CA2907417A1 - Microscope slides with quality controls thereon - Google Patents
Microscope slides with quality controls thereonInfo
- Publication number
- CA2907417A1 CA2907417A1 CA2907417A CA2907417A CA2907417A1 CA 2907417 A1 CA2907417 A1 CA 2907417A1 CA 2907417 A CA2907417 A CA 2907417A CA 2907417 A CA2907417 A CA 2907417A CA 2907417 A1 CA2907417 A1 CA 2907417A1
- Authority
- CA
- Canada
- Prior art keywords
- sample
- microscope slide
- control samples
- slide
- positive control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000003908 quality control method Methods 0.000 title 1
- 239000000523 sample Substances 0.000 claims abstract description 125
- 239000013641 positive control Substances 0.000 claims abstract description 95
- 238000010186 staining Methods 0.000 claims abstract description 80
- 239000000758 substrate Substances 0.000 claims abstract description 62
- 238000000034 method Methods 0.000 claims abstract description 37
- 238000004519 manufacturing process Methods 0.000 claims abstract description 4
- 239000008188 pellet Substances 0.000 claims description 57
- 239000000090 biomarker Substances 0.000 claims description 48
- 239000013068 control sample Substances 0.000 claims description 41
- 239000013642 negative control Substances 0.000 claims description 17
- 238000004458 analytical method Methods 0.000 claims description 15
- 239000000427 antigen Substances 0.000 claims description 12
- 102000036639 antigens Human genes 0.000 claims description 12
- 108091007433 antigens Proteins 0.000 claims description 12
- 238000001514 detection method Methods 0.000 claims description 12
- 239000003550 marker Substances 0.000 claims description 12
- 238000012790 confirmation Methods 0.000 claims description 6
- 239000012188 paraffin wax Substances 0.000 claims description 4
- 238000013179 statistical model Methods 0.000 claims description 4
- 239000012620 biological material Substances 0.000 claims description 2
- 238000004891 communication Methods 0.000 claims description 2
- 238000002508 contact lithography Methods 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 238000003709 image segmentation Methods 0.000 claims description 2
- 238000003018 immunoassay Methods 0.000 claims description 2
- 230000004807 localization Effects 0.000 claims description 2
- 230000000873 masking effect Effects 0.000 claims description 2
- 239000001993 wax Substances 0.000 claims description 2
- 239000013610 patient sample Substances 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 238000012744 immunostaining Methods 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 101150029707 ERBB2 gene Proteins 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 238000003364 immunohistochemistry Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000007170 pathology Effects 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000012192 staining solution Substances 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- -1 e.g. Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010166 immunofluorescence Methods 0.000 description 1
- 238000007901 in situ hybridization Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000000439 tumor marker Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00613—Quality control
- G01N35/00663—Quality control of consumables
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00613—Quality control
- G01N35/00663—Quality control of consumables
- G01N2035/00673—Quality control of consumables of reagents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Quality & Reliability (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Microscoopes, Condenser (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361806841P | 2013-03-30 | 2013-03-30 | |
| US61/806,841 | 2013-03-30 | ||
| PCT/US2014/031275 WO2014165327A1 (en) | 2013-03-30 | 2014-03-20 | Microscope slides with quality controls thereon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2907417A1 true CA2907417A1 (en) | 2014-10-09 |
Family
ID=51659130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2907417A Abandoned CA2907417A1 (en) | 2013-03-30 | 2014-03-20 | Microscope slides with quality controls thereon |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10082451B2 (enExample) |
| EP (1) | EP2979078B1 (enExample) |
| JP (1) | JP6540686B2 (enExample) |
| KR (1) | KR20150136599A (enExample) |
| CN (1) | CN105324654A (enExample) |
| AU (1) | AU2014248479B2 (enExample) |
| CA (1) | CA2907417A1 (enExample) |
| RU (1) | RU2015139001A (enExample) |
| SG (1) | SG11201508139UA (enExample) |
| WO (1) | WO2014165327A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6492897B2 (ja) * | 2015-04-02 | 2019-04-03 | コニカミノルタ株式会社 | 工程処理実施の有無を判別する手段を有するスライドグラス、組織切片スライド、組織切片用処理容器、および工程処理実施の有無の判別方法 |
| CN107923823A (zh) * | 2015-07-29 | 2018-04-17 | 奥林巴斯株式会社 | 标本染色系统 |
| EP3384271B1 (en) | 2015-12-03 | 2021-11-17 | Ventana Medical Systems, Inc. | Fluid coverage sensing system and method |
| JP2020098097A (ja) * | 2017-03-31 | 2020-06-25 | 松浪硝子工業株式会社 | スライドグラス及びスライドグラスの製造のための溶液 |
| JP7104907B2 (ja) * | 2017-04-28 | 2022-07-22 | 学校法人日本大学 | 組織切片選定方法 |
| KR102342993B1 (ko) * | 2017-06-15 | 2021-12-27 | 션전 피알에스 리미티드 | 면역 조직 화학적 착색을 위한 공정 기록 슬라이드 |
| CN110753846B (zh) * | 2017-06-15 | 2024-03-26 | 深圳市诺高实验器材有限公司 | 免疫组织化学抗原成像标尺外推方法 |
| US10921223B2 (en) | 2018-10-12 | 2021-02-16 | Shenzhen Prs Limited | Process record slide for staining and method of using the same |
| US11788043B2 (en) | 2018-12-21 | 2023-10-17 | Imoh S. Okon | Cell culture plate, assembly and methods of use |
| CN114207675A (zh) | 2019-05-28 | 2022-03-18 | 佩治人工智能公司 | 用于数字病理学的用于处理图像以针对所处理的图像制备载片的系统和方法 |
| FR3099581B1 (fr) * | 2019-07-29 | 2024-02-02 | Dreampath Diagnostics | Installation et procédé pour le contrôle de l’origine et/ou de la qualité de coupes d’échantillons biologiques |
| CN115605753A (zh) * | 2019-12-31 | 2023-01-13 | 深圳市诺高实验器材有限公司（Cn） | 用于疏松细胞的过程记录载玻片及其使用方法 |
| US20230160794A1 (en) * | 2021-11-24 | 2023-05-25 | 10X Genomics, Inc. | Methods for sample preparation for automated in situ analysis |
| CN116337555A (zh) * | 2021-12-22 | 2023-06-27 | 苏州图灵微生物科技有限公司 | 利用制样器制样进行形态学检测的方法 |
| JP2023152542A (ja) * | 2022-04-04 | 2023-10-17 | アークレイ株式会社 | コントロールキュベット |
| EP4467959A1 (en) * | 2023-05-26 | 2024-11-27 | Leica Microsystems CMS GmbH | Sample holder for a biological sample and method for analysing the biological sample |
| US12442729B2 (en) | 2023-11-13 | 2025-10-14 | Singular Genomics Systems, Inc. | Devices useful for sample manipulation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5078969A (en) * | 1989-12-14 | 1992-01-07 | Cell Analysis Systems, Inc. | Magnetic stirrer |
| JPH08145988A (ja) * | 1994-11-22 | 1996-06-07 | Chiyouki Hayashi | 異型リンパ球識別法 |
| US5958341A (en) | 1996-12-23 | 1999-09-28 | American Registry Of Pathology | Apparatus for efficient processing of tissue samples on slides |
| WO2000038838A1 (en) * | 1998-12-23 | 2000-07-06 | American Registry Of Pathology | Apparatus and methods for efficient processing of biological samples on slides |
| US7011940B1 (en) * | 1999-04-14 | 2006-03-14 | Medical Discovery Partners Llc | Quality control for cytochemical assays |
| EP1500963B1 (en) * | 2002-10-18 | 2008-05-21 | Hamamatsu Photonics K. K. | Slide glass, cover glass, and pathologic diagnosis system |
| GB0304515D0 (en) * | 2003-02-27 | 2003-04-02 | Dakocytomation Denmark As | Standard |
| JP2008541019A (ja) * | 2005-04-29 | 2008-11-20 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 組織学のための異種移植組織の対照 |
| US20100073766A1 (en) * | 2005-10-26 | 2010-03-25 | Angros Lee H | Microscope slide testing and identification assembly |
| WO2009085576A2 (en) | 2007-12-28 | 2009-07-09 | Spring Bioscience Corporation | Positive control cell pellets for immunohistochemistry and methods of use thereof |
| WO2011087894A1 (en) * | 2010-01-15 | 2011-07-21 | Qbc Diagnostics, Inc. | Fluorescent microscope slide |
| US20130044200A1 (en) | 2011-08-17 | 2013-02-21 | Datacolor, Inc. | System and apparatus for the calibration and management of color in microscope slides |
| US20130338014A1 (en) * | 2012-04-05 | 2013-12-19 | Vala Sciences, Inc. | Calibration Standards For Digital Histocytometry |
| WO2013179279A2 (en) * | 2012-05-28 | 2013-12-05 | Applied Spectral Imaging Ltd. | Method and device for analyzing biological sample |
-
2014
- 2014-03-20 RU RU2015139001A patent/RU2015139001A/ru unknown
- 2014-03-20 US US14/778,453 patent/US10082451B2/en active Active
- 2014-03-20 CA CA2907417A patent/CA2907417A1/en not_active Abandoned
- 2014-03-20 KR KR1020157026263A patent/KR20150136599A/ko not_active Withdrawn
- 2014-03-20 JP JP2016505501A patent/JP6540686B2/ja active Active
- 2014-03-20 EP EP14779365.7A patent/EP2979078B1/en active Active
- 2014-03-20 SG SG11201508139UA patent/SG11201508139UA/en unknown
- 2014-03-20 CN CN201480019175.5A patent/CN105324654A/zh active Pending
- 2014-03-20 AU AU2014248479A patent/AU2014248479B2/en not_active Ceased
- 2014-03-20 WO PCT/US2014/031275 patent/WO2014165327A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2979078A4 (en) | 2016-11-30 |
| CN105324654A (zh) | 2016-02-10 |
| JP6540686B2 (ja) | 2019-07-10 |
| US10082451B2 (en) | 2018-09-25 |
| AU2014248479B2 (en) | 2018-01-25 |
| EP2979078B1 (en) | 2020-05-20 |
| WO2014165327A1 (en) | 2014-10-09 |
| KR20150136599A (ko) | 2015-12-07 |
| AU2014248479A1 (en) | 2015-09-10 |
| US20160274008A1 (en) | 2016-09-22 |
| RU2015139001A (ru) | 2017-05-04 |
| EP2979078A1 (en) | 2016-02-03 |
| SG11201508139UA (en) | 2015-11-27 |
| JP2016520814A (ja) | 2016-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2014248479B2 (en) | Microscope slides with quality controls thereon | |
| US4790640A (en) | Laboratory slide | |
| CN110461244A (zh) | 用于处理、检测和多重分析完整固定的石蜡或塑料包埋（ifpe）的生物材料的多孔装置 | |
| US8597936B2 (en) | Device and method for the automated and reproducible production of cell or tissue samples that are to be analyzed and are arranged on object supports | |
| EP1883823B1 (en) | Dispensing of a diagnostic liquid onto a diagnostic reagent | |
| US20150211964A1 (en) | Method and analysis device for microscopic examination of a tissue section or cell smear | |
| US10024842B2 (en) | Methods and devices for quantitating blood samples | |
| EP3253284B1 (en) | Liquid volumetric measurement device | |
| US20130090253A1 (en) | Accurate quantitation of biomarkers in samples | |
| EP2269028A2 (de) | Automatische vorrichtung zur durchführung von nachweisreaktionen und verfahren zur dosierung von reagenzien auf objektträgern | |
| CA2432934A1 (en) | Substrate for microarray | |
| US7883667B2 (en) | Methods and apparatus for efficiently using fluids in a slide stainer | |
| EP1101143A1 (en) | Slides with reaction zones defined by hydrophobic barriers | |
| Hermann et al. | Rapid mass spectrometric calibration and standard addition using hydrophobic/hydrophilic patterned surfaces and discontinuous dewetting | |
| US12313834B2 (en) | Paraffin shield coating for microscope slide | |
| CN118329583B (zh) | 一种用于制备多样本单细胞悬液玻片微阵列的装置 | |
| US20240230636A1 (en) | Assay cartridge and manufacturing method of assay strip | |
| US20210011043A1 (en) | Reagent deposition verification | |
| WO2001046671A1 (en) | Apparatus and method for image analysis quality control and assurance | |
| CA3005214A1 (en) | A diagnostic strip for determining the amount of sarcosine, creatinine and hydrogen peroxide in a biological or environmental sample | |
| CN109647552B (zh) | 集成式的微阵列生物芯片及识别方法 | |
| US20230127232A1 (en) | Flow assay cartridge | |
| WO2025231532A1 (en) | Lateral flow printing, test, and detection method | |
| JPH09318625A (ja) | 多項目尿試験紙 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20180320 |