ATE519109T1 - Präeklampsie-diagnose - Google Patents

Präeklampsie-diagnose

Info

Publication number
ATE519109T1
ATE519109T1 AT05857213T AT05857213T ATE519109T1 AT E519109 T1 ATE519109 T1 AT E519109T1 AT 05857213 T AT05857213 T AT 05857213T AT 05857213 T AT05857213 T AT 05857213T AT E519109 T1 ATE519109 T1 AT E519109T1
Authority
AT
Austria
Prior art keywords
pregnancy
preeclampsia
risk
levels
present
Prior art date
Application number
AT05857213T
Other languages
English (en)
Inventor
Irina Buhimschi
Catalin Buhimschi
Errol Norwitz
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Application granted granted Critical
Publication of ATE519109T1 publication Critical patent/ATE519109T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/321—Arterial hypertension
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05857213T 2004-12-21 2005-12-21 Präeklampsie-diagnose ATE519109T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63794804P 2004-12-21 2004-12-21
PCT/US2005/047010 WO2006069373A2 (en) 2004-12-21 2005-12-21 Diagnosis of preeclampsia

Publications (1)

Publication Number Publication Date
ATE519109T1 true ATE519109T1 (de) 2011-08-15

Family

ID=36602368

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05857213T ATE519109T1 (de) 2004-12-21 2005-12-21 Präeklampsie-diagnose

Country Status (7)

Country Link
US (3) US7727733B2 (de)
EP (2) EP1839056B1 (de)
JP (1) JP5009811B2 (de)
CN (1) CN101163970A (de)
AT (1) ATE519109T1 (de)
ES (2) ES2475975T3 (de)
WO (1) WO2006069373A2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7435419B2 (en) 2002-07-19 2008-10-14 Beth Israel Deaconess Medical Center Methods of diagnosing and treating pre-eclampsia or eclampsia
US7335362B2 (en) 2002-07-19 2008-02-26 Beth Israel Deaconess Medical Center Methods of treating pre-eclampsia or eclampsia
PT2308507E (pt) 2002-07-19 2015-05-11 Beth Israel Hospital Métodos de tratamento de pré-eclâmpsia
EP1773349A4 (de) 2004-05-04 2009-07-29 Childrens Medical Center Verfahren und zusammensetzungen zur behandlung von präeklampsie
US20060067937A1 (en) * 2004-09-24 2006-03-30 Karumanchi S A Methods of diagnosing and treating complications of pregnancy
US7740849B2 (en) 2004-09-24 2010-06-22 Beth Israel Deaconess Medical Center Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders
DE602005023216D1 (de) 2004-12-15 2010-10-07 Beth Israel Hospital Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen
JP5009811B2 (ja) * 2004-12-21 2012-08-22 イェール ユニバーシティ 子癇前症の検出
EP1866441A4 (de) * 2005-03-24 2009-11-11 Beth Israel Hospital Verfahren zur diagnose von trisomie 13 beim fötus oder des risikos von trisomie 13 beim fötus während der schwangerschaft
WO2007051069A2 (en) * 2005-10-27 2007-05-03 Yale University Urinary proteomic biomarker patterns in preeclampsia
US20070111326A1 (en) * 2005-11-14 2007-05-17 Abbott Laboratories Diagnostic method for proteinaceous binding pairs, cardiovascular conditions and preeclampsia
US20090286271A1 (en) * 2006-05-31 2009-11-19 Karumanchi Ananth S Methods of Diagnosing and Treating Complications of Pregnancy
US20080071151A1 (en) * 2006-06-30 2008-03-20 Sogin David C Method and Apparatus for Diagnosing Pre-eclampsia
EP1903339B1 (de) * 2006-09-20 2010-08-04 Roche Diagnostics GmbH Natriurethische Peptide und Plazenta-Wachstumfaktor/löslicher VEGF-Rezeptor unterscheiden zwischen mit der Plazenta verbundener Herzdysfunktion und mit Herzerkrankung verbundener Herzdysfunktion
EP2099913B1 (de) * 2006-12-20 2012-02-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Vegfr-varianten und deren verwendung bei der diagnose und behandlung von mit schwangerschaft assoziierten medizinischen leiden
CN101259119B (zh) * 2007-03-08 2010-05-19 上海市计划生育科学研究所 一种丝氨酸蛋白酶抑制剂及其衍生物在生育调节中的应用
RU2523887C2 (ru) * 2008-01-07 2014-07-27 Орто-Клиникал Дайэгностикс, Инк. Калибратор/регулятор для синхронного анализа белков, способных к комплексообразованию друг с другом
EP2235529B1 (de) 2008-01-07 2016-12-14 Ortho-Clinical Diagnostics, Inc. Bestimmung des sflt-1:angiogenesefaktorkomplexes
WO2009094665A1 (en) * 2008-01-25 2009-07-30 Perkinelmer Health Sciences, Inc. Methods for determining the risk of prenatal complications
WO2009108073A1 (en) * 2008-02-28 2009-09-03 Auckland Uniservices Limited Biomarkers for prediction of preeclampsia and/or cardiovascular disease
CN104777308B (zh) * 2008-10-31 2017-04-12 耶鲁大学 先兆子痫检测和治疗的方法和组合物
WO2010060102A2 (en) * 2008-11-24 2010-05-27 Corthera, Inc. Prediction and prevention of preeclampsia
WO2010091253A1 (en) 2009-02-06 2010-08-12 Women & Infants' Hospital Of Rhode Island Compositions, formulations and methods of treating preeclampsia-type disorders of pregnancy
CN101643785B (zh) * 2009-06-18 2011-12-21 中国人民解放军第二军医大学 用于妊娠高血压综合症检测的hsa-mir-210试剂盒及检测方法
WO2011128357A2 (en) * 2010-04-13 2011-10-20 Pronota N.V. Biomarkers for hypertensive disorders of pregnancy
US20110251094A1 (en) 2010-04-13 2011-10-13 Pronota N.V. Biomarkers for hypertensive disorders of pregnancy
JP5959506B2 (ja) * 2010-05-14 2016-08-02 ベス イスラエル デアコネス メディカル センター インコーポレイテッド 妊娠合併症を治療するための体外デバイスおよび方法
WO2013053359A1 (en) 2011-10-14 2013-04-18 Aarhus Universitet Diagnostic and prognostic use of prombp-complexes
WO2013155458A1 (en) * 2012-04-13 2013-10-17 Wayne State University Early trimester screening for early- and late-onset preeclampsia
US20150099655A1 (en) * 2012-05-08 2015-04-09 The Board Of Trustees Of The Leland Stanford Junior University Methods and Compositions for Providing a Preeclampsia Assessment
CA2871878C (en) 2012-06-27 2021-08-10 F. Hoffmann-La Roche Ag Means and methods applying sflt-1/pigf or endoglin/pigf ratio to rule-out onset of preeclampsia within a certain time period
US9950014B2 (en) * 2012-09-04 2018-04-24 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
RU2519083C1 (ru) * 2012-10-29 2014-06-10 Федеральное государственное бюджетное учреждение "Уральский научно-исследовательский институт охраны материнства и младенчества" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "НИИ ОММ" Минздравсоцразвития России) Способ прогноза гипертензионных осложнений беременности у пациенток с гестационным сахарным диабетом
GB201303649D0 (en) 2013-03-01 2013-04-17 Univ Aston Hydrogen sulphide compounds
CN103207274B (zh) * 2013-04-28 2015-02-25 成都中医药大学 一种胎儿7号染色体异常疾病的筛查试剂盒
CA2936883C (en) * 2014-01-24 2022-06-28 Martin Hund Prediction of postpartum hellp syndrome, postpartum eclampsia or postpartum preeclampsia
FR3017955B1 (fr) * 2014-02-27 2018-04-06 Assistance Publique - Hopitaux De Paris Biomarqueurs diagnostics de la cardiomyopathie du peripartum
EP3129779B1 (de) 2014-04-10 2020-06-03 Yale University Verfahren und zusammensetzungen zur detektion von falsch gefalteten proteinen
CA2956646A1 (en) * 2014-07-30 2016-02-04 Matthew Cooper Methods and compositions for diagnosing, prognosing, and confirming preeclampsia
EP3259600A1 (de) 2015-02-18 2017-12-27 Aston University Diagnostischer assay und behandlung von präeklampsie
CL2018000664A1 (es) 2015-09-11 2019-02-08 Univ Los Andes Método in vitro para identificar una enfermedad relacionada con el embarazo
JP2018536170A (ja) 2015-09-11 2018-12-06 ウニベルシダッド デ ロス アンデス 妊娠関連疾患を同定するｉｎ ｖｉｔｒｏ方法
CN107884570A (zh) * 2016-09-29 2018-04-06 韦彦余 一种孕妇先兆子痫检测试剂盒
CN109891239B (zh) * 2016-10-24 2022-04-05 苏州爱尔迪思生物科技有限公司 用于提供子痫前期评估和预测早产的方法和试剂盒
AU2017379367B2 (en) * 2016-12-20 2023-12-07 Sangui Bio Pty. Ltd Blood profiling with protease inhibitors
MX2020002788A (es) 2017-09-13 2020-09-14 Progenity Inc Biomarcadores de preeclampsia y sistemas y metodos relacionados.
CN109557320A (zh) * 2018-11-26 2019-04-02 余波澜 辅助检测胎盘植入的试剂盒及其应用
EP4070113A4 (de) 2019-12-04 2023-12-20 Biora Therapeutics, Inc. Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor
CA3152815A1 (en) 2021-03-18 2022-09-18 The Patent Well, Llc Film forming compositions containing molybdate derived coatings
AU2022405688A1 (en) 2021-12-08 2024-06-06 B.R.A.H.M.S Gmbh Biomarkers for prognosis of early onset preeclampsia
WO2024121392A1 (en) 2022-12-08 2024-06-13 B.R.A.H.M.S Gmbh Multiple sflt-1 measurements for prognosis of early onset preeclampsia
CN116953255A (zh) * 2023-07-27 2023-10-27 山东大学 血清中总IgM和/或总IgG在子痫前期预测或诊断中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US5998216A (en) 1996-10-01 1999-12-07 Beth Israel Deaconess Medical Center Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen
CA2275708A1 (en) 1996-12-23 1998-07-02 Cambridge University Technical Services Limited Diagnosis and treatment of pathological pregnancies
CA2430889A1 (en) * 2002-06-19 2003-12-19 Bayer Corporation Stabilization of brain natriuretic peptide (bnp) in blood samples, methods and compositions related thereto
WO2004000894A1 (en) 2002-06-21 2003-12-31 Exxonmobil Chemical Patents Inc. Yttrium-based ethylene polymerization catalysts with bulky amidinate ancillary ligands
PT2308507E (pt) * 2002-07-19 2015-05-11 Beth Israel Hospital Métodos de tratamento de pré-eclâmpsia
ES2215957T3 (es) * 2002-08-01 2004-10-16 Mtm Laboratories Ag Metodo para diagnostico basado en una solucion.
EP1962096B1 (de) * 2002-11-16 2012-07-18 Siemens Healthcare Diagnostics Products GmbH SCD40L, PAPP-A und plazentaler-Wachstumsfaktor (PIGF) als biochemische Markerkombination bei kardiovaskulären Erkrankungen
DE602005023216D1 (de) * 2004-12-15 2010-10-07 Beth Israel Hospital Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen
JP5009811B2 (ja) * 2004-12-21 2012-08-22 イェール ユニバーシティ 子癇前症の検出
WO2007051069A2 (en) 2005-10-27 2007-05-03 Yale University Urinary proteomic biomarker patterns in preeclampsia

Also Published As

Publication number Publication date
EP2434283A2 (de) 2012-03-28
EP1839056A2 (de) 2007-10-03
CN101163970A (zh) 2008-04-16
ES2371084T3 (es) 2011-12-27
US7935496B2 (en) 2011-05-03
US8871448B2 (en) 2014-10-28
EP2434283B1 (de) 2014-03-26
JP2008524635A (ja) 2008-07-10
US20120040371A1 (en) 2012-02-16
JP5009811B2 (ja) 2012-08-22
EP1839056A4 (de) 2008-05-21
WO2006069373A2 (en) 2006-06-29
US7727733B2 (en) 2010-06-01
WO2006069373A3 (en) 2006-11-23
ES2475975T3 (es) 2014-07-11
US20060183175A1 (en) 2006-08-17
US20100227342A1 (en) 2010-09-09
WO2006069373A8 (en) 2006-09-14
EP1839056B1 (de) 2011-08-03
EP2434283A3 (de) 2012-07-11

Similar Documents

Publication Publication Date Title
ATE519109T1 (de) Präeklampsie-diagnose
WO2005017192A3 (en) Screening for gestational disorders
WO2004089187A3 (en) Caries risk test for predicting and assessing the risk of disease
AU2015243171B2 (en) Methods and compositions for detecting misfolded proteins
DE60025347D1 (de) Methoden zur vohersage eines schwangerschaftsergebnisses bei einer testperson mit hilfe eines hcg-tests
ATE452343T1 (de) Verbesserte vitamin-d-messung
Hoskin et al. Elevated sex-hormone binding globulin in elderly women with Alzheimer’s disease
EP2293075A3 (de) Verfahren zur Diagnose neurodegenerativer Erkrankungen
WO2009152607A8 (en) Methods and kits for diagnosing neurodegenerative disease
WO2009137015A3 (en) Biomarkers of ionizing radiation
Laughlin-Tommaso et al. Cardiovascular risk factors and diseases in women undergoing hysterectomy with ovarian conservation
ATE536553T1 (de) Verfahren zum nachweis grösserer ungünstiger kardiovaskulärer und zerebrovaskulärer ereignisse
WO2004046729A3 (en) Bodily fluid markers of tissue hypoxia
WO1999041584A3 (en) METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY hCG ASSAY
WO2005071407A3 (en) Methods of diagnosing acute coronary syndrome by measuring urotensin ii
CA2701341A1 (en) Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex
JP2018536170A5 (de)
Singhal et al. Correlation of 2 hour, 4 hour, 8 hour and 12 hour urine protein with 24 hour urinary protein in preeclampsia
ATE420364T1 (de) Verfahren zur magenkrebsvorhersage
Nerenz et al. Estimating the hCGβcf in urine during pregnancy
Hertweck et al. Ferriman-Gallwey scores, serum androgen and mullerian inhibiting substance levels in hirstute adolescent girls
DE60126991D1 (de) Verfahren ZUR DIAGNOSE VON SCHIZOPHRENIE
Moiety et al. Albumin to creatinine ratio in a random urine sample: Correlation with severity of preeclampsia
EP2726631A1 (de) Verfahren zur diagnose von präeklampsie
Bonebrake et al. Is fluorescence polarization reliable and cost efficient in a fetal lung maturity cascade?

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties