CA2964390A1 - Dosage regimen for pegylated interferon - Google Patents

Dosage regimen for pegylated interferon Download PDF

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Publication number
CA2964390A1
CA2964390A1 CA2964390A CA2964390A CA2964390A1 CA 2964390 A1 CA2964390 A1 CA 2964390A1 CA 2964390 A CA2964390 A CA 2964390A CA 2964390 A CA2964390 A CA 2964390A CA 2964390 A1 CA2964390 A1 CA 2964390A1
Authority
CA
Canada
Prior art keywords
interferon
treatment period
subject
weeks
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2964390A
Other languages
English (en)
French (fr)
Inventor
Christoph Klade
Oleh ZAGRIJTSCHUK
Ko-Chung Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PharmaEssentia Corp
Original Assignee
PharmaEssentia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PharmaEssentia Corp filed Critical PharmaEssentia Corp
Publication of CA2964390A1 publication Critical patent/CA2964390A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
CA2964390A 2014-11-06 2015-11-06 Dosage regimen for pegylated interferon Pending CA2964390A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14192114 2014-11-06
EP14192114.8 2014-11-06
PCT/US2015/059410 WO2016073825A1 (en) 2014-11-06 2015-11-06 Dosage regimen for pegylated interferon

Publications (1)

Publication Number Publication Date
CA2964390A1 true CA2964390A1 (en) 2016-05-12

Family

ID=51945707

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2964390A Pending CA2964390A1 (en) 2014-11-06 2015-11-06 Dosage regimen for pegylated interferon

Country Status (32)

Country Link
US (3) US11559567B2 (https=)
EP (2) EP4282485A3 (https=)
JP (2) JP6820841B2 (https=)
KR (2) KR102540109B1 (https=)
CN (1) CN107530403A (https=)
AU (1) AU2015342908B2 (https=)
BR (1) BR112017009193A2 (https=)
CA (1) CA2964390A1 (https=)
CL (1) CL2017001088A1 (https=)
DK (1) DK3215193T3 (https=)
EA (1) EA037151B1 (https=)
ES (1) ES2966888T3 (https=)
FI (1) FI3215193T3 (https=)
HK (1) HK1243627A1 (https=)
HR (1) HRP20231732T1 (https=)
HU (1) HUE064909T2 (https=)
IL (1) IL251627B (https=)
LT (1) LT3215193T (https=)
MX (1) MX389844B (https=)
MY (1) MY191506A (https=)
NZ (1) NZ730924A (https=)
PH (1) PH12017500617B1 (https=)
PL (1) PL3215193T3 (https=)
PT (1) PT3215193T (https=)
RS (1) RS65015B1 (https=)
SG (1) SG11201702798PA (https=)
SI (1) SI3215193T1 (https=)
SM (1) SMT202400028T1 (https=)
TW (1) TWI737583B (https=)
UA (1) UA122867C2 (https=)
WO (1) WO2016073825A1 (https=)
ZA (1) ZA201702704B (https=)

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ES3009748T3 (en) * 2017-01-18 2025-03-31 Inst Nat Sante Rech Med Pharmaceutical compositions for the treatment patients suffering from myeloproliferative disorders
US11414698B2 (en) * 2018-03-22 2022-08-16 Chang Gung Medical Foundation Chang Gung Memorial Hospital At Chiayi Method of quantifying mutant allele burden of target gene
US20230131808A1 (en) * 2020-04-22 2023-04-27 Southlake Pharmaceuticals, Inc. Pegylated interferon tau and compositions and methods thereof
AU2022221496A1 (en) * 2021-08-29 2023-03-16 Pharmaessentia Corporation Method of Using Pegylated Interferon-alpha

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Also Published As

Publication number Publication date
AU2015342908A1 (en) 2017-05-04
KR102724837B1 (ko) 2024-10-31
AU2015342908B2 (en) 2021-06-24
ZA201702704B (en) 2020-10-28
PH12017500617A1 (en) 2017-09-04
NZ730924A (en) 2022-04-29
KR20170083074A (ko) 2017-07-17
JP6820841B2 (ja) 2021-01-27
FI3215193T3 (fi) 2023-12-28
JP2017533192A (ja) 2017-11-09
EP3215193A4 (en) 2018-07-25
SMT202400028T1 (it) 2024-03-13
ES2966888T3 (es) 2024-04-24
TWI737583B (zh) 2021-09-01
CL2017001088A1 (es) 2018-01-12
US20170326206A1 (en) 2017-11-16
EA037151B1 (ru) 2021-02-11
EP3215193B1 (en) 2023-10-04
CN107530403A (zh) 2018-01-02
US20250186552A1 (en) 2025-06-12
IL251627A0 (en) 2017-06-29
US12343381B2 (en) 2025-07-01
SG11201702798PA (en) 2017-05-30
MX389844B (es) 2025-03-04
EP3215193A1 (en) 2017-09-13
IL251627B (en) 2021-12-01
MY191506A (en) 2022-06-28
MX2017005244A (es) 2017-08-18
DK3215193T3 (da) 2024-01-08
PH12017500617B1 (en) 2024-07-03
RS65015B1 (sr) 2024-01-31
LT3215193T (lt) 2024-01-25
JP2021001184A (ja) 2021-01-07
SI3215193T1 (sl) 2024-02-29
HUE064909T2 (hu) 2024-04-28
WO2016073825A1 (en) 2016-05-12
PT3215193T (pt) 2023-12-15
KR102540109B1 (ko) 2023-06-02
UA122867C2 (uk) 2021-01-13
EA201790991A1 (ru) 2017-11-30
EP4282485A2 (en) 2023-11-29
BR112017009193A2 (pt) 2018-01-30
KR20230079520A (ko) 2023-06-07
US20230131552A1 (en) 2023-04-27
US11559567B2 (en) 2023-01-24
TW201618808A (zh) 2016-06-01
PL3215193T3 (pl) 2024-03-18
HK1243627A1 (zh) 2018-07-20
EP4282485A3 (en) 2024-01-17
HRP20231732T1 (hr) 2024-03-15

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