CA2956646A1 - Methods and compositions for diagnosing, prognosing, and confirming preeclampsia - Google Patents

Methods and compositions for diagnosing, prognosing, and confirming preeclampsia Download PDF

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Publication number
CA2956646A1
CA2956646A1 CA2956646A CA2956646A CA2956646A1 CA 2956646 A1 CA2956646 A1 CA 2956646A1 CA 2956646 A CA2956646 A CA 2956646A CA 2956646 A CA2956646 A CA 2956646A CA 2956646 A1 CA2956646 A1 CA 2956646A1
Authority
CA
Canada
Prior art keywords
biomarkers
preeclampsia
levels
p1gf
sflt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2956646A
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English (en)
French (fr)
Inventor
Matthew Cooper
Lyndal HESTERBERG
Eric KUNKEL
Evangelos Hytopoulos
Kimberly SCHWARTZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2956646A1 publication Critical patent/CA2956646A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/515—Angiogenesic factors; Angiogenin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2956646A 2014-07-30 2015-07-30 Methods and compositions for diagnosing, prognosing, and confirming preeclampsia Abandoned CA2956646A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462031132P 2014-07-30 2014-07-30
US62/031,132 2014-07-30
US201462031834P 2014-07-31 2014-07-31
US62/031,834 2014-07-31
US201562115077P 2015-02-11 2015-02-11
US62/115,077 2015-02-11
PCT/US2015/042976 WO2016019176A1 (en) 2014-07-30 2015-07-30 Methods and compositions for diagnosing, prognosing, and confirming preeclampsia

Publications (1)

Publication Number Publication Date
CA2956646A1 true CA2956646A1 (en) 2016-02-04

Family

ID=55218328

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2956646A Abandoned CA2956646A1 (en) 2014-07-30 2015-07-30 Methods and compositions for diagnosing, prognosing, and confirming preeclampsia

Country Status (5)

Country Link
EP (1) EP3175239A1 (zh)
CN (1) CN107155350A (zh)
CA (1) CA2956646A1 (zh)
MA (1) MA40325A (zh)
WO (1) WO2016019176A1 (zh)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112018015532A2 (pt) * 2016-02-29 2018-12-26 Hoffmann La Roche métodos para o diagnóstico de pré-eclâmpsia, para avaliar a gravidade da pré-eclâmpsia, e para o monitoramento pré-eclâmpsia, usos de biomarcador, kit adaptado para a realização do método e dispositivo adaptado para diagnosticar se uma paciente sofre de pré-eclâmpsia
FR3057070B1 (fr) * 2016-10-04 2018-11-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Diagnostique et pronostique precoce de la preeclampsie
CN107312846A (zh) * 2017-07-12 2017-11-03 北京赛尔维康生物医学科技有限公司 Capg和ptgis基因在制备脊柱侧弯检测试剂盒中的应用
EP3682250A4 (en) 2017-09-13 2021-03-03 Progenity, Inc. PRECLAMPSY BIOMARKERS AND RELATED SYSTEMS AND PROCEDURES
EP3701043B1 (en) * 2017-10-23 2023-11-22 CZ Biohub SF, LLC A noninvasive molecular clock for fetal development predicts gestational age and preterm delivery
AU2019218548A1 (en) * 2018-02-09 2020-09-03 Metabolomic Diagnostics Limited Methods of predicting pre term birth from preeclampsia using metabolic and protein biomarkers
CN108717123A (zh) * 2018-04-25 2018-10-30 卢英 一种联合检测sFlt-1/PLGF和HLA-G检测先兆子痫的方法
CN112673259A (zh) * 2018-07-20 2021-04-16 豪夫迈·罗氏有限公司 基于igfbp-7的先兆子痫预测
KR20200049365A (ko) * 2018-10-31 2020-05-08 서울대학교산학협력단 임신성 당뇨 및 임신 중 고혈압 예측을 위한 바이오마커
CN109554479A (zh) * 2019-01-21 2019-04-02 中南大学 Pigc基因在制备肝癌辅助诊断及预后判断制剂上的应用
CN109919054B (zh) * 2019-02-25 2023-04-07 电子科技大学 一种基于机器视觉的试剂卡自动分类的检测方法
CN110596386B (zh) * 2019-09-20 2020-06-02 四川大学华西医院 Egflam自身抗体检测试剂在制备肺癌筛查试剂盒中的用途
CN112710836A (zh) * 2019-10-25 2021-04-27 成都敬守务成医疗科技有限责任公司 人类白细胞抗原g标志物的用途及试剂盒
EP4070113A4 (en) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS
CN112180098B (zh) * 2019-12-06 2023-02-17 中山大学 胎盘相关疾病标志物的筛选方法及标志物
CN111257445B (zh) * 2020-01-22 2022-09-09 上海交通大学医学院附属仁济医院 用于sle孕妇病情监测及其胎儿结局预测的产品及方法
CN112305220B (zh) * 2020-06-03 2021-07-23 四川大学华西第二医院 组织蛋白酶z在子痫前期的早期预警、诊断中的应用和产品
KR102233909B1 (ko) * 2020-07-13 2021-03-30 서울대학교산학협력단 임신성 당뇨 및 임신 중 고혈압 예측을 위한 바이오마커
CN111951969A (zh) * 2020-08-05 2020-11-17 中翰盛泰生物技术股份有限公司 Hbp在高危妊娠预测中的应用
GB202012830D0 (en) * 2020-08-17 2020-09-30 Univ Tartu Method of prognosing preeclampsia
CN112175963A (zh) * 2020-09-30 2021-01-05 安徽省天长市周氏羊业有限公司 一种spp1基因及评估绵羊单卵泡中高尔基体发育质量的方法
CN112535886B (zh) * 2020-11-12 2022-07-12 杭州苏铂科技有限公司 去除金纳米棒溶液中的ctab的方法
CN112946299B (zh) * 2021-01-29 2022-11-29 暨南大学 定量ftl的产品在制备子痫前期诊断工具中的应用
CN112946283B (zh) * 2021-01-29 2022-11-29 暨南大学 定量a2m的产品在制备子痫前期诊断工具中的应用
CN113092777B (zh) * 2021-03-26 2023-11-14 泰达国际心血管病医院 孕早期进行重症子痫前期患者筛查的方法
WO2023087004A2 (en) * 2021-11-11 2023-05-19 Nx Prenatal Inc. Methods of preparing and analyzing samples for biomarkers associated with placenta accreta
CN117867094A (zh) * 2022-10-10 2024-04-12 天津云检医疗器械有限公司 用于先兆子痫风险预测、评估或诊断的生物标志物、试剂盒及方法
CN117647653B (zh) * 2023-12-22 2024-05-07 广州医科大学附属第三医院（广州重症孕产妇救治中心、广州柔济医院） 一种与子痫前期相关的生物标志物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE519109T1 (de) * 2004-12-21 2011-08-15 Univ Yale Präeklampsie-diagnose
WO2009097584A1 (en) * 2008-01-30 2009-08-06 Proteogenix, Inc. Maternal serum biomarkers for detection of pre-eclampsia
EP2847354A4 (en) * 2012-05-08 2015-12-30 Univ Leland Stanford Junior METHODS AND COMPOSITIONS FOR PERFORMING A PRECLAMPSY ASSESSMENT
WO2014036440A2 (en) * 2012-08-30 2014-03-06 Ansh Labs Llc Papp-a2 as a marker for monitoring, predicting and diagnosing preeclampsia

Also Published As

Publication number Publication date
MA40325A (fr) 2016-02-04
CN107155350A (zh) 2017-09-12
EP3175239A1 (en) 2017-06-07
WO2016019176A1 (en) 2016-02-04

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Date Code Title Description
FZDE Discontinued

Effective date: 20190730