CA2899350C - Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies - Google Patents

Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies Download PDF

Info

Publication number
CA2899350C
CA2899350C CA2899350A CA2899350A CA2899350C CA 2899350 C CA2899350 C CA 2899350C CA 2899350 A CA2899350 A CA 2899350A CA 2899350 A CA2899350 A CA 2899350A CA 2899350 C CA2899350 C CA 2899350C
Authority
CA
Canada
Prior art keywords
lbd
vdr
vitamin
antibody
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2899350A
Other languages
English (en)
French (fr)
Other versions
CA2899350A1 (en
Inventor
Joshua Soldo
Gregory Olson
Michael Lutterman
John Wall
Michael New
Hector Floyd Deluca
Fabrizio Bonelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diasorin Italia SpA
Original Assignee
Diasorin Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47598742&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2899350(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Diasorin Italia SpA filed Critical Diasorin Italia SpA
Publication of CA2899350A1 publication Critical patent/CA2899350A1/en
Application granted granted Critical
Publication of CA2899350C publication Critical patent/CA2899350C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2899350A 2013-01-28 2014-01-27 Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies Active CA2899350C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13152851.5 2013-01-28
EP13152851.5A EP2759550B1 (en) 2013-01-28 2013-01-28 Method and kit for detecting 1,25-dihydroxyvitamin D and related antibodies
PCT/EP2014/051482 WO2014114780A1 (en) 2013-01-28 2014-01-27 Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies

Publications (2)

Publication Number Publication Date
CA2899350A1 CA2899350A1 (en) 2014-07-31
CA2899350C true CA2899350C (en) 2023-01-10

Family

ID=47598742

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2899350A Active CA2899350C (en) 2013-01-28 2014-01-27 Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies

Country Status (13)

Country Link
US (2) US10196449B2 (enExample)
EP (3) EP2759550B1 (enExample)
JP (1) JP6471099B2 (enExample)
KR (1) KR102196924B1 (enExample)
CN (1) CN104955841B (enExample)
AU (1) AU2014209857B2 (enExample)
CA (1) CA2899350C (enExample)
DK (2) DK2759550T3 (enExample)
ES (2) ES2696075T3 (enExample)
PL (2) PL2759550T3 (enExample)
PT (2) PT2759550T (enExample)
WO (1) WO2014114780A1 (enExample)
ZA (1) ZA201505263B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11261257B2 (en) 2013-01-28 2022-03-01 Diasorin S.P.A. Methods for detecting 1,25-dihydroxyvitamin D and related antibodies
EP2759550B1 (en) 2013-01-28 2018-08-15 DiaSorin S.p.A. Method and kit for detecting 1,25-dihydroxyvitamin D and related antibodies
US10983136B2 (en) 2013-01-28 2021-04-20 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker
CN104502599B (zh) * 2014-12-19 2016-08-24 同昕生物技术（北京）有限公司 25-羟基维生素d定量检测试纸条及其应用
AU2016207734A1 (en) * 2015-01-18 2017-08-03 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker
WO2017127833A1 (en) * 2016-01-22 2017-07-27 Affimedix, Inc. Device for detection of vitamin d metabolites
US10247728B1 (en) 2016-03-17 2019-04-02 Charm Sciences, Inc. Method and assay for detection of residues
EP3401681B1 (en) 2017-05-11 2023-03-29 Boditech Med Inc. Method for quick quantification assay of vitamin d based on fluorescence measurement using lateral flow cartridge
CN108362688B (zh) * 2018-01-02 2021-08-24 北京利德曼生化股份有限公司 一种25羟基维生素d磁微粒化学发光检测试剂盒
JP7434144B2 (ja) * 2018-02-27 2024-02-20 株式会社島津製作所 ＡＰＰ６６９－ｘのＮ末端を特異的に認識する抗体、及び免疫測定法
EP3829734A4 (en) * 2018-07-27 2022-06-15 Veravas, Inc. METHODS OF DEPLETION AND ENRICHMENT
CN109601477A (zh) * 2018-12-21 2019-04-12 云南农业大学 一种基于维生素d受体血液生化标记选育武定鸡的方法
CN110058028B (zh) * 2019-05-05 2021-03-02 苏州长光华医生物医学工程有限公司 一种24,25-双羟基维生素d免疫检测试剂盒及其应用
CN113999311B (zh) * 2020-07-28 2022-11-04 东莞市朋志生物科技有限公司 可特异性结合25-羟基维生素d的抗体、其应用以及诊断试剂盒
CN113884687B (zh) * 2021-12-08 2022-02-11 南京岚轩生物科技有限公司 用于检测25-羟基维生素d含量的解离剂及其制备方法
CN119080938B (zh) * 2023-06-05 2025-06-24 东莞市朋志生物科技有限公司 抗25羟维生素d抗体、检测25羟维生素d的试剂和试剂盒
CN119827779A (zh) * 2023-10-12 2025-04-15 菲鹏生物股份有限公司 维生素d均相检测方法和试剂
CN119846237B (zh) * 2024-11-22 2025-10-31 厦门康基生物科技有限公司 一种基于VDR和RXRα双夹心检测25-OH-VD的方法
CN119322137A (zh) * 2024-12-17 2025-01-17 凯莱谱科技股份有限公司 血清维生素d代谢通路代谢物的液相色谱串联质谱检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8408193D0 (en) * 1984-03-30 1984-05-10 Cambridge Patent Dev Antibodies
US4816417A (en) 1987-08-14 1989-03-28 Wisconsin Alumni Research Foundation Assay for 1,25-dihydroxy vitamin D in sample containing vitamin D transport protein
US5260199A (en) * 1991-07-30 1993-11-09 Wisconsin Alumni Research Foundation Method of producing 1,25-dihydroxyvitamin D3 receptor protein
JPH06109727A (ja) * 1992-08-14 1994-04-22 Wisconsin Alumni Res Found １，２５−ジヒドロキシビタミンｄの検定法
KR940009957A (ko) * 1992-10-09 1994-05-24 정명식 높은 보자력을 갖는 코발트/파라디움 광자기 다층박막 및 그 제조방법
JPH07330800A (ja) * 1994-06-08 1995-12-19 Yamasa Shoyu Co Ltd ビタミンｄ受容体に対するモノクローナル抗体
US6516294B1 (en) 1999-07-01 2003-02-04 The Regents Of The University Of California Nuclear receptor for 1α,25-dihydroxyvitamin D3 useful for selection of vitamin D3 ligands and a method therefor
DK2126586T3 (da) * 2007-02-01 2010-10-11 Immundiagnostik Ag Direkte bestemmelse af vitamin D i serum eller plasma
ES2593356T3 (es) * 2008-04-02 2016-12-07 Opko Ireland Global Holdings, Ltd. Métodos, composiciones, usos y kits útiles para la deficiencia de la vitamina D y trastornos relacionados
GB0903469D0 (en) * 2009-03-02 2009-04-08 Axis Shield Diagnostics Ltd Assay
WO2010128393A1 (en) 2009-05-06 2010-11-11 Cytochroma Inc. Method and composition for measuring the amount of vitamin d derivatives
EP2457916A1 (en) * 2010-11-16 2012-05-30 DiaSorin S.p.A. Compound for the covalent attachment of the chemiluminescent probe N-(4-Aminobutyl)-N-ethylisoluminol (ABEI) to target molecules and uses thereof
GB201101801D0 (en) * 2011-02-02 2011-03-16 Axis Shield Diagnostics Ltd Binding molecule and method for measuring
AU2012312907A1 (en) 2011-08-26 2014-03-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2759551B1 (en) 2011-09-21 2019-05-22 Fujirebio Inc. Antibodies binding to an affinity complex comprising 25oh vitamin d2 or d3 and an antibody thereto
US10983136B2 (en) * 2013-01-28 2021-04-20 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker
EP2759550B1 (en) 2013-01-28 2018-08-15 DiaSorin S.p.A. Method and kit for detecting 1,25-dihydroxyvitamin D and related antibodies

