CA2921226A1 - Devices, systems, methods and kits for receiving a swab - Google Patents
Devices, systems, methods and kits for receiving a swab Download PDFInfo
- Publication number
- CA2921226A1 CA2921226A1 CA2921226A CA2921226A CA2921226A1 CA 2921226 A1 CA2921226 A1 CA 2921226A1 CA 2921226 A CA2921226 A CA 2921226A CA 2921226 A CA2921226 A CA 2921226A CA 2921226 A1 CA2921226 A1 CA 2921226A1
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- CA
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- Prior art keywords
- swab
- less
- reagent
- container
- cartridge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ584963A (en) | 2007-10-02 | 2012-11-30 | Theranos Inc | Modular Point-of-care devices as addressible assay units with tips of assay units having interior to immobilize reagents by capillary action |
WO2012100235A2 (en) | 2011-01-21 | 2012-07-26 | Theranos, Inc. | Systems and methods for sample use maximization |
US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
US8840838B2 (en) | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
US10946376B2 (en) * | 2013-07-05 | 2021-03-16 | Thinxxs Microtechnology Ag | Carrier element for introducing a dry substance into a flow cell |
KR20160053979A (ko) | 2013-09-06 | 2016-05-13 | 테라노스, 인코포레이티드 | 전염성 질환의 검출을 위한 시스템 및 방법 |
MX384530B (es) | 2013-09-06 | 2025-03-14 | Labrador Diagnostics Llc | Dispositivos, sistemas, metodos y equipos para recibir un hisopo. |
CA3021198C (en) * | 2015-04-17 | 2024-01-16 | Innovaprep Llc | Surface sampling with swab and pressurized foam |
ES1139582Y (es) * | 2015-05-13 | 2015-08-24 | Servicio Andaluz De Salud | Tapa para el corte de muestras |
WO2018060421A1 (en) * | 2016-09-30 | 2018-04-05 | Koninklijke Philips N.V. | System for preparing a sample |
CN109789408B (zh) * | 2016-09-30 | 2021-09-28 | 皇家飞利浦有限公司 | 用于制备样本的系统 |
WO2019060275A1 (en) | 2017-09-21 | 2019-03-28 | Becton, Dickinson And Company | DEMARCATION TEMPLATE FOR DANGEROUS CONTAMINANT TEST |
US11585733B2 (en) * | 2017-09-21 | 2023-02-21 | Becton, Dickinson And Company | Hazardous contaminant collection kit and rapid testing |
CN111278987B (zh) * | 2017-09-21 | 2024-02-23 | 贝克顿·迪金森公司 | 以高拾取和脱落效率收集有害污染物的采样系统和技术 |
USD859683S1 (en) | 2017-09-21 | 2019-09-10 | Becton, Dickinson And Company | Collection device |
CA3075773A1 (en) * | 2017-09-21 | 2019-03-28 | Becton, Dickinson And Company | Hazardous contaminant collection kit and rapid testing |
CN108445111B (zh) * | 2018-05-09 | 2025-02-07 | 清华大学 | 用于样品检测的闸机系统及样品检验方法 |
CN119184750A (zh) * | 2018-05-22 | 2024-12-27 | C·R·巴德股份有限公司 | 尿液采样套件及其方法 |
EP3647781B1 (en) | 2018-10-29 | 2024-05-01 | EXIAS Medical GmbH | Measuring cartridge for measuring a liquid sample |
DK180434B1 (en) * | 2019-01-09 | 2021-04-23 | Exseed Health Aps | Container for sample collection |
AU2020215639B2 (en) | 2019-01-28 | 2025-08-21 | Becton, Dickinson And Company | Hazardous contaminant collection device with integrated swab and test device |
USD950768S1 (en) | 2019-02-22 | 2022-05-03 | Bioplast Manufacturing, LLC | Collection and transport device |
US12114840B2 (en) * | 2019-03-15 | 2024-10-15 | Sapphiros Laboratories Llc | DNA collection device |
EP3789052A1 (en) * | 2019-09-03 | 2021-03-10 | Smith & Nephew, Inc. | Fibrin clot preparation instruments and method |
CN110772341A (zh) * | 2019-12-11 | 2020-02-11 | 河南温迪生物科技研究院有限公司 | 用于实验研究的快速无创鼻粘液采样盒及其使用方法和应用 |
KR20220166297A (ko) * | 2020-04-03 | 2022-12-16 | 케노타 인크. | 흐름 분석 카트리지 |
CN112472140B (zh) * | 2020-05-11 | 2025-01-14 | 广州达安基因股份有限公司 | 一种采样拭子用保存管 |
WO2021252810A1 (en) | 2020-06-10 | 2021-12-16 | Checkable Medical Incorporated | In vitro diagnostic device |
CN111820955B (zh) * | 2020-07-27 | 2021-09-10 | 南方科技大学 | 一种便携式咽拭子采集智能装置 |
WO2022170350A1 (en) * | 2021-02-08 | 2022-08-11 | Exa Health, Inc. | Monitoring sample collection from an orifice |
USD1011851S1 (en) | 2023-09-29 | 2024-01-23 | Ratio Product Lab LLC | Filling tool |
CN120490360B (zh) * | 2025-07-17 | 2025-09-12 | 江苏三吉利化工股份有限公司 | 一种苯二酚气相色谱检验装置 |
Family Cites Families (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4756884A (en) | 1985-08-05 | 1988-07-12 | Biotrack, Inc. | Capillary flow device |
US4803048A (en) * | 1987-04-02 | 1989-02-07 | Nason Frederic L | Laboratory kit |
US5353803A (en) * | 1993-06-18 | 1994-10-11 | Cerra Michael C | Apparatus and method for immediate diagnosis of vaginal yeast infections |
US20060074063A1 (en) | 1995-12-29 | 2006-04-06 | Fernandez-Pol Jose A | Pharmacological agent and method of treatment |
AU746549B2 (en) | 1996-11-20 | 2002-05-02 | Becton Dickinson & Company | Microfabricated isothermal nucleic acid amplification devices and methods |
CA2294294A1 (en) | 1997-07-14 | 1999-01-28 | Abbott Laboratories | Telemedicine |
JP2000146957A (ja) * | 1997-10-13 | 2000-05-26 | Kikkoman Corp | 検体採取具及び拭取検査用器具 |
JPH11142400A (ja) * | 1997-11-07 | 1999-05-28 | Fujirebio Inc | 糞便保存用具 |
RU2147123C1 (ru) | 1998-12-16 | 2000-03-27 | Боев Сергей Федотович | Способ анализа клеточного состава крови по мазку |
US6468474B2 (en) * | 2000-07-06 | 2002-10-22 | Varian, Inc. | Saliva testing and confirmation device |
US6949377B2 (en) | 2001-03-05 | 2005-09-27 | Ho Winston Z | Chemiluminescence-based microfluidic biochip |
US7879293B2 (en) * | 2001-09-28 | 2011-02-01 | Orasure Technologies, Inc. | Sample collector and test device |
CA2462106C (en) * | 2001-10-03 | 2012-05-22 | 20/20 Genesystems, Inc. | Rapid assay, method and system for detecting biowarfare agents |
US7785782B2 (en) | 2002-12-12 | 2010-08-31 | Novartis Vaccines And Diagnostics, Inc. | Device and method for in-line blood testing using biochips |
EP1583950B1 (en) * | 2002-12-26 | 2017-04-05 | Meso Scale Technologies, LLC. | Assay cartridges and methods of using the same |
DK1662987T3 (da) | 2003-09-11 | 2012-02-27 | Theranos Inc | Medicinsk anordning til analytovervågning og lægemiddeltilførsel |
US6991898B2 (en) * | 2003-10-20 | 2006-01-31 | Kimberly-Clark Worldwide, Inc. | Diagnostic test device and method of using same |
CN100594381C (zh) * | 2003-11-14 | 2010-03-17 | 因韦尔尼斯医药瑞士股份有限公司 | 快速检测和保存样本的装置及其使用方法 |
US8105849B2 (en) * | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
WO2005100980A2 (en) | 2004-04-06 | 2005-10-27 | Bio/Data Corporation | Disposable test device with sample volume measurement and mixing methods |
EP3640342A1 (en) | 2004-05-13 | 2020-04-22 | Nanobiosym, Inc. | Nano-pcr: methods and devices for nucleic acid amplification and detection |
US8614101B2 (en) | 2008-05-20 | 2013-12-24 | Rapid Pathogen Screening, Inc. | In situ lysis of cells in lateral flow immunoassays |
KR101381331B1 (ko) | 2005-05-09 | 2014-04-04 | 테라노스, 인코포레이티드 | 현장진료 유체 시스템 및 그 용도 |
TW200712487A (en) | 2005-08-02 | 2007-04-01 | 3M Innovative Properties Co | Apparatus and method for detecting an analyte |
WO2007078850A2 (en) | 2005-12-29 | 2007-07-12 | I-Stat Corporation | Molecular diagnostics amplification system and methods |
US8741230B2 (en) | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
US7972786B2 (en) | 2006-07-07 | 2011-07-05 | Brandeis University | Detection and analysis of influenza virus |
BRPI0717385A2 (pt) | 2006-10-24 | 2013-10-15 | Koninkl Philips Electronics Nv | Dispositivo, aparelho e método para formar imagem de um objeto |
US7910354B2 (en) | 2006-10-27 | 2011-03-22 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
CN101568636A (zh) | 2006-11-02 | 2009-10-28 | 威腾技术公司 | 用于诊断性检测的模块 |
GB0625309D0 (en) * | 2006-12-19 | 2007-01-24 | Inverness Medical Switzerland | Device |
WO2008115632A2 (en) | 2007-02-09 | 2008-09-25 | The Regents Of The University Of California | Method for recombining dna sequences and compositions related thereto |
GB0706281D0 (en) | 2007-03-30 | 2007-05-09 | Guy S And St Thomas Nhs Founda | Apparatus and method for recovering fluid from a fluid absorbing element |
US20090030342A1 (en) * | 2007-07-27 | 2009-01-29 | 3M Innovative Properties Company | Apparatus and method for releasing a sample of material |
US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
NZ584963A (en) * | 2007-10-02 | 2012-11-30 | Theranos Inc | Modular Point-of-care devices as addressible assay units with tips of assay units having interior to immobilize reagents by capillary action |
US9631244B2 (en) | 2007-10-17 | 2017-04-25 | Advanced Liquid Logic, Inc. | Reagent storage on a droplet actuator |
US20090203531A1 (en) | 2008-02-12 | 2009-08-13 | Nurith Kurn | Method for Archiving and Clonal Expansion |
US20100077843A1 (en) * | 2008-03-31 | 2010-04-01 | Doraisamy Loganathan | Substance identification apparatus and methods of using |
US8236503B2 (en) | 2008-11-07 | 2012-08-07 | Sequenta, Inc. | Methods of monitoring conditions by sequence analysis |
EP2389452A2 (en) | 2009-01-21 | 2011-11-30 | Vertex Pharmaceuticals Incorporated | Methods for amplifying hepatitis c virus nucleic acids |
FR2942533B1 (fr) | 2009-02-25 | 2011-06-24 | Altatech Semiconductor | Dispositif et procede d'inspection de plaquettes semi-conductrices |
JP5265492B2 (ja) * | 2009-09-28 | 2013-08-14 | 栄研化学株式会社 | 環境微生物検査用拭き取り器具 |
BR112012009196B1 (pt) | 2009-10-19 | 2021-03-30 | Labrador Diagnostics Llc | Sistema para modelar a progressão de uma doença dentro de uma população |
GB2483077A (en) | 2010-08-25 | 2012-02-29 | Concateno Uk Ltd | Sample testing assay apparatus and method |
WO2012038049A2 (en) | 2010-09-22 | 2012-03-29 | Roche Diagnostics Gmbh | Amplification of distant nucleic acid targets using engineered primers |
US20130243794A1 (en) | 2010-12-03 | 2013-09-19 | Beth Israel Deaconess Medical Center, Inc. | Methods for predicting and treating infection-induced illnesses and predicting the severity of infection-induced illnesses |
WO2012100235A2 (en) | 2011-01-21 | 2012-07-26 | Theranos, Inc. | Systems and methods for sample use maximization |
EP2746395B1 (en) | 2011-09-08 | 2017-11-29 | Kabushiki Kaisha DNAFORM | Primer set, method for amplifying target nucleic acid sequence using same, and method for detecting mutated nucleic acid using same |
US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
US8840838B2 (en) | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
US20130080071A1 (en) | 2011-09-25 | 2013-03-28 | Theranos, Inc., a Delaware Corporation | Systems and methods for sample processing and analysis |
US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
US8435738B2 (en) | 2011-09-25 | 2013-05-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US20130074614A1 (en) | 2011-09-25 | 2013-03-28 | Theranos, Inc., a Delaware Corporation | Container configurations |
US8380541B1 (en) | 2011-09-25 | 2013-02-19 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
SG10201602141QA (en) | 2011-09-25 | 2016-04-28 | Theranos Inc | Systems And Methods For Multi-Analysis |
US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US11249799B2 (en) | 2011-09-26 | 2022-02-15 | Labrador Diagnostics Llc | Methods, systems, and devices for real time execution and optimization of concurrent test protocols on a single device |
US20140335505A1 (en) | 2011-09-25 | 2014-11-13 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US20140308661A1 (en) | 2011-09-25 | 2014-10-16 | Theranos, Inc. | Systems and methods for multi-analysis |
US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
US9994891B2 (en) | 2011-10-11 | 2018-06-12 | Qiagen Gmbh | Sample processing method and sample processing cartridge |
EP3381558A1 (en) | 2012-03-16 | 2018-10-03 | Stat-Diagnostica & Innovation, S.L. | A method for a test cartridge with integrated transfer module |
GB2500658A (en) * | 2012-03-28 | 2013-10-02 | Dna Electronics Ltd | Biosensor device and system |
US9500639B2 (en) | 2012-07-18 | 2016-11-22 | Theranos, Inc. | Low-volume coagulation assay |
JP2015529549A (ja) | 2012-07-18 | 2015-10-08 | セラノス, インコーポレイテッド | 少容積サンプル用の高速小型遠心分離機 |
US9389229B2 (en) | 2012-07-18 | 2016-07-12 | Theranos, Inc. | Methods for detecting and measuring aggregation |
CA2878957A1 (en) | 2012-07-25 | 2014-01-30 | Theranos, Inc. | Image analysis and measurement of biological samples |
WO2014042986A1 (en) | 2012-09-11 | 2014-03-20 | Theranos, Inc. | Information management systems and methods using a biological signature |
US20140342371A1 (en) | 2012-12-05 | 2014-11-20 | Theranos, Inc. | Bodily Fluid Sample Collection and Transport |
US9051599B2 (en) | 2012-12-10 | 2015-06-09 | Theranos, Inc. | Rapid, low-sample-volume cholesterol and triglyceride assays |
US20140170678A1 (en) | 2012-12-17 | 2014-06-19 | Leukodx Ltd. | Kits, compositions and methods for detecting a biological condition |
EP4220120A3 (en) | 2013-02-18 | 2024-01-10 | Labrador Diagnostics LLC | Systems and methods for multi-analysis |
MX390142B (es) | 2013-02-18 | 2025-03-20 | Theranos Inc | Sistemas y metodos para recolectar y transmitir resultados de ensayos |
SG11201506420WA (en) | 2013-02-18 | 2015-09-29 | Theranos Inc | Image analysis and measurement of biological samples |
CA2906824C (en) | 2013-03-15 | 2023-10-03 | Theranos, Inc. | Nucleic acid amplification |
KR20150132481A (ko) | 2013-03-15 | 2015-11-25 | 테라노스, 인코포레이티드 | 핵산 증폭 |
PL2970922T3 (pl) | 2013-03-15 | 2018-06-29 | Theranos, Inc. | Termostabilna ligaza łącząca tępe końce i sposoby jej wykorzystania |
US9359632B2 (en) | 2013-03-15 | 2016-06-07 | Theranos, Inc. | Devices, systems and methods for sample preparation |
MX384530B (es) | 2013-09-06 | 2025-03-14 | Labrador Diagnostics Llc | Dispositivos, sistemas, metodos y equipos para recibir un hisopo. |
KR20160053979A (ko) | 2013-09-06 | 2016-05-13 | 테라노스, 인코포레이티드 | 전염성 질환의 검출을 위한 시스템 및 방법 |
WO2015057743A1 (en) | 2013-10-14 | 2015-04-23 | Theranos, Inc. | Methods and systems for obtaining clinical samples |
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2014
- 2014-09-05 MX MX2016002797A patent/MX384530B/es unknown
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- 2014-09-05 SG SG11201601608TA patent/SG11201601608TA/en unknown
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- 2014-09-05 KR KR1020167008744A patent/KR20160049001A/ko not_active Withdrawn
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CN105683751A (zh) | 2016-06-15 |
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US20150072362A1 (en) | 2015-03-12 |
JP2021120681A (ja) | 2021-08-19 |
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SG11201601608TA (en) | 2016-04-28 |
CN105683751B (zh) | 2020-01-17 |
BR112016004955B1 (pt) | 2021-10-26 |
JP2016532876A (ja) | 2016-10-20 |
MX2021008472A (es) | 2021-08-19 |
MX384530B (es) | 2025-03-14 |
KR20160049001A (ko) | 2016-05-04 |
CN111007236A (zh) | 2020-04-14 |
CN111007236B (zh) | 2022-01-14 |
US9302264B2 (en) | 2016-04-05 |
US20160243543A1 (en) | 2016-08-25 |
WO2015035256A3 (en) | 2015-07-16 |
US20200023353A1 (en) | 2020-01-23 |
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