PT2485751E - Glyx-13 para uso num método para tratar depressão refratária - Google Patents

Glyx-13 para uso num método para tratar depressão refratária Download PDF

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Publication number
PT2485751E
PT2485751E PT108225145T PT10822514T PT2485751E PT 2485751 E PT2485751 E PT 2485751E PT 108225145 T PT108225145 T PT 108225145T PT 10822514 T PT10822514 T PT 10822514T PT 2485751 E PT2485751 E PT 2485751E
Authority
PT
Portugal
Prior art keywords
glyx
refractory depression
treating refractory
treating
depression
Prior art date
Application number
PT108225145T
Other languages
English (en)
Inventor
Joseph Moskal
Original Assignee
Univ Northwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern filed Critical Univ Northwestern
Publication of PT2485751E publication Critical patent/PT2485751E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
PT108225145T 2009-10-05 2010-10-05 Glyx-13 para uso num método para tratar depressão refratária PT2485751E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24865009P 2009-10-05 2009-10-05

Publications (1)

Publication Number Publication Date
PT2485751E true PT2485751E (pt) 2014-09-01

Family

ID=43857351

Family Applications (2)

Application Number Title Priority Date Filing Date
PT15171991T PT2985032T (pt) 2009-10-05 2010-10-05 Glyx para utilização no tratamento da doença de alzheimer, doença de parkinson ou doença de huntington
PT108225145T PT2485751E (pt) 2009-10-05 2010-10-05 Glyx-13 para uso num método para tratar depressão refratária

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT15171991T PT2985032T (pt) 2009-10-05 2010-10-05 Glyx para utilização no tratamento da doença de alzheimer, doença de parkinson ou doença de huntington

Country Status (12)

Country Link
EP (4) EP3488856A1 (pt)
CY (1) CY1118530T1 (pt)
DK (2) DK2985032T3 (pt)
ES (2) ES2493316T3 (pt)
HR (1) HRP20140784T1 (pt)
HU (1) HUE043807T2 (pt)
PL (2) PL2485751T3 (pt)
PT (2) PT2985032T (pt)
RS (1) RS53513B1 (pt)
SI (1) SI2485751T1 (pt)
SM (1) SMT201400117B (pt)
WO (1) WO2011044089A2 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101769999B1 (ko) 2008-09-18 2017-08-21 노오쓰웨스턴 유니버시티 Ｎｍｄａ 수용체 조절제 및 그의 용도
US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
KR101692275B1 (ko) * 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 ２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도
JP5928828B2 (ja) 2010-02-11 2016-06-01 ノースウエスタン ユニバーシティ Ｎｍｄａ受容体モジュレータを安定化させる二次構造及びその使用
US10583138B2 (en) 2012-07-12 2020-03-10 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
BR112013027554A2 (pt) * 2011-04-27 2016-09-06 Univ Northwestern "usos de compostos no tratamento de mal de alzheimer, doença de huntington, autismo e outros distúrbios"
AU2013329000A1 (en) * 2012-10-12 2015-04-30 Northwestern University Methods of identifying compounds for treating depression and other related diseases
CN105408336B (zh) 2013-01-29 2018-06-26 阿普廷伊克斯股份有限公司 螺-内酰胺nmda受体调节剂及其用途
JP2016506958A (ja) 2013-01-29 2016-03-07 ノーレックス, インコーポレイテッドNaurex, Inc. スピロラクタム系ｎｍｄａ受容体モジュレーターおよびその使用
SG11201505934XA (en) 2013-01-29 2015-09-29 Naurex Inc Spiro-lactam nmda receptor modulators and uses thereof
JP2016506962A (ja) 2013-01-29 2016-03-07 ノーレックス, インコーポレイテッドNaurex, Inc. スピロラクタム系ｎｍｄａ受容体モジュレーターおよびその使用
PE20151438A1 (es) 2013-01-29 2015-10-10 Naurex Inc Moduladores de receptores nmda de espiro-lactama y sus usos
CN106102762A (zh) * 2013-12-13 2016-11-09 西北大学 治疗脑部病症或鉴定与其相关的生物标记的方法
CN105327349A (zh) * 2014-06-18 2016-02-17 上海翰森生物医药科技有限公司 Nmda受体拮抗剂的医药用途及其药物组合物
WO2015200322A1 (en) * 2014-06-23 2015-12-30 Northwestern University Methods of treating or ameliorating migraine
BR112017002930A2 (pt) * 2014-08-14 2017-12-05 Naurex Inc ?métodos de tratamento de depressão usando moduladores de nmda?
AU2016340080A1 (en) * 2015-10-16 2018-05-10 Northwestern University Pharmaceutical combination of an atypical antipsychotic and an NMDA modulator for the treatment of schizophrenia,bipolar disorder, cognitive impairment and major depressive disorder
US10591461B2 (en) 2016-04-28 2020-03-17 The Trustees Of The University Of Pennsylvania Method of drug design and optimisation utilizing stereochemical mimicry
WO2017201285A1 (en) 2016-05-19 2017-11-23 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
EA201892657A1 (ru) 2016-05-19 2019-05-31 Аптиникс Инк. Спиролактамовые модуляторы nmda-рецептора и их применение
MX2019001318A (es) 2016-08-01 2019-07-01 Aptinyx Inc Moduladores del receptor nmda espiro-lactam y uso de los mismos.
US11299495B2 (en) 2016-08-01 2022-04-12 Aptinyx Inc. Spiro-lactam NMDA receptor modulators and uses thereof
PE20190502A1 (es) 2016-08-01 2019-04-10 Aptinyx Inc Moduladores del receptor nmda spiro-lactam y bis-spiro-lactam y uso de los mismos
CN109890825B (zh) 2016-08-01 2022-03-11 阿普廷伊克斯股份有限公司 螺-内酰胺nmda受体调节剂及其用途
CA3031563C (en) 2016-08-01 2023-12-05 Aptinyx Inc. Spiro-lactam nmda modulators and methods of using same
JP7210599B2 (ja) 2018-01-31 2023-01-23 アプティニックス インコーポレイテッド スピロラクタム系ｎｍｄａ受容体修飾因子およびその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US5763393A (en) 1996-05-17 1998-06-09 Neurotherapeutics L.P. Neuroactive peptides
WO2002072005A2 (en) * 2001-03-07 2002-09-19 University Of Utah Research Foundation Linear y-carboxyglutamate rich conotoxins
AU2002255705A1 (en) * 2001-03-12 2002-09-24 Nyxis Neurotherapies, Inc Neuroactive peptides for prevention and/or treatment of hypoxia and neuropathic pain
EP1660634A4 (en) * 2003-08-08 2009-02-18 Burnham Inst P16-mediated regulation of NMDA receptors
US20050096311A1 (en) * 2003-10-30 2005-05-05 Cns Response Compositions and methods for treatment of nervous system disorders

Also Published As

Publication number Publication date
PL2985032T3 (pl) 2019-07-31
EP3488856A1 (en) 2019-05-29
EP2485751A4 (en) 2013-03-13
SI2485751T1 (sl) 2014-10-30
WO2011044089A2 (en) 2011-04-14
PL2485751T3 (pl) 2014-10-31
ES2721448T3 (es) 2019-07-31
EP2985032A1 (en) 2016-02-17
DK2985032T3 (en) 2019-04-15
EP2485751B1 (en) 2014-05-21
PT2985032T (pt) 2019-04-24
CY1118530T1 (el) 2017-07-12
HUE043807T2 (hu) 2019-09-30
EP2985032B1 (en) 2019-01-02
RS53513B1 (en) 2015-02-27
ES2493316T3 (es) 2014-09-11
WO2011044089A3 (en) 2012-02-16
EP2485751A2 (en) 2012-08-15
SMT201400117B (it) 2014-11-10
HRP20140784T1 (hr) 2014-10-10
DK2485751T3 (da) 2014-08-18
EP2813236A1 (en) 2014-12-17

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