CA2888982C - Platelet targeted treatment - Google Patents
Platelet targeted treatment Download PDFInfo
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- CA2888982C CA2888982C CA2888982A CA2888982A CA2888982C CA 2888982 C CA2888982 C CA 2888982C CA 2888982 A CA2888982 A CA 2888982A CA 2888982 A CA2888982 A CA 2888982A CA 2888982 C CA2888982 C CA 2888982C
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C07K14/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201261717951P | 2012-10-24 | 2012-10-24 | |
| US61/717,951 | 2012-10-24 | ||
| PCT/US2013/066651 WO2014066663A1 (en) | 2012-10-24 | 2013-10-24 | Platelet targeted treatment |
Publications (2)
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| CA2888982A1 CA2888982A1 (en) | 2014-05-01 |
| CA2888982C true CA2888982C (en) | 2020-07-21 |
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| CA2888982A Active CA2888982C (en) | 2012-10-24 | 2013-10-24 | Platelet targeted treatment |
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| EP (2) | EP3859004A1 (OSRAM) |
| JP (2) | JP2016501515A (OSRAM) |
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| PL (1) | PL2912186T3 (OSRAM) |
| WO (1) | WO2014066663A1 (OSRAM) |
| ZA (1) | ZA201502945B (OSRAM) |
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| WO2017011550A1 (en) | 2015-07-13 | 2017-01-19 | University Of Utah Research Foundation | Methods of making red blood cells and platelets in vitro and uses thereof |
| US20200291356A1 (en) * | 2019-03-13 | 2020-09-17 | Cellphire, Inc. | Canine blood platelet preparations |
| BR112020013656A2 (pt) | 2018-01-05 | 2020-12-01 | Platelet Biogenesis, Inc. | composições e métodos para produção de megacariócitos |
| CA3105205A1 (en) | 2018-06-29 | 2020-01-02 | Platelet Biogenesis, Inc. | Compositions for drug delivery and methods of use thereof |
| CA3115104A1 (en) * | 2018-10-05 | 2020-04-09 | University Of Utah Research Foundation | Methods of making platelets comprising modified receptors and uses thereof |
| US11767511B2 (en) | 2018-11-30 | 2023-09-26 | Cellphire, Inc. | Platelets as delivery agents |
| CA3121484A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets loaded with anti-cancer agents |
| CN114072159A (zh) | 2019-05-03 | 2022-02-18 | 塞尔菲乐有限公司 | 用于生产血液产品的材料和方法 |
| EP4013496A4 (en) | 2019-08-16 | 2023-10-18 | Cellphire Inc. | THROMBOSOMES AS AN AGENT FOR REMOVING THE THROMBOCYTE AGGREGATION-INHIBITING EFFECT |
| WO2021158645A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Methods of treating congenital hemophilia with anti-fibrinolytic loaded platelets |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| US20220273724A1 (en) | 2021-02-17 | 2022-09-01 | Cellphire Inc. | Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy |
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| US2452892A (en) | 1947-05-07 | 1948-11-02 | Robert A Appleton | Igniter for rockets |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| EP0468520A3 (en) | 1990-07-27 | 1992-07-01 | Mitsui Toatsu Chemicals, Inc. | Immunostimulatory remedies containing palindromic dna sequences |
| IL101715A (en) | 1991-05-02 | 2005-06-19 | Amgen Inc | Recombinant dna-derived cholera toxin subunit analogs |
| IT1253009B (it) | 1991-12-31 | 1995-07-10 | Sclavo Ricerca S R L | Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini |
| CA2138997C (en) | 1992-06-25 | 2003-06-03 | Jean-Paul Prieels | Vaccine composition containing adjuvants |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| DK0772619T4 (da) | 1994-07-15 | 2011-02-21 | Univ Iowa Res Found | Immunmodulatoriske oligonukleotider |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| ATE234129T1 (de) | 1996-06-18 | 2003-03-15 | Alza Corp | Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| JP4153999B2 (ja) | 1996-12-20 | 2008-09-24 | アルザ・コーポレーション | 経皮作用剤流量を強化するための組成物と方法 |
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| NZ504894A (en) | 1997-12-02 | 2002-12-20 | Powderject Vaccines Inc | Crystalline vaccine and adjuvant compositions jointly and separately administered to animals using a transdermal or transmucosally delivery technique |
| EP1048736A1 (en) * | 1999-04-27 | 2000-11-02 | Aventis Behring Gesellschaft mit beschränkter Haftung | DNA-construct for the tissue specific expression of a blood coagulation factor |
| US20040192599A1 (en) * | 2001-06-15 | 2004-09-30 | Schuh Andre C | Gene therapy for hemophilia a |
| EP1412493B1 (en) | 2001-08-02 | 2011-10-05 | Institut Clayton De La Recherche | Methods and compositions relating to improved lentiviral vector production systems |
| US20050238660A1 (en) | 2001-10-06 | 2005-10-27 | Babiuk Lorne A | Cpg formulations and related methods |
| WO2005017160A2 (en) | 2003-08-13 | 2005-02-24 | Children's Hospital Medical Center | Mobilization of hematopoietic cells |
| AU2005300688B2 (en) | 2004-11-03 | 2012-02-02 | Almac Diagnostics Limited | Transcriptome microarray technology and methods of using the same |
| KR100981092B1 (ko) * | 2008-02-29 | 2010-09-08 | 고려대학교 산학협력단 | 제8 혈액응고 인자와 폰 빌리 블란트 인자 변이체의 재조합발현 벡터 시스템 |
| WO2010075303A1 (en) * | 2008-12-23 | 2010-07-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Splicing factors with a puf protein rna-binding domain and a splicing effector domain and uses of same |
| US8147820B2 (en) | 2009-09-14 | 2012-04-03 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Attenuated vaccine against fish pathogen Francisella sp |
| RU2579977C2 (ru) | 2009-11-13 | 2016-04-10 | Грифольс Терапьютикс Инк. | СОДЕРЖАЩИЕ ФАКТОР ФОН ВИЛЛЕБРАНДА (vWF) ПРЕПАРАТЫ И СПОСОБЫ, НАБОРЫ И ПРИМЕНЕНИЯ, СВЯЗАННЫЕ С НИМИ |
| US20120225028A1 (en) * | 2011-03-02 | 2012-09-06 | Moshe Cohen | Compositions and methods for mobilization of stem cells |
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| EP2912186A4 (en) | 2016-06-08 |
| US10294291B2 (en) | 2019-05-21 |
| KR20150069017A (ko) | 2015-06-22 |
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| JP2018161152A (ja) | 2018-10-18 |
| WO2014066663A1 (en) | 2014-05-01 |
| US9982034B2 (en) | 2018-05-29 |
| US20240270822A1 (en) | 2024-08-15 |
| PL2912186T3 (pl) | 2021-06-14 |
| ES2854754T3 (es) | 2021-09-22 |
| DK2912186T3 (da) | 2021-02-22 |
| US20150344541A1 (en) | 2015-12-03 |
| JP6975105B2 (ja) | 2021-12-01 |
| IL238417B (en) | 2019-07-31 |
| EP3859004A1 (en) | 2021-08-04 |
| BR112015009229A2 (pt) | 2017-11-14 |
| CA2888982A1 (en) | 2014-05-01 |
| EP2912186A1 (en) | 2015-09-02 |
| US20180009874A1 (en) | 2018-01-11 |
| JP2016501515A (ja) | 2016-01-21 |
| ZA201502945B (en) | 2016-11-30 |
| US20190270791A1 (en) | 2019-09-05 |
| IL238417A0 (en) | 2015-06-30 |
| BR112015009229B1 (pt) | 2021-07-20 |
| HK1211986A1 (en) | 2016-06-03 |
| EP2912186B1 (en) | 2021-01-06 |
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