Also Published As

Publication number Publication date
AU2014209857A1 (en) 2015-08-13
PT2759550T (pt) 2018-11-16
DK2759550T3 (en) 2018-11-26
ZA201505263B (en) 2016-06-29
CN104955841B (zh) 2018-05-04
EP2759550B1 (en) 2018-08-15
JP2016505634A (ja) 2016-02-25
WO2014114780A1 (en) 2014-07-31
ES2780823T3 (es) 2020-08-27
US20150361178A1 (en) 2015-12-17
KR102196924B1 (ko) 2020-12-31
DK2948474T3 (da) 2020-03-09
HK1218129A1 (en) 2017-02-03
PT2948474T (pt) 2020-03-05
EP2759550A1 (en) 2014-07-30
EP3650467A1 (en) 2020-05-13
CN104955841A (zh) 2015-09-30
KR20150110680A (ko) 2015-10-02
PL2948474T3 (pl) 2020-07-27
JP6471099B2 (ja) 2019-02-13
CA2899350A1 (en) 2014-07-31
AU2014209857B2 (en) 2018-10-04
EP2948474A1 (en) 2015-12-02
PL2759550T3 (pl) 2019-01-31
US10501548B2 (en) 2019-12-10
ES2696075T3 (es) 2019-01-14
US10196449B2 (en) 2019-02-05
EP2948474B1 (en) 2020-01-15
US20170267770A1 (en) 2017-09-21

Similar Documents

Publication Publication Date Title
CA2899350C (en) Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies
RU2657517C2 (ru) Анализ адромедуллина и способы определения зрелого адромедуллина
KR102425339B1 (ko) 비타민 d 의 측정을 위한 방법
US20210072264A1 (en) Use of 1,25-Dihydroxyvitamin D Values in Ratio with PTH as a Prognostic Biomarker
US10421812B2 (en) Isoform specific soluble FMS-like tyrosine kinase (sFlt) binding agents and uses thereof
US11261257B2 (en) Methods for detecting 1,25-dihydroxyvitamin D and related antibodies
WO2025027012A1 (en) Assay for mybpc3
EP4551607A1 (en) Assay for mybpc3
CN110352351B (zh) 使用抗人bnp片段(4-32)抗体的免疫测定方法
HK1218129B (en) Method and kit for detecting 1,25-dihydroxyvitamin d and related antibodies
JP2014091719A (ja) ヒトｂ型ナトリウム利尿ペプチドの３−３２位に相当するポリペプチドに対する特異抗体およびそれを用いた測定法
JP2014028770A (ja) ヒトｂ型ナトリウム利尿ペプチド特異抗体およびそれを用いた測定法
CN114286826A (zh) 检测人α防御素HD5的方法和试剂盒、以及其中所使用的抗体
BR112017008985B1 (pt) Método in vitro para a determinação da concentração de 25-hidroxivitamina d, uso de um método in vitro, uso de um primeiro agente de ligação e kit
JP2015137272A (ja) 新規のペプチド及び疾患の検出方法

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190115

EEER Examination request

Effective date: 20190115

EEER Examination request

Effective date: 20190115

EEER Examination request

Effective date: 20190115