ES2493316T3 - GLYX-13 para uso en un método para tratar depresión que no responde al tratamiento - Google Patents

GLYX-13 para uso en un método para tratar depresión que no responde al tratamiento Download PDF

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Publication number
ES2493316T3
ES2493316T3 ES10822514.5T ES10822514T ES2493316T3 ES 2493316 T3 ES2493316 T3 ES 2493316T3 ES 10822514 T ES10822514 T ES 10822514T ES 2493316 T3 ES2493316 T3 ES 2493316T3
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Spain
Prior art keywords
glyx
treatment
respond
treat depression
patient
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Active
Application number
ES10822514.5T
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English (en)
Inventor
Joseph Moskal
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Northwestern University
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Northwestern University
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Publication date
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Ceramic Products (AREA)
  • Glass Compositions (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

GLYX-13 para uso en un método para tratar depresión que no responde al tratamiento en un paciente resistente al tratamiento que lo necesita, en el que GLYX-13 debe administrarse a dicho paciente, mediante lo cual se alivia sustancialmente al menos un síntoma en dicho paciente en el plazo de aproximadamente 14 días.

Description

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Claims (1)

  1. imagen1
ES10822514.5T 2009-10-05 2010-10-05 GLYX-13 para uso en un método para tratar depresión que no responde al tratamiento Active ES2493316T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24865009P 2009-10-05 2009-10-05
US248650P 2009-10-05
PCT/US2010/051415 WO2011044089A2 (en) 2009-10-05 2010-10-05 Methods of treating depression and other related diseases

Publications (1)

Publication Number Publication Date
ES2493316T3 true ES2493316T3 (es) 2014-09-11

Family

ID=43857351

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10822514.5T Active ES2493316T3 (es) 2009-10-05 2010-10-05 GLYX-13 para uso en un método para tratar depresión que no responde al tratamiento
ES15171991T Active ES2721448T3 (es) 2009-10-05 2010-10-05 GLYX-13 para uso en el tratamiento de enfermedad de Alzheimer, enfermedad de Parkinson y enfermedad de Huntington

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES15171991T Active ES2721448T3 (es) 2009-10-05 2010-10-05 GLYX-13 para uso en el tratamiento de enfermedad de Alzheimer, enfermedad de Parkinson y enfermedad de Huntington

Country Status (12)

Country Link
EP (4) EP3488856A1 (es)
CY (1) CY1118530T1 (es)
DK (2) DK2985032T3 (es)
ES (2) ES2493316T3 (es)
HR (1) HRP20140784T1 (es)
HU (1) HUE043807T2 (es)
PL (2) PL2985032T3 (es)
PT (2) PT2985032T (es)
RS (1) RS53513B1 (es)
SI (1) SI2485751T1 (es)
SM (1) SMT201400117B (es)
WO (1) WO2011044089A2 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5702288B2 (ja) 2008-09-18 2015-04-15 ノースウエスタン ユニバーシティ Ｎｍｄａレセプターモジュレータ及びその用途
US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
BR112012020142A2 (pt) 2010-02-11 2020-08-18 Northwestern University moduladores do receptor de nmda com estrutura secundária estabilizada e usos dos mesmos.
KR101692275B1 (ko) * 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 ２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
US10583138B2 (en) 2012-07-12 2020-03-10 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
SG10202010665YA (en) * 2011-04-27 2020-11-27 Univ Northwestern Methods of treating alzheimer's disease, huntington's disease, autism, or other disorders
CA2887875A1 (en) * 2012-10-12 2014-04-17 Northwestern University Methods of identifying compounds for treating depression and other related diseases
WO2014120789A1 (en) 2013-01-29 2014-08-07 Naurex, Inc. Spiro-lactam nmda receptor modulators and uses thereof
LT3514158T (lt) 2013-01-29 2023-02-10 Aptinyx Inc. Spirolaktaminiai nmda receptoriaus moduliatoriai ir jų panaudojimas
SG11201505934XA (en) 2013-01-29 2015-09-29 Naurex Inc Spiro-lactam nmda receptor modulators and uses thereof
CA2899191A1 (en) 2013-01-29 2014-08-07 Naurex, Inc. Spiro-lactam nmda receptor modulators and uses thereof
WO2014120784A1 (en) 2013-01-29 2014-08-07 Naurex, Inc. Spiro-lactam nmda receptor modulators and uses thereof
EP3079579A4 (en) * 2013-12-13 2017-07-19 Northwestern University Treating brain disorders and biomarkers related thereto
CN105327349A (zh) * 2014-06-18 2016-02-17 上海翰森生物医药科技有限公司 Nmda受体拮抗剂的医药用途及其药物组合物
EP3157943A4 (en) * 2014-06-23 2018-01-24 Northwestern University Methods of treating or ameliorating migraine
CA2957937A1 (en) * 2014-08-14 2016-02-18 Naurex, Inc. Methods of treating depression using nmda modulators
US20180325893A1 (en) * 2015-10-16 2018-11-15 Northwestern University Subacute administration of nmda modulators alone or in combination
WO2017189920A1 (en) * 2016-04-28 2017-11-02 The Trustees Of The University Of Pennsylvania Method of drug design and optimisation utilizing stereochemical mimicry
PE20190174A1 (es) 2016-05-19 2019-02-01 Aptinyx Inc Moduladores del receptor espiro-lactama n-metil-d-aspartato y usos de los mismos
WO2017201285A1 (en) 2016-05-19 2017-11-23 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
EP3490994B8 (en) 2016-08-01 2024-03-13 Tenacia Biotechnology (Hong Kong) Co., Limited Spiro-lactam and bis-spiro-lactam nmda receptor modulators and uses thereof
IL286107B1 (en) 2016-08-01 2024-05-01 Aptinyx Inc Spiro-lactam NMDA receptor modulators and their uses
BR112019001921A2 (pt) 2016-08-01 2019-05-14 Aptinyx Inc. moduladores do receptor nmda de espiro-lactama e seus usos
IL264482B (en) 2016-08-01 2022-09-01 Aptinyx Inc Spiro-lactam nmda modulators and methods of their use
MX2019001319A (es) 2016-08-01 2019-07-04 Aptinyx Inc Moduladores del receptor nmda espiro-lactam y uso de los mismos.
KR20200115611A (ko) 2018-01-31 2020-10-07 앱티닉스 인크. 스피로-락탐 nmda 수용체 조정제 및 그의 용도
US12012413B2 (en) 2019-11-11 2024-06-18 Tenacia Biotechnology (Hong Kong) Co., Limited Methods of treating painful diabetic peripheral neuropathy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
US5763393A (en) 1996-05-17 1998-06-09 Neurotherapeutics L.P. Neuroactive peptides
WO2002072005A2 (en) * 2001-03-07 2002-09-19 University Of Utah Research Foundation Linear y-carboxyglutamate rich conotoxins
WO2002072609A2 (en) * 2001-03-12 2002-09-19 Nyxis Neurotherapies, Inc Neuroactive peptides for prevention and/or treatment of hypoxia and neuropathic pain
CA2534909A1 (en) * 2003-08-08 2005-02-17 The Burnham Institute P16 mediated regulation of nmda receptors
US20050096311A1 (en) * 2003-10-30 2005-05-05 Cns Response Compositions and methods for treatment of nervous system disorders

Also Published As

Publication number Publication date
EP2813236A1 (en) 2014-12-17
PT2485751E (pt) 2014-09-01
DK2485751T3 (da) 2014-08-18
CY1118530T1 (el) 2017-07-12
HRP20140784T1 (hr) 2014-10-10
RS53513B1 (en) 2015-02-27
SMT201400117B (it) 2014-11-10
WO2011044089A2 (en) 2011-04-14
EP3488856A1 (en) 2019-05-29
SI2485751T1 (sl) 2014-10-30
EP2485751B1 (en) 2014-05-21
DK2985032T3 (en) 2019-04-15
EP2985032B1 (en) 2019-01-02
WO2011044089A3 (en) 2012-02-16
EP2485751A2 (en) 2012-08-15
PL2485751T3 (pl) 2014-10-31
ES2721448T3 (es) 2019-07-31
EP2985032A1 (en) 2016-02-17
HUE043807T2 (hu) 2019-09-30
EP2485751A4 (en) 2013-03-13
PL2985032T3 (pl) 2019-07-31
PT2985032T (pt) 2019-04-24

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