CA2957399C - Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes - Google Patents
Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes Download PDFInfo
- Publication number
- CA2957399C CA2957399C CA2957399A CA2957399A CA2957399C CA 2957399 C CA2957399 C CA 2957399C CA 2957399 A CA2957399 A CA 2957399A CA 2957399 A CA2957399 A CA 2957399A CA 2957399 C CA2957399 C CA 2957399C
- Authority
- CA
- Canada
- Prior art keywords
- paste
- needle
- reservoir
- syringe
- loaded syringe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract description 29
- 238000010254 subcutaneous injection Methods 0.000 title description 6
- 239000007929 subcutaneous injection Substances 0.000 title description 6
- 239000007787 solid Substances 0.000 claims abstract description 67
- 239000012530 fluid Substances 0.000 claims abstract description 41
- 238000007789 sealing Methods 0.000 claims abstract description 12
- 238000004891 communication Methods 0.000 claims abstract description 9
- 238000002347 injection Methods 0.000 claims description 45
- 239000007924 injection Substances 0.000 claims description 45
- 239000000843 powder Substances 0.000 description 33
- 239000000203 mixture Substances 0.000 description 29
- 239000002245 particle Substances 0.000 description 20
- 239000000499 gel Substances 0.000 description 14
- 239000003814 drug Substances 0.000 description 13
- 238000009472 formulation Methods 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- 230000036961 partial effect Effects 0.000 description 10
- 230000001225 therapeutic effect Effects 0.000 description 10
- 239000000126 substance Substances 0.000 description 8
- 229940124597 therapeutic agent Drugs 0.000 description 8
- 239000000047 product Substances 0.000 description 7
- 239000002552 dosage form Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 229920002521 macromolecule Polymers 0.000 description 5
- 239000013618 particulate matter Substances 0.000 description 5
- 239000000546 pharmaceutical excipient Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 238000000418 atomic force spectrum Methods 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 230000009974 thixotropic effect Effects 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 229940090047 auto-injector Drugs 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000006260 foam Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- RMOAERQRBVCTND-RJMJUYIDSA-N CC(OCC(OC(C)=O)COC(C)=O)=O.OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO Chemical compound CC(OCC(OC(C)=O)COC(C)=O)=O.OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO RMOAERQRBVCTND-RJMJUYIDSA-N 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 239000012056 semi-solid material Substances 0.000 description 2
- 239000008299 semisolid dosage form Substances 0.000 description 2
- 239000002356 single layer Substances 0.000 description 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 241000282412 Homo Species 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000005388 borosilicate glass Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000001246 colloidal dispersion Methods 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000000539 dimer Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 235000013773 glyceryl triacetate Nutrition 0.000 description 1
- 239000001087 glyceryl triacetate Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 229940060367 inert ingredients Drugs 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 231100001079 no serious adverse effect Toxicity 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000007962 solid dispersion Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 239000013638 trimer Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31531—Microsyringes, e.g. having piston bore diameter close or equal to needle shaft diameter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/344—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub using additional parts, e.g. clamping rings or collets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M2005/3201—Coaxially assembled needle cannulas placed on top of another, e.g. needles having different diameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462034004P | 2014-08-06 | 2014-08-06 | |
| US62/034,004 | 2014-08-06 | ||
| PCT/US2015/044060 WO2016022831A1 (en) | 2014-08-06 | 2015-08-06 | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2957399A1 CA2957399A1 (en) | 2016-02-11 |
| CA2957399C true CA2957399C (en) | 2023-09-26 |
Family
ID=53836893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2957399A Active CA2957399C (en) | 2014-08-06 | 2015-08-06 | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11129940B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3871709A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6982495B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102428675B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN106573106B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015300944B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2957399C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016022831A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101978527B1 (ko) | 2011-03-10 | 2019-09-03 | 엑스에리스 파머수티클스, 인크. | 펩티드 약물의 비경구 주입을 위한 안정한 제형 |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
| CN106573106B (zh) | 2014-08-06 | 2021-06-22 | Xeris药物公司 | 用于皮内和/或皮下注射糊剂的注射器、试剂盒和方法 |
| US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
| US11752099B2 (en) * | 2017-03-27 | 2023-09-12 | W. L. Gore & Associates, Inc. | Injectable and biodegradable polymer formulations for controlled release of bioactive agents |
| BR112019024987A2 (pt) | 2017-06-02 | 2020-06-16 | Xeris Pharmaceuticals, Inc. | Formulações de fármaco de molécula pequena resistente à precipitação |
| EP3694587A4 (en) * | 2017-10-12 | 2021-08-11 | Leslie, Tufts | PROCESS AND APPARATUS FOR INJECTING A NEUROTOXIN INTO A LOCALIZED ZONE |
| CN111225696B (zh) * | 2017-11-10 | 2023-07-18 | 安进公司 | 用于药物递送装置的柱塞 |
| FR3079421B1 (fr) * | 2018-03-28 | 2024-11-15 | Edix Sa | Presentations injectables, seringues et compositions a liberation prolongee et/ou controlee de lanreotide |
| CN108379697A (zh) * | 2018-05-10 | 2018-08-10 | 山东威高集团医用高分子制品股份有限公司 | 一种皮下注射专用的预灌封注射器 |
| JP2022534873A (ja) * | 2019-05-17 | 2022-08-04 | ウエスト ファーマスーティカル サービシーズ インコーポレイテッド | 治療用液剤のための適応的一次包装 |
| EP3750580B1 (de) * | 2019-06-13 | 2025-12-24 | SCHOTT Pharma Schweiz AG | Mit einem fluid vorfüllbarer oder vorgefüllter behälter sowie kanülenbaugruppe und verschlusssystem für einen mit einem fluid vorfüllbaren oder vorgefüllten behälter |
| MX2024002920A (es) * | 2021-09-09 | 2024-03-27 | Xeris Pharmaceuticals Inc | Formulaciones farmaceuticas inyectables de alta concentracion y metodos de preparacion y uso de las mismas. |
| EP4596003A1 (en) * | 2024-01-30 | 2025-08-06 | Becton Dickinson France | Thin wall cannula |
| WO2025010191A1 (en) * | 2023-07-06 | 2025-01-09 | Becton Dickinson France | Thin wall cannula |
| EP4487890A1 (en) * | 2023-07-06 | 2025-01-08 | Becton Dickinson France | Thin wall cannula |
| CA3237624A1 (en) * | 2023-07-28 | 2025-04-24 | Genentech, Inc. | NEW USES FOR OMALIZUMAB |
Family Cites Families (128)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1929247A (en) * | 1931-01-20 | 1933-10-03 | George N Hein | Syringe equipment and apparatus |
| US3016895A (en) | 1958-08-01 | 1962-01-16 | Pan American Lab Inc | Injector for subcutaneous implantation of solids |
| US5260306A (en) | 1981-07-24 | 1993-11-09 | Fisons Plc | Inhalation pharmaceuticals |
| GB2119248A (en) | 1982-04-28 | 1983-11-16 | John Kenneth Mcmullen | Insulin formulations and method of producing them |
| CH664005A5 (de) | 1984-05-19 | 1988-01-29 | Glatt Maschinen & Apparatebau | Verfahren zum trocknen eines teilchenfoermigen gutes und einrichtung zur durchfuehrung des verfahrens. |
| US5124317A (en) | 1985-08-02 | 1992-06-23 | Farmitalia Carlo Erba S.P.A. | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
| US5977082A (en) | 1985-08-02 | 1999-11-02 | Pharmacia & Upjohn Company | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside |
| US4927571A (en) | 1987-05-18 | 1990-05-22 | Liposome Technology, Inc. | Preparation of injectable doxorubicin/liposome suspension |
| US4848094A (en) | 1988-04-29 | 1989-07-18 | Union Carbide Corporation | Droplet freezing method and apparatus |
| US5031336A (en) | 1989-08-31 | 1991-07-16 | Abbott Laboratories | Lyophilization of bulk pharmaceuticals |
| US5092843A (en) | 1990-04-12 | 1992-03-03 | Survival Technology, Inc. | Dispersion multichamber auto-injector |
| CA2081474A1 (en) | 1990-05-08 | 1991-11-09 | Manzer Durrani | Direct spray-dried drug/lipid powder composition |
| AU7880991A (en) | 1990-05-10 | 1991-11-27 | Novo Nordisk A/S | A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols |
| US5208998A (en) | 1991-02-25 | 1993-05-11 | Oyler Jr James R | Liquid substances freeze-drying systems and methods |
| JP3277342B2 (ja) | 1992-09-02 | 2002-04-22 | 武田薬品工業株式会社 | 徐放性マイクロカプセルの製造法 |
| ATE164315T1 (de) * | 1992-12-15 | 1998-04-15 | Sanofi Sa | Vorrichtung zur vorbereitung einer lösung, einer suspension oder einer emulsion einer medizinischen lösung |
| KR950005701U (ko) * | 1993-08-16 | 1995-03-20 | 한상욱 | 용기 플런저에 의한 두가지 약물연속 주입 주사기 |
| US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| US5652216A (en) | 1994-05-26 | 1997-07-29 | Novo Nordisk A/S | Pharmaceutical preparation |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| US5595760A (en) | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| MX9702357A (es) | 1994-09-29 | 1997-06-28 | Andaris Ltd | Microparticulas secadas por aspersion como vehiculos terapeuticos. |
| US5932547A (en) | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
| US5945128A (en) | 1996-09-04 | 1999-08-31 | Romano Deghenghi | Process to manufacture implants containing bioactive peptides |
| IN184589B (cg-RX-API-DMAC7.html) | 1996-10-16 | 2000-09-09 | Alza Corp | |
| IL130532A0 (en) | 1996-12-20 | 2000-06-01 | Alza Corp | Gel composition and methods |
| AU5806898A (en) | 1996-12-31 | 1998-07-31 | Inhale Therapeutic Systems | Processes and compositions for spray drying hydrophobic drugs in organic solventsuspensions of hydrophilic excipients |
| EP1285667B1 (en) | 1997-11-18 | 2006-06-14 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Pharmaceutical injectable solution of paracetamol and combinations of paracetamol with other active substances |
| FR2783433B1 (fr) * | 1998-09-18 | 2001-02-16 | Delab | Seringues pour l'administration de formulations pateuses ou semi-solides |
| SE9803662D0 (sv) | 1998-10-26 | 1998-10-26 | Pharmacia & Upjohn Ab | Autoinjector |
| US6199297B1 (en) | 1999-02-01 | 2001-03-13 | Integrated Biosystems, Inc. | Lyophilization apparatus and methods |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| US6253463B1 (en) | 1999-04-26 | 2001-07-03 | Niro A/S | Method of spray drying |
| US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| US7582311B1 (en) | 1999-10-15 | 2009-09-01 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| US7651703B2 (en) | 1999-10-15 | 2010-01-26 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| US6478776B1 (en) | 2000-04-05 | 2002-11-12 | Biocardia, Inc. | Implant delivery catheter system and methods for its use |
| US20030026844A1 (en) | 2000-04-18 | 2003-02-06 | Hee-Yong Lee | Injectable sustained release pharmaceutical composition and processes for preparing the same |
| US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
| WO2002000137A1 (en) | 2000-06-28 | 2002-01-03 | Shukla Atul J | Biodegradable vehicles and delivery systems of biologically active substances |
| CA2419067C (en) | 2000-08-18 | 2008-12-23 | Takeda Chemical Industries, Ltd. | Injectable composition comprising benzimidazole compound and strong alkali |
| RO120121B1 (ro) | 2000-12-18 | 2005-09-30 | Elena Ionaşcu | Soluţie injectabilă, cu efect antiinflamator, procedeu de obţinere şi metodă de tratament a bolilor autoimune |
| US8166969B2 (en) | 2001-03-06 | 2012-05-01 | Texas Research International, Inc. | Chemically and biologically resistant hydration system |
| US6676958B2 (en) | 2001-06-19 | 2004-01-13 | Advanced Bioadjuvants, Llc | Adjuvant composition for mucosal and injection delivered vaccines |
| JP4490095B2 (ja) | 2001-06-29 | 2010-06-23 | メドグラフト マイクロテック インコーポレイテッド | 生体分解性の注入可能な移植物およびそれに関連する製造方法ならびに使用方法 |
| CA2448814A1 (en) | 2001-07-09 | 2003-01-23 | Yamanouchi Pharmaceutical Co., Ltd. | Composition for sustained release injections and production method thereof |
| US6733813B2 (en) | 2001-08-02 | 2004-05-11 | Ocean Spray Cranberries, Inc. | Process for producing acids-enriched juice and acids-reduced juice |
| CN1703197A (zh) | 2001-11-14 | 2005-11-30 | 阿尔扎有限公司 | 可注射的长效组合物和其使用 |
| DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| HRPK20040615B3 (en) | 2001-12-18 | 2005-10-31 | Uni-Pharma Kleon Tsetis Pharmaceutical LaboratorieIoulia Tseti | Parenteral composition of paracetamol |
| CN1171610C (zh) | 2002-04-23 | 2004-10-20 | 张瑞香 | 一种治疗心脑血管和眼底病的中药针剂及其制备方法 |
| US8871241B2 (en) | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
| ATE433458T1 (de) | 2002-10-17 | 2009-06-15 | Univ British Columbia | Modulatoren von ship-1 |
| RU2340334C2 (ru) | 2002-10-25 | 2008-12-10 | Домпе С.П.А. | Безболезненные инъецируемые композиции, содержащие соли 2-арилпропионовых кислот |
| CN1750839B (zh) | 2002-12-18 | 2013-11-13 | 瓦利奈科斯公司 | 类辣椒素的给药 |
| CN1507858A (zh) | 2002-12-19 | 2004-06-30 | 王玉万 | 含氟化氯霉素的兽用液体制剂 |
| AU2014200476C1 (en) * | 2002-12-20 | 2015-12-03 | Xeris Pharmaceuticals, Inc. | Intracutaneous injection |
| EP3597262B1 (en) * | 2002-12-20 | 2023-12-27 | Xeris Pharmaceuticals, Inc. | Formulation for intracutaneous injection |
| PL1468697T3 (pl) | 2003-04-14 | 2008-05-30 | Wyeth Corp | Kompozycje zawierające piperacyklinę i tazobaktam przydatne do wstrzykiwań |
| WO2004098643A1 (en) | 2003-04-14 | 2004-11-18 | Wyeth Holdings Corporation | Compositions containing piperacillin and tazobactam useful for injection |
| KR100517643B1 (ko) | 2003-07-25 | 2005-09-28 | 한국과학기술연구원 | 온도 감응성 폴리포스파젠계 고분자, 이의 제조방법 및이를 이용한 주입형 온도 감응성 폴리포스파젠 하이드로젤 |
| US20050100538A1 (en) | 2003-07-31 | 2005-05-12 | Attawia Mohamed | Intradiscal injection of anti-oxidants |
| SI1502589T1 (sl) | 2003-07-31 | 2006-12-31 | Emdoka Bvba Drug Registration | Veterinarske vodne injektibilne suspenzije, ki vsebujejo florfenikol |
| DE602004013447T2 (de) | 2003-08-22 | 2009-06-25 | Singulus Technologies Ag | Verfahren zum verkleben von scheibenförmigen substraten und vorrichtung zur durchführung des verfahrens |
| CN1856296A (zh) | 2003-09-30 | 2006-11-01 | 阿库斯菲尔公司 | 可注射的、口服、或局部用缓释药物制剂 |
| US20080248999A1 (en) | 2007-04-04 | 2008-10-09 | Biodel Inc. | Amylin formulations |
| WO2005094891A2 (en) | 2004-03-12 | 2005-10-13 | Intercell Ag | Method for solubilising peptide mixtures |
| US20050240166A1 (en) * | 2004-04-26 | 2005-10-27 | Microsolutions, Inc. | Implantable device, formulation and method for anti-psychotic therapy using risperidone |
| MXPA06012992A (es) * | 2004-05-12 | 2007-02-12 | Baxter Int | Microesferas que comprenden proteina y que muestran inyectabilidad en altas concentraciones de este agente. |
| US20060160823A1 (en) | 2004-05-28 | 2006-07-20 | Leonore Witchey-Lakshmanan | Particulate-stabilized injectable pharmaceutical compositions of Posaconazole |
| US20080220069A1 (en) | 2004-09-13 | 2008-09-11 | Pr Pharmaceuticals, Inc. | Long Acting Injectable Crystal Formulations of Estradiol Metabolites and Methods of Using Same |
| CA2595606C (en) | 2005-01-27 | 2014-12-16 | Erimos Pharmaceuticals Llc | Oral formulations for delivery of catecholic butanes including ndga compounds |
| US20060246033A1 (en) * | 2005-03-02 | 2006-11-02 | Cook Biotech Incorporated | Injectable bulking agent compositions |
| AU2006235183B2 (en) | 2005-04-08 | 2011-02-10 | Amylin Pharmaceuticals, Llc | Pharmaceutical formulations comprising incretin peptide and aprotic polar solvent |
| US20080305161A1 (en) | 2005-04-13 | 2008-12-11 | Pfizer Inc | Injectable depot formulations and methods for providing sustained release of nanoparticle compositions |
| JP5199079B2 (ja) | 2005-06-17 | 2013-05-15 | リガンド・ファーマシューティカルズ・インコーポレイテッド | アンドロゲン受容体モジュレーター化合物および方法 |
| US8435224B2 (en) | 2005-09-12 | 2013-05-07 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds |
| RU2427383C2 (ru) | 2006-01-18 | 2011-08-27 | КьюПиЭс, ЭлЭлСи | Фармацевтические композиции с повышенной стабильностью |
| AR054215A1 (es) | 2006-01-20 | 2007-06-13 | Eriochem Sa | Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit |
| US9295790B2 (en) * | 2006-05-05 | 2016-03-29 | Retractable Technologies, Inc. | Syringe with recessed nose and protective guard for use with frontal attachments |
| JPWO2007132732A1 (ja) | 2006-05-17 | 2009-09-24 | テルモ株式会社 | 留置針組立体 |
| EP2021094A4 (en) | 2006-05-25 | 2010-02-10 | Gen Hospital Corp | ANTIBODY NETWORK AND METHOD FOR INHIBITING THE NETWORKING OF INJECTABLE HYDROGEL FORMULATIONS |
| NZ575435A (en) | 2006-09-07 | 2012-01-12 | Merial Ltd | Soft chewable, tablet, and long-acting injectable veterinary antibiotic formulations |
| KR20090087441A (ko) | 2006-10-05 | 2009-08-17 | 파나세아 바이오테크 리미티드 | 새로운 형태의 주입형 데포 조성물 및 이를 위한 조제방법 |
| WO2008098212A2 (en) | 2007-02-08 | 2008-08-14 | Diobex, Inc. | Extended release formulations of glucagon and other peptides and proteins |
| PL2157967T3 (pl) | 2007-04-23 | 2013-06-28 | Intarcia Therapeutics Inc | Formulacje zawiesinowe peptydów insulinotropowych i ich zastosowania |
| US20100120660A1 (en) | 2007-04-30 | 2010-05-13 | Per Balschmidt | Highly concentrated insulin solutions and compositions |
| WO2008132224A2 (en) | 2007-04-30 | 2008-11-06 | Novo Nordisk A/S | Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein |
| JP2009011341A (ja) * | 2007-06-29 | 2009-01-22 | Yuka Denshi Co Ltd | ペースト状材料充填容器 |
| US8946208B2 (en) | 2007-08-31 | 2015-02-03 | Archimedes Development Limited | Non-aqueous pharmaceutical composition |
| US20090088393A1 (en) | 2007-09-28 | 2009-04-02 | Zomanex, Llc | Methods and formulations for converting intravenous and injectable drugs into oral dosage forms |
| WO2009060473A2 (en) | 2007-11-06 | 2009-05-14 | Panacea Biotec Limited | Injectable compositions, processes and uses thereof |
| EP2060268A1 (en) | 2007-11-15 | 2009-05-20 | Novo Nordisk A/S | Pharmaceutical compositions for pulmonary or nasal delivery of peptides |
| US20090149541A1 (en) | 2007-11-28 | 2009-06-11 | Yafit Stark | Method of delaying the onset of clinically definite multiple sclerosis |
| EP2222636B1 (en) | 2007-12-21 | 2013-04-10 | Ligand Pharmaceuticals Inc. | Selective androgen receptor modulators (sarms) and uses thereof |
| RU2537139C2 (ru) | 2008-01-15 | 2014-12-27 | Эбботт Гмбх Унд Ко.Кг | Порошковые белковые композиции и способы их получения |
| KR101517415B1 (ko) | 2008-05-14 | 2015-05-07 | 에스케이바이오팜 주식회사 | 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물 |
| CN102105134B (zh) | 2008-07-23 | 2013-08-14 | 印度血清及疫苗有限公司 | 稳定的可注射的水包油型多烯紫杉醇纳米乳剂 |
| GB0815435D0 (en) | 2008-08-22 | 2008-10-01 | Camurus Ab | Formulations |
| WO2010024209A1 (ja) | 2008-08-25 | 2010-03-04 | 電気化学工業株式会社 | 注射器 |
| JP5670335B2 (ja) | 2008-09-25 | 2015-02-18 | セファロン、インク． | ベンダムスチン液体製剤 |
| DK2384210T3 (da) * | 2008-12-02 | 2017-11-27 | Allergan Inc | Injektionsanordning |
| US20110118578A1 (en) | 2009-11-17 | 2011-05-19 | Roche Diagnostics Operations, Inc. | Hypoglycemic treatment methods and systems |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| AU2011259691B2 (en) * | 2010-05-28 | 2014-02-20 | Kuraray Noritake Dental Inc. | Cartridge-type dispenser |
| GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| WO2012012460A1 (en) * | 2010-07-19 | 2012-01-26 | Xeris Pharmaceuticals, Inc. | Stable glucagon formulations for the treatment of hypoglycemia |
| JP5632226B2 (ja) | 2010-07-30 | 2014-11-26 | 株式会社細川洋行 | 医療用多層チューブ、および医療用輸液バッグ |
| US8404268B2 (en) * | 2010-10-26 | 2013-03-26 | Kyphon Sarl | Locally targeted anti-fibrotic agents and methods of use |
| KR101978527B1 (ko) | 2011-03-10 | 2019-09-03 | 엑스에리스 파머수티클스, 인크. | 펩티드 약물의 비경구 주입을 위한 안정한 제형 |
| CN102430175A (zh) * | 2011-09-01 | 2012-05-02 | 严慈 | 注射器 |
| US9138479B2 (en) | 2011-10-31 | 2015-09-22 | Xeris Pharmaceuticals, Inc. | Formulations for the treatment of diabetes |
| SG10201709555SA (en) | 2012-05-18 | 2017-12-28 | Genentech Inc | High-concentration monoclonal antibody formulations |
| US9522235B2 (en) | 2012-05-22 | 2016-12-20 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
| US20130338792A1 (en) * | 2012-06-15 | 2013-12-19 | Arthrex, Inc. | Implantation of micronized allograft tissue over a microfractured defect |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
| CA2882958A1 (en) | 2012-08-29 | 2014-03-06 | Mannkind Corporation | Method and composition for treating hyperglycemia |
| US9226797B2 (en) * | 2012-11-04 | 2016-01-05 | Miba Medical Inc. | Computer aided implantation of body implants |
| CN202982798U (zh) * | 2012-11-08 | 2013-06-12 | 苏州市雅思精密模具有限公司 | 一种一次性注射器 |
| US9018162B2 (en) | 2013-02-06 | 2015-04-28 | Xeris Pharmaceuticals, Inc. | Methods for rapidly treating severe hypoglycemia |
| JP2016518391A (ja) * | 2013-05-01 | 2016-06-23 | ハルシオン，インコーポレイテッド | 急性皮膚創傷の治療に適したヒドロゲル |
| US9668826B2 (en) * | 2013-11-06 | 2017-06-06 | 3M Innovative Properties Company | Handheld viscous dental paste dispenser |
| CN203677662U (zh) * | 2013-11-18 | 2014-07-02 | 苏州林华医疗器械有限公司 | 一种预充式注射器 |
| CN106132430A (zh) | 2014-02-06 | 2016-11-16 | Xeris药物公司 | 稳定肽制剂及其制备方法 |
| WO2015153728A1 (en) | 2014-04-02 | 2015-10-08 | Xeris Pharmaceuticals, Inc. | Polar aprotic solvent-compatible infusion sets, components, and methods |
| CN106573106B (zh) | 2014-08-06 | 2021-06-22 | Xeris药物公司 | 用于皮内和/或皮下注射糊剂的注射器、试剂盒和方法 |
| WO2016196976A1 (en) | 2015-06-04 | 2016-12-08 | Xeris Pharmaceuticals, Inc. | Glucagon delivery apparatuses and related methods |
| WO2016201248A1 (en) | 2015-06-10 | 2016-12-15 | Xeris Pharmaceuticals, Inc. | Use of low dose glucagon |
-
2015
- 2015-08-06 CN CN201580042185.5A patent/CN106573106B/zh active Active
- 2015-08-06 US US15/501,333 patent/US11129940B2/en active Active
- 2015-08-06 JP JP2017506262A patent/JP6982495B2/ja active Active
- 2015-08-06 KR KR1020177006166A patent/KR102428675B1/ko active Active
- 2015-08-06 AU AU2015300944A patent/AU2015300944B2/en active Active
- 2015-08-06 EP EP21156886.0A patent/EP3871709A1/en active Pending
- 2015-08-06 CA CA2957399A patent/CA2957399C/en active Active
- 2015-08-06 WO PCT/US2015/044060 patent/WO2016022831A1/en not_active Ceased
- 2015-08-06 EP EP15750582.7A patent/EP3185932A1/en not_active Ceased
-
2020
- 2020-10-15 JP JP2020173883A patent/JP2021010767A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR102428675B1 (ko) | 2022-08-02 |
| AU2015300944B2 (en) | 2019-07-11 |
| CN106573106A (zh) | 2017-04-19 |
| JP2021010767A (ja) | 2021-02-04 |
| US20170216529A1 (en) | 2017-08-03 |
| CN106573106B (zh) | 2021-06-22 |
| EP3185932A1 (en) | 2017-07-05 |
| EP3871709A1 (en) | 2021-09-01 |
| CA2957399A1 (en) | 2016-02-11 |
| AU2015300944A1 (en) | 2017-03-02 |
| KR20170040330A (ko) | 2017-04-12 |
| JP2017522983A (ja) | 2017-08-17 |
| WO2016022831A1 (en) | 2016-02-11 |
| JP6982495B2 (ja) | 2021-12-17 |
| US11129940B2 (en) | 2021-09-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2957399C (en) | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes | |
| EP2432528B1 (en) | Steroid delivery system | |
| WO2014169081A3 (en) | Methods and devices for point of use mixing of pharmaceutical formulations | |
| CN104507519A (zh) | 医用注射装置 | |
| CN103816111A (zh) | 一种罗哌卡因纳米脂质载体温敏原位凝胶及其制备方法 | |
| AU2015364280A1 (en) | Method and compositions for dissolving or solubilizing therapeutic agents | |
| US20250144313A1 (en) | Methods and devices for fracturing a hydrogel prior to delivery through a needle | |
| JP2021510314A (ja) | 低圧注入での高流量システムおよびその針セット | |
| TW201630591A (zh) | 醫藥用乳化製劑及其製造方法 | |
| HK1236856B (zh) | 用於皮内和/或皮下注射糊剂的注射器、试剂盒和方法 | |
| HK1236856A1 (en) | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes | |
| CN118103030A (zh) | 可注射的高浓度药物制剂及其制造和使用方法 | |
| US20230085357A1 (en) | Injectable high concentration pharmaceutical formulations and methods of manufacturing and use thereof | |
| Sahu et al. | An Overview on Recent Advances in Pharmaceutical Suspensions | |
| CN102389571B (zh) | 一种可体内注射的药物缓释栓剂 | |
| AU2014200476A1 (en) | Intracutaneous injection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |
|
| EEER | Examination request |
Effective date: 20200804 |