ATE519109T1 - Präeklampsie-diagnose - Google Patents
Präeklampsie-diagnoseInfo
- Publication number
- ATE519109T1 ATE519109T1 AT05857213T AT05857213T ATE519109T1 AT E519109 T1 ATE519109 T1 AT E519109T1 AT 05857213 T AT05857213 T AT 05857213T AT 05857213 T AT05857213 T AT 05857213T AT E519109 T1 ATE519109 T1 AT E519109T1
- Authority
- AT
- Austria
- Prior art keywords
- pregnancy
- preeclampsia
- risk
- levels
- present
- Prior art date
Links
- 201000011461 pre-eclampsia Diseases 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title 1
- 230000035935 pregnancy Effects 0.000 abstract 2
- 206010061452 Complication of pregnancy Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 108010082093 Placenta Growth Factor Proteins 0.000 abstract 1
- 102100035194 Placenta growth factor Human genes 0.000 abstract 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 abstract 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 abstract 1
- 239000002870 angiogenesis inducing agent Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63794804P | 2004-12-21 | 2004-12-21 | |
| PCT/US2005/047010 WO2006069373A2 (en) | 2004-12-21 | 2005-12-21 | Diagnosis of preeclampsia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE519109T1 true ATE519109T1 (de) | 2011-08-15 |
Family
ID=36602368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05857213T ATE519109T1 (de) | 2004-12-21 | 2005-12-21 | Präeklampsie-diagnose |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7727733B2 (de) |
| EP (2) | EP1839056B1 (de) |
| JP (1) | JP5009811B2 (de) |
| CN (1) | CN101163970A (de) |
| AT (1) | ATE519109T1 (de) |
| ES (2) | ES2475975T3 (de) |
| WO (1) | WO2006069373A2 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7335362B2 (en) * | 2002-07-19 | 2008-02-26 | Beth Israel Deaconess Medical Center | Methods of treating pre-eclampsia or eclampsia |
| DK2308507T3 (da) * | 2002-07-19 | 2015-04-20 | Beth Israel Hospital | Fremgangsmåder til behandling af præeklampsi |
| US7435419B2 (en) * | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
| US8273383B2 (en) * | 2004-05-04 | 2012-09-25 | Children's Medical Center Corporation | Methods and compositions for treatment of preeclampsia |
| US7740849B2 (en) | 2004-09-24 | 2010-06-22 | Beth Israel Deaconess Medical Center | Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders |
| DK1804836T3 (da) | 2004-09-24 | 2011-01-24 | Beth Israel Hospital | Fremgangsmåder til diagnosticering og behandling af graviditetskomplikationer |
| JP2008523816A (ja) | 2004-12-15 | 2008-07-10 | ベス イスラエル ディーコネス メディカル センター | 妊娠合併症の診断および処置に有用な核酸およびポリペプチド |
| ATE519109T1 (de) * | 2004-12-21 | 2011-08-15 | Univ Yale | Präeklampsie-diagnose |
| US20060257901A1 (en) * | 2005-03-24 | 2006-11-16 | Beth Israel Deaconess Medical Center | Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy |
| EP1946121A2 (de) | 2005-10-27 | 2008-07-23 | Yale University, Inc. | Proteomische harn-biomarkermuster bei präeklampsie |
| US20070111326A1 (en) * | 2005-11-14 | 2007-05-17 | Abbott Laboratories | Diagnostic method for proteinaceous binding pairs, cardiovascular conditions and preeclampsia |
| US20090286271A1 (en) * | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| US20080071151A1 (en) * | 2006-06-30 | 2008-03-20 | Sogin David C | Method and Apparatus for Diagnosing Pre-eclampsia |
| DE602006015964D1 (de) * | 2006-09-20 | 2010-09-16 | Roche Diagnostics Gmbh | Natriurethische Peptide und Plazenta-Wachstumfaktor/löslicher VEGF-Rezeptor unterscheiden zwischen mit der Plazenta verbundener Herzdysfunktion und mit Herzerkrankung verbundener Herzdysfunktion |
