CA2899010A1 - Spiro-lactam nmda receptor modulators and uses thereof - Google Patents
Spiro-lactam nmda receptor modulators and uses thereof Download PDFInfo
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- CA2899010A1 CA2899010A1 CA2899010A CA2899010A CA2899010A1 CA 2899010 A1 CA2899010 A1 CA 2899010A1 CA 2899010 A CA2899010 A CA 2899010A CA 2899010 A CA2899010 A CA 2899010A CA 2899010 A1 CA2899010 A1 CA 2899010A1
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- Prior art keywords
- compound
- alkyl
- group
- halogen
- methyl
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Classifications
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Organic Chemistry (AREA)
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- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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- Physiology (AREA)
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| KR102462288B1 (ko) * | 2016-08-01 | 2022-11-01 | 앱티닉스 인크. | 스피로-락탐 및 비스-스피로-락탐 nmda 수용체 조정제 및 그의 용도 |
| JP2019527233A (ja) * | 2016-08-01 | 2019-09-26 | アプティニックス インコーポレイテッド | スピロ−ラクタムｎｍｄａ受容体修飾因子及びその使用 |
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2014
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- 2014-01-29 AU AU2014212490A patent/AU2014212490A1/en not_active Abandoned
- 2014-01-29 PE PE2015001565A patent/PE20151438A1/es not_active Application Discontinuation
- 2014-01-29 WO PCT/US2014/013626 patent/WO2014120789A1/en not_active Ceased
- 2014-01-29 SG SG11201505937SA patent/SG11201505937SA/en unknown
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- 2014-01-29 MX MX2015009778A patent/MX2015009778A/es unknown
- 2014-01-29 EA EA201591404A patent/EA201591404A1/ru unknown
- 2014-01-29 KR KR1020157021534A patent/KR20150110586A/ko not_active Withdrawn
- 2014-01-29 CN CN201480006688.2A patent/CN105026401A/zh active Pending
- 2014-01-29 BR BR112015018095A patent/BR112015018095A2/pt not_active IP Right Cessation
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- 2015-07-29 CL CL2015002124A patent/CL2015002124A1/es unknown
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2017
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| CN105026401A (zh) | 2015-11-04 |
| EP2951186B1 (en) | 2018-07-25 |
| AU2014212490A1 (en) | 2015-07-30 |
| BR112015018095A2 (pt) | 2017-07-18 |
| JP2016506961A (ja) | 2016-03-07 |
| PH12015501600A1 (en) | 2015-10-19 |
| EP2951186A1 (en) | 2015-12-09 |
| KR20150110586A (ko) | 2015-10-02 |
| WO2014120789A1 (en) | 2014-08-07 |
| EA201591404A1 (ru) | 2016-01-29 |
| US20180155354A1 (en) | 2018-06-07 |
| CL2015002124A1 (es) | 2015-12-04 |
| SG11201505937SA (en) | 2015-09-29 |
| US9738650B2 (en) | 2017-08-22 |
| US10253032B2 (en) | 2019-04-09 |
| PE20151438A1 (es) | 2015-10-10 |
| IL240165A0 (en) | 2015-09-24 |
| US20150376195A1 (en) | 2015-12-31 |
| MX2015009778A (es) | 2016-02-09 |
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