositions for the Diagnosis of Alzheimer's Disease |
| GB201310203D0 (en) * | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Materials and methods relating to Alzheimer's disease |
| GB201322094D0 (en) * | 2013-12-13 | 2014-01-29 | Electrophoretics Ltd | Methods and compositions relating to alzheimers disease |
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| JP2018510343A (ja) | 2018-04-12 |
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