| WO2008075363A1 (en) | 2006-12-20 | 2008-06-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Variants of vegfr and their use in the diagnosis and treatment of pregnancy associated medical conditions |
| CN101259119B (zh) * | 2007-03-08 | 2010-05-19 | 上海市计划生育科学研究所 | 一种丝氨酸蛋白酶抑制剂及其衍生物在生育调节中的应用 |
| US8835183B2 (en) | 2008-01-07 | 2014-09-16 | Ortho-Clinical Diagnostics, Inc. | Determination of sFlt-1:angiogenic factor complex |
| US8148157B2 (en) | 2008-01-07 | 2012-04-03 | Ortho-Clinical Diagnostics, Inc. | Reference, calibrator, or control composition of PIGF-1 and sFlt-1 |
| WO2009094665A1 (en) * | 2008-01-25 | 2009-07-30 | Perkinelmer Health Sciences, Inc. | Methods for determining the risk of prenatal complications |
| WO2009108073A1 (en) * | 2008-02-28 | 2009-09-03 | Auckland Uniservices Limited | Biomarkers for prediction of preeclampsia and/or cardiovascular disease |
| WO2010062377A2 (en) * | 2008-10-31 | 2010-06-03 | Yale University | Methods and compositions for the detection and treatment of preeclampsia |
| MX2011005454A (es) * | 2008-11-24 | 2011-06-20 | Corthera Inc | Prediccion y prevencion de preeclampsia. |
| WO2010091253A1 (en) | 2009-02-06 | 2010-08-12 | Women & Infants' Hospital Of Rhode Island | Compositions, formulations and methods of treating preeclampsia-type disorders of pregnancy |
| CN101643785B (zh) * | 2009-06-18 | 2011-12-21 | 中国人民解放军第二军医大学 | 用于妊娠高血压综合症检测的hsa-mir-210试剂盒及检测方法 |
| WO2011128357A2 (en) * | 2010-04-13 | 2011-10-20 | Pronota N.V. | Biomarkers for hypertensive disorders of pregnancy |
| US20110251094A1 (en) | 2010-04-13 | 2011-10-13 | Pronota N.V. | Biomarkers for hypertensive disorders of pregnancy |
| US8969322B2 (en) | 2010-05-14 | 2015-03-03 | Beth Israel Deconess Medical Center, Inc. | Extracorporeal devices and methods of treating complications of pregnancy |
| CA2886489A1 (en) | 2011-10-14 | 2013-04-18 | Aarhus Universitet | Diagnostic and prognostic use of prombp-complexes |
| US20150087553A1 (en) * | 2012-04-13 | 2015-03-26 | Bioscreening and Diagnostics, LLC | Early trimester screening for early- and late-onset preeclampsia |
| HK1206790A1 (en) * | 2012-05-08 | 2016-01-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for providing a preeclampsia assessment |
| SG11201407667UA (en) | 2012-06-27 | 2015-02-27 | Hoffmann La Roche | MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD |
| SG11201501065QA (en) * | 2012-09-04 | 2015-03-30 | Pluristem Ltd | Methods for prevention and treatment of preeclampsia |
| RU2519083C1 (ru) * | 2012-10-29 | 2014-06-10 | Федеральное государственное бюджетное учреждение "Уральский научно-исследовательский институт охраны материнства и младенчества" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "НИИ ОММ" Минздравсоцразвития России) | Способ прогноза гипертензионных осложнений беременности у пациенток с гестационным сахарным диабетом |
| GB201303649D0 (en) | 2013-03-01 | 2013-04-17 | Univ Aston | Hydrogen sulphide compounds |
| CN103207274B (zh) * | 2013-04-28 | 2015-02-25 | 成都中医药大学 | 一种胎儿7号染色体异常疾病的筛查试剂盒 |
| CN105917233B (zh) | 2014-01-24 | 2018-07-03 | 豪夫迈·罗氏有限公司 | 产后hellp综合征、产后子痫或产后子痫前期的预测 |
| FR3017955B1 (fr) * | 2014-02-27 | 2018-04-06 | Assistance Publique - Hopitaux De Paris | Biomarqueurs diagnostics de la cardiomyopathie du peripartum |
| CA3157573C (en) | 2014-04-10 | 2025-11-18 | Yale University | METHODS AND COMPOSITIONS FOR DETECTING MISFOLDED PROTEINS |
| EP3175239A1 (de) * | 2014-07-30 | 2017-06-07 | Matthew Cooper | Verfahren und zusammensetzungen zur diagnose, prognose und bestätigung von präeklampsie |
| WO2016132136A1 (en) * | 2015-02-18 | 2016-08-25 | Aston University | Diagnostic assay and treatment for preeclampsia |
| CN108700591A (zh) * | 2015-09-11 | 2018-10-23 | 洛斯安第斯大学 | 用于鉴定妊娠相关疾病的体外方法 |
| CL2018000664A1 (es) | 2015-09-11 | 2019-02-08 | Univ Los Andes | Método in vitro para identificar una enfermedad relacionada con el embarazo |
| CN107884570A (zh) * | 2016-09-29 | 2018-04-06 | 韦彦余 | 一种孕妇先兆子痫检测试剂盒 |
| CN109891239B (zh) * | 2016-10-24 | 2022-04-05 | 苏州爱尔迪思生物科技有限公司 | 用于提供子痫前期评估和预测早产的方法和试剂盒 |
| EP3559253A4 (de) * | 2016-12-20 | 2020-08-26 | Sangui Bio Pty. Ltd | Blutprofilerstellung mit proteaseinhibitoren |
| CN111094988A (zh) | 2017-09-13 | 2020-05-01 | 普罗根尼蒂公司 | 先兆子痫生物标志物及相关系统和方法 |
| CN109557320A (zh) * | 2018-11-26 | 2019-04-02 | 余波澜 | 辅助检测胎盘植入的试剂盒及其应用 |
| EP4070113A4 (de) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor |
| US12436155B2 (en) | 2020-04-16 | 2025-10-07 | Kalia Health, Inc. | Preeclampsia screening device and methods measuring activin and/or inhibin A |
| US20230298758A1 (en) * | 2020-11-06 | 2023-09-21 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and Methods for Evaluating Gestational Progress and Applications Thereof |
| US20220298364A1 (en) | 2021-03-18 | 2022-09-22 | The Patent Well LLC | Corrosion-Inhibiting Coatings for Metal Mesh Gaskets and Metallic Particles |
| AU2022405688A1 (en) | 2021-12-08 | 2024-06-06 | B.R.A.H.M.S Gmbh | Biomarkers for prognosis of early onset preeclampsia |
| AU2023390798A1 (en) | 2022-12-08 | 2025-06-12 | B.R.A.H.M.S Gmbh | Multiple sflt-1 measurements for prognosis of early onset preeclampsia |
| CN116953255A (zh) * | 2023-07-27 | 2023-10-27 | 山东大学 | 血清中总IgM和/或总IgG在子痫前期预测或诊断中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| US5998216A (en) | 1996-10-01 | 1999-12-07 | Beth Israel Deaconess Medical Center | Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen |
| WO1998028006A1 (en) | 1996-12-23 | 1998-07-02 | Cambridge University Technical Services Limited | Diagnosis and treatment of pathological pregnancies |
| CA2430889A1 (en) * | 2002-06-19 | 2003-12-19 | Bayer Corporation | Stabilization of brain natriuretic peptide (bnp) in blood samples, methods and compositions related thereto |
| EP1515997A1 (de) | 2002-06-21 | 2005-03-23 | ExxonMobil Chemical Patents Inc. | Ethylen- polymerisationskatalysator basiert auf yttrium mit amidinate als sperrige zusätzliche liganden |
| DK2308507T3 (da) * | 2002-07-19 | 2015-04-20 | Beth Israel Hospital | Fremgangsmåder til behandling af præeklampsi |
| DK1388734T3 (da) * | 2002-08-01 | 2004-05-03 | Mtm Lab Ag | Metode til opløsningsbaseret diagnose |
| AU2003288027A1 (en) * | 2002-11-16 | 2004-06-15 | Dade Behring Marburg Gmbh | Scd40l, papp-a and placental growth factor (plgf) used as a biochemical marker combination in cardiovascular diseases |
| JP2008523816A (ja) | 2004-12-15 | 2008-07-10 | ベス イスラエル ディーコネス メディカル センター | 妊娠合併症の診断および処置に有用な核酸およびポリペプチド |
| ATE519109T1 (de) * | 2004-12-21 | 2011-08-15 | Univ Yale | Präeklampsie-diagnose |
| EP1946121A2 (de) | 2005-10-27 | 2008-07-23 | Yale University, Inc. | Proteomische harn-biomarkermuster bei präeklampsie |
-
2005
- 2005-12-21 AT AT05857213T patent/ATE519109T1/de not_active IP Right Cessation
- 2005-12-21 EP EP05857213A patent/EP1839056B1/de not_active Expired - Lifetime
- 2005-12-21 ES ES11176350.4T patent/ES2475975T3/es not_active Expired - Lifetime
- 2005-12-21 CN CN200580047028.XA patent/CN101163970A/zh active Pending
- 2005-12-21 US US11/314,073 patent/US7727733B2/en active Active
- 2005-12-21 JP JP2007548575A patent/JP5009811B2/ja not_active Expired - Lifetime
- 2005-12-21 WO PCT/US2005/047010 patent/WO2006069373A2/en not_active Ceased
- 2005-12-21 ES ES05857213T patent/ES2371084T3/es not_active Expired - Lifetime
- 2005-12-21 EP EP11176350.4A patent/EP2434283B1/de not_active Expired - Lifetime
-
2010
- 2010-05-17 US US12/781,474 patent/US7935496B2/en not_active Expired - Lifetime
-
2011
- 2011-03-21 US US13/053,045 patent/US8871448B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7935496B2 (en) | 2011-05-03 |
| EP2434283A3 (de) | 2012-07-11 |
| CN101163970A (zh) | 2008-04-16 |
| JP2008524635A (ja) | 2008-07-10 |
| US8871448B2 (en) | 2014-10-28 |
| WO2006069373A2 (en) | 2006-06-29 |
| JP5009811B2 (ja) | 2012-08-22 |
| WO2006069373A8 (en) | 2006-09-14 |
| EP1839056B1 (de) | 2011-08-03 |
| EP1839056A4 (de) | 2008-05-21 |
| EP1839056A2 (de) | 2007-10-03 |
| EP2434283A2 (de) | 2012-03-28 |
| EP2434283B1 (de) | 2014-03-26 |
| US20100227342A1 (en) | 2010-09-09 |
| US20120040371A1 (en) | 2012-02-16 |
| WO2006069373A3 (en) | 2006-11-23 |
| US20060183175A1 (en) | 2006-08-17 |
| ES2475975T3 (es) | 2014-07-11 |
| US7727733B2 (en) | 2010-06-01 |
| ES2371084T3 (es) | 2011-12-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE519109T1 (de) | Präeklampsie-diagnose | |
| WO2004089187A3 (en) | Caries risk test for predicting and assessing the risk of disease | |
| Tripodi et al. | High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism | |
| Jenner | Serum free light chains in clinical laboratory diagnostics | |
| CA3157573C (en) | METHODS AND COMPOSITIONS FOR DETECTING MISFOLDED PROTEINS | |
| ATE452343T1 (de) | Verbesserte vitamin-d-messung | |
| ATE395812T1 (de) | Methoden zur vorhersage eines schwangerschaftsergebnisses bei einer testperson mit hilfe eines hcg-tests | |
| WO2009137015A3 (en) | Biomarkers of ionizing radiation | |
| ATE536553T1 (de) | Verfahren zum nachweis grösserer ungünstiger kardiovaskulärer und zerebrovaskulärer ereignisse | |
| Giavarina et al. | Reference interval of D-dimer in pregnant women | |
| ATE438860T1 (de) | P1gf und flt-1 als prognostische parameter bei kardiovaskulären erkrankungen | |
| CN102224422A (zh) | 使用pigf-2和pigf-3标志物确定先兆子痫风险的方法 | |
| EP2287618A3 (de) | Verfahren zur Diagnose neurodegenerativer Erkrankungen | |
| NO20050186L (no) | Oligosakkaridbiomarkorer for mucopolysakkaridoser og andre beslektede forstyrrelser | |
| WO2003023352A3 (en) | Saliva-based methods for preventing and assessing the risk of diseases | |
| MX2012002797A (es) | Panel multimarcador para hipertrofia ventricular izquierda. | |
| JP2018536170A5 (de) | ||
| Cavalier et al. | Establishment of reference values in a healthy population and interpretation of serum PTH concentrations in hemodialyzed patients according to the KDIGO Guidelines using the Lumipulse® G whole PTH (3rd generation) assay | |
| WO2005071407A3 (en) | Methods of diagnosing acute coronary syndrome by measuring urotensin ii | |
| Pipkin et al. | Predicting high blood pressure in pregnancy: a multivariate approach | |
| ATE420364T1 (de) | Verfahren zur magenkrebsvorhersage | |
| DE60126991D1 (de) | Verfahren ZUR DIAGNOSE VON SCHIZOPHRENIE | |
| Nerenz et al. | Estimating the hCGβcf in urine during pregnancy | |
| CA2523690A1 (en) | Use of protein masp as a marker for colorectal cancer | |
| Bonebrake et al. | Is fluorescence polarization reliable and cost efficient in a fetal lung maturity cascade? |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |