CA2928969C - Compositions and methods for ophthalmic and/or other applications - Google Patents
Compositions and methods for ophthalmic and/or other applications Download PDFInfo
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- CA2928969C CA2928969C CA2928969A CA2928969A CA2928969C CA 2928969 C CA2928969 C CA 2928969C CA 2928969 A CA2928969 A CA 2928969A CA 2928969 A CA2928969 A CA 2928969A CA 2928969 C CA2928969 C CA 2928969C
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- loteprednol etabonate
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
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- A—HUMAN NECESSITIES
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- A61K9/513—Organic macromolecular compounds; Dendrimers
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Landscapes
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| US8889193B2 (en) | 2010-02-25 | 2014-11-18 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
| US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
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| EP3808339B1 (en) | 2012-05-03 | 2025-11-12 | Alcon Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US11596599B2 (en) * | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US10864219B2 (en) * | 2012-05-03 | 2020-12-15 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| EP4008355A1 (en) | 2012-05-03 | 2022-06-08 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US9889208B2 (en) | 2012-05-04 | 2018-02-13 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
| US10568975B2 (en) | 2013-02-05 | 2020-02-25 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| US20180071215A1 (en) * | 2013-12-18 | 2018-03-15 | Massachusetts Institute Of Technology | Core-shell particles for controlled release |
| CA2974715C (en) | 2015-01-27 | 2020-05-05 | The Johns Hopkins University | Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces |
| KR101938284B1 (ko) * | 2015-06-15 | 2019-01-15 | 주식회사 엘지화학 | 형광 복합체, 광전환 필름, 광전환 소자 및 이를 포함하는 디스플레이 장치 |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| US11529309B2 (en) * | 2016-04-29 | 2022-12-20 | University Of Houston System | Compositions, methods and kits for treating a contact lens |
| EP3448389B1 (en) | 2016-06-27 | 2021-09-29 | Achillion Pharmaceuticals, Inc. | Quinazoline and indole compounds to treat medical disorders |
| CA3036474A1 (en) | 2016-09-13 | 2018-03-22 | Kyowa Hakko Kirin Co., Ltd. | Therapeutic agent for an ophthalmic disease comprising a vegf receptor inhibitor |
| CA3037176A1 (en) * | 2016-09-16 | 2018-03-22 | Kala Pharmaceuticals, Inc. | Particles, compositions, and methods for ophthalmic and/or other applications |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| WO2019113425A1 (en) * | 2017-12-08 | 2019-06-13 | The Johns Hopkins University | Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces |
| CN111712468A (zh) | 2017-12-22 | 2020-09-25 | 北卡罗莱纳州立大学 | 聚合物荧光团、包含其的组合物及制备和使用其的方法 |
| US20200345637A1 (en) * | 2018-01-19 | 2020-11-05 | Aiviva Biopharma, Inc. | Suspension compositions of multi-target inhibitors |
| AU2019272871B2 (en) * | 2018-05-25 | 2025-02-27 | Ads Therapeutics Llc | A composition for treating ocular hyperemia and a method for treating ocular hyperemia with the same |
| JP7538113B2 (ja) | 2018-08-20 | 2024-08-21 | アキリオン ファーマシューティカルズ，インコーポレーテッド | 補体ｄ因子の医学的障害の治療のための医薬化合物 |
| EP3846803A4 (en) | 2018-09-06 | 2022-08-10 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| EP3866773B1 (en) | 2018-10-16 | 2024-08-28 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| KR102261590B1 (ko) * | 2019-01-11 | 2021-06-07 | 한국콜마주식회사 | 수용성 추출물이 흡수된 화장용 캡슐을 포함하는 화장료 조성물 |
| EP3946297A4 (en) | 2019-04-01 | 2023-08-02 | Emory University | HYALURONIC ACID NANOPARTICLES COMPRISING NADPH OXIDASE INHIBITORS AND THEIR USES IN THE TREATMENT OF CANCER |
| US11883525B2 (en) * | 2019-05-31 | 2024-01-30 | Dose Medical Corporation | Bioerodible polyester polymer axitinib ocular implants and related methods of use |
| CN114245737A (zh) * | 2019-06-11 | 2022-03-25 | 司斐股份有限公司 | 微乳剂组合物 |
| US11426351B2 (en) * | 2019-12-26 | 2022-08-30 | Sunstar Inc. | Process for producing a pharmaceutical composition containing micro particles |
| CN115362162A (zh) | 2020-02-20 | 2022-11-18 | 艾其林医药公司 | 用于治疗补体因子d介导的障碍的杂芳基化合物 |
| WO2021222913A1 (en) * | 2020-04-30 | 2021-11-04 | Koziol Jeffrey E | Micro dosing of viral vaccines |
| US20230248689A1 (en) * | 2020-06-26 | 2023-08-10 | Purdue Research Foundation | Pharmaceutical formulations of griseofulvin for long-term ocular delivery |
| CN116437913A (zh) | 2020-09-23 | 2023-07-14 | 艾其林医药公司 | 用于治疗补体介导的病症的药物化合物 |
| US12186512B2 (en) * | 2020-10-26 | 2025-01-07 | Christopher Green | Treatment for dry eyes |
| AU2022218993A1 (en) | 2021-02-10 | 2023-08-03 | Iolyx Therapeutics, Inc. | Methods for ophthalmic delivery of roflumilast |
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| CN118141743A (zh) * | 2024-02-07 | 2024-06-07 | 中山大学 | 一种眼部注射制剂及其应用 |
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