CA2957258C - Immunological reagents - Google Patents
Immunological reagents Download PDFInfo
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- CA2957258C CA2957258C CA2957258A CA2957258A CA2957258C CA 2957258 C CA2957258 C CA 2957258C CA 2957258 A CA2957258 A CA 2957258A CA 2957258 A CA2957258 A CA 2957258A CA 2957258 C CA2957258 C CA 2957258C
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| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| CN105339389B (zh) | 2013-05-02 | 2021-04-27 | 安奈普泰斯生物有限公司 | 针对程序性死亡-1(pd-1)的抗体 |
| TWI693232B (zh) | 2014-06-26 | 2020-05-11 | 美商宏觀基因股份有限公司 | 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法 |
| EP3177644B1 (en) * | 2014-08-05 | 2020-10-07 | Mabquest SA | Immunological reagents binding to pd-1 |
| US9982052B2 (en) * | 2014-08-05 | 2018-05-29 | MabQuest, SA | Immunological reagents |
| BR112017011092A2 (pt) | 2014-11-26 | 2017-12-26 | Xencor Inc | anticorpos heterodiméricos que ligam cd3 e antígenos de tumor |
| DK3303394T3 (da) | 2015-05-29 | 2020-07-06 | Agenus Inc | Anti-ctla-4-antistoffer og fremgangsmåder til anvendelse deraf |
| TWI773646B (zh) | 2015-06-08 | 2022-08-11 | 美商宏觀基因股份有限公司 | 結合lag-3的分子和其使用方法 |
| CN108368170B (zh) | 2015-07-13 | 2022-04-15 | 西托姆克斯治疗公司 | 抗pd-1抗体、可活化抗pd-1抗体及其使用方法 |
| WO2017019846A1 (en) | 2015-07-30 | 2017-02-02 | Macrogenics, Inc. | Pd-1-binding molecules and methods use thereof |
| EA201890790A1 (ru) | 2015-09-29 | 2018-10-31 | Селджин Корпорейшн | Связывающие pd-1 белки и способы их применения |
| HUE057837T2 (hu) | 2015-11-03 | 2022-06-28 | Janssen Biotech Inc | PD-1-et specifikusan kötõ ellenanyagok és alkalmazásaik |
| CR20180318A (es) | 2015-12-14 | 2018-09-19 | Macrogenics Inc | Moléculas biespecíficas que tienen inmunorreactividad con pd-1 y ctla-4, y métodos de uso de las mismas |
| US11214617B2 (en) * | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| EP3405497A2 (en) | 2016-01-22 | 2018-11-28 | Mabquest SA | Immunological reagents |
| CN106008714B (zh) * | 2016-05-24 | 2019-03-15 | 瑞阳(苏州)生物科技有限公司 | 抗人pd-1人源化单克隆抗体及其应用 |
| MY195089A (en) | 2016-05-27 | 2023-01-10 | Agenus Inc | Anti-Tim-3 Antibodies and Methods of use thereof |
| EP3468586B1 (en) * | 2016-06-14 | 2024-08-07 | Xencor, Inc. | Bispecific checkpoint inhibitor antibodies |
| JP2019531284A (ja) | 2016-09-19 | 2019-10-31 | セルジーン コーポレイション | Ｐｄ−１結合タンパク質を使用して免疫障害を治療する方法 |
| WO2018053401A1 (en) | 2016-09-19 | 2018-03-22 | Celgene Corporation | Methods of treating vitiligo using pd-1 binding proteins |
| IL265800B2 (en) | 2016-10-11 | 2023-10-01 | Agenus Inc | Anti-LAG-3 antibodies and methods of using them |
| WO2018085468A1 (en) | 2016-11-01 | 2018-05-11 | Anaptysbio, Inc. | Antibodies directed against programmed death- 1 (pd-1) |
| JP7086066B2 (ja) * | 2016-11-02 | 2022-06-17 | ジョンス セラピューティクス， インコーポレイテッド | Ｐｄ－１に対する抗体及びその使用 |
| WO2018106864A1 (en) | 2016-12-07 | 2018-06-14 | Agenus Inc. | Antibodies and methods of use thereof |
| PT3551660T (pt) | 2016-12-07 | 2023-11-30 | Ludwig Inst For Cancer Res Ltd | Anticorpos anti-ctla-4 e métodos de uso dos mesmos |
| EP3565841A1 (en) * | 2017-01-06 | 2019-11-13 | Crescendo Biologics Limited | Single domain antibodies to programmed cell death (pd-1) |
| FI3565844T3 (fi) | 2017-01-09 | 2023-05-09 | Tesaro Inc | Menetelmiä syövän hoitamiseksi anti-pd-1 -vasta-aineilla |
| AU2018207172B2 (en) | 2017-01-13 | 2023-10-12 | Mink Therapeutics, Inc. | T cell receptors that bind to NY-ESO-1 and methods of use thereof |
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| AU2018234810B2 (en) | 2017-03-15 | 2023-05-11 | Pandion Operations, Inc. | Targeted immunotolerance |
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| CN106939049B (zh) * | 2017-04-20 | 2019-10-01 | 苏州思坦维生物技术股份有限公司 | 拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用 |
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| US11214617B2 (en) * | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| EP3405497A2 (en) * | 2016-01-22 | 2018-11-28 | Mabquest SA | Immunological reagents |
-
2015
- 2015-08-05 EP EP15750136.2A patent/EP3177644B1/en active Active
- 2015-08-05 US US15/329,760 patent/US9982053B2/en active Active
- 2015-08-05 CA CA2957258A patent/CA2957258C/en active Active
- 2015-08-05 WO PCT/IB2015/055943 patent/WO2016020856A2/en not_active Ceased
- 2015-08-05 ES ES15750136T patent/ES2847311T3/es active Active
- 2015-08-05 PT PT157501362T patent/PT3177644T/pt unknown
- 2015-08-05 DK DK15750136.2T patent/DK3177644T3/da active
- 2015-08-05 CN CN201580042199.7A patent/CN107074947B/zh active Active
- 2015-08-05 AU AU2015298356A patent/AU2015298356B2/en active Active
- 2015-08-05 JP JP2017526774A patent/JP6629321B2/ja active Active
- 2015-08-05 PL PL15750136T patent/PL3177644T3/pl unknown
- 2015-08-05 SG SG11201700672YA patent/SG11201700672YA/en unknown
- 2015-08-05 KR KR1020177004575A patent/KR102357893B1/ko active Active
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2018
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2021
- 2021-09-27 US US17/485,752 patent/US20220169733A1/en not_active Abandoned
Also Published As
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|---|---|
| AU2015298356A1 (en) | 2017-02-16 |
| SG11201700672YA (en) | 2017-02-27 |
| US20190106493A1 (en) | 2019-04-11 |
| EP3177644B1 (en) | 2020-10-07 |
| US20170226210A1 (en) | 2017-08-10 |
| CN107074947A (zh) | 2017-08-18 |
| US20220169733A1 (en) | 2022-06-02 |
| US11130807B2 (en) | 2021-09-28 |
| PT3177644T (pt) | 2021-01-13 |
| JP6629321B2 (ja) | 2020-01-15 |
| JP2017531028A (ja) | 2017-10-19 |
| KR102357893B1 (ko) | 2022-02-04 |
| ES2847311T3 (es) | 2021-08-02 |
| US9982053B2 (en) | 2018-05-29 |
| AU2015298356B2 (en) | 2020-11-19 |
| KR20170069996A (ko) | 2017-06-21 |
| CA2957258A1 (en) | 2016-02-11 |
| WO2016020856A2 (en) | 2016-02-11 |
| WO2016020856A3 (en) | 2016-03-31 |
| DK3177644T3 (da) | 2021-01-11 |
| PL3177644T3 (pl) | 2021-06-14 |
| CN107074947B (zh) | 2021-04-09 |
| EP3177644A2 (en) | 2017-06-14 |
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