CA2885334C - Antimicrobial articles produced by additive manufacturing - Google Patents

Antimicrobial articles produced by additive manufacturing Download PDF

Info

Publication number
CA2885334C
CA2885334C CA2885334A CA2885334A CA2885334C CA 2885334 C CA2885334 C CA 2885334C CA 2885334 A CA2885334 A CA 2885334A CA 2885334 A CA2885334 A CA 2885334A CA 2885334 C CA2885334 C CA 2885334C
Authority
CA
Canada
Prior art keywords
antibiotic
amino
acid
article
methanesulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2885334A
Other languages
English (en)
French (fr)
Other versions
CA2885334A1 (en
Inventor
Martin Petrak
Luke M. B. Rodgers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ORTHOPAEDIC INNOVATION CENTRE Inc
Original Assignee
ORTHOPAEDIC INNOVATION CENTRE Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50730434&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2885334(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ORTHOPAEDIC INNOVATION CENTRE Inc filed Critical ORTHOPAEDIC INNOVATION CENTRE Inc
Publication of CA2885334A1 publication Critical patent/CA2885334A1/en
Application granted granted Critical
Publication of CA2885334C publication Critical patent/CA2885334C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/37512—Pacemakers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/022—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the choice of material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0205—Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/04—General characteristics of the apparatus implanted
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Mechanical Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Dentistry (AREA)
  • Prostheses (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
CA2885334A 2012-11-14 2013-11-14 Antimicrobial articles produced by additive manufacturing Expired - Fee Related CA2885334C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261726433P 2012-11-14 2012-11-14
US61/726,433 2012-11-14
US201361895130P 2013-10-24 2013-10-24
US61/895,130 2013-10-24
PCT/CA2013/050871 WO2014075185A1 (en) 2012-11-14 2013-11-14 Antimicrobial articles produced by additive manufacturing

Publications (2)

Publication Number Publication Date
CA2885334A1 CA2885334A1 (en) 2014-05-22
CA2885334C true CA2885334C (en) 2016-03-08

Family

ID=50730434

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2885334A Expired - Fee Related CA2885334C (en) 2012-11-14 2013-11-14 Antimicrobial articles produced by additive manufacturing

Country Status (12)

Country Link
US (2) US10905740B2 (enExample)
EP (1) EP2919823B1 (enExample)
JP (1) JP2015536726A (enExample)
KR (1) KR20150090110A (enExample)
CN (2) CN109453433A (enExample)
AU (1) AU2013344733B2 (enExample)
BR (1) BR112015010877A2 (enExample)
CA (1) CA2885334C (enExample)
IL (1) IL238848B (enExample)
IN (1) IN2015DN04046A (enExample)
MX (1) MX2015006002A (enExample)
WO (1) WO2014075185A1 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8933145B2 (en) 2009-02-20 2015-01-13 The General Hospital Corporation High temperature melting
IN2015DN04046A (enExample) 2012-11-14 2015-10-02 Orthopaedic Innovation Ct Inc
TWI522430B (zh) * 2014-02-20 2016-02-21 研能科技股份有限公司 立體成型組合物
US10406263B2 (en) 2014-03-25 2019-09-10 Orthopaedic Innovation Centre Inc. Antimicrobial articles produced by additive manufacturing
WO2015179325A1 (en) * 2014-05-18 2015-11-26 Lacerda Carlos M Antibacterial composition, antibacterial cases and accessories for handheld electronics, and method of making antibacterial cases for handheld electronics
WO2016022661A1 (en) * 2014-08-05 2016-02-11 University Of Washington Three-dimensional printed mechanoresponsive materials and related methods
US10441689B2 (en) 2014-08-10 2019-10-15 Louisiana Tech Research Corporation Methods and devices for three-dimensional printing or additive manufacturing of bioactive medical devices
KR101701498B1 (ko) * 2014-09-05 2017-02-03 (주)비앤케이 항균성을 가지는 3d 프린터용 필라멘트 제조 방법 및 이에 의해 제조된 항균성을 가지는 3d 프린터용 필라멘트
US11771655B2 (en) 2014-09-08 2023-10-03 University Of Central Lancashire Solid dosage form production
CN104260359B (zh) * 2014-09-16 2016-09-07 苏州佳世达光电有限公司 3d打印机及其光源选取方法
JP6537250B2 (ja) * 2014-11-13 2019-07-03 ユニチカ株式会社 ポリ乳酸系モノフィラメント
US9757573B2 (en) * 2014-12-02 2017-09-12 Heraeus Deutschland GmbH & Co. KG Implantable medical device housing having integrated features
CH710441A2 (de) 2014-12-02 2016-06-15 Rowak Ag Pulverförmige Zusammensetzungen aus thermoplastischen Kunststoffen und Verwendung der Zusammensetzungen.
JP6770774B2 (ja) * 2014-12-09 2020-10-21 ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー 骨再生のための３次元足場
WO2016132289A1 (en) * 2015-02-16 2016-08-25 Tecres S.P.A. Material for the molding of devices to be implanted into the human body or of articular spacers
US12291823B2 (en) * 2015-04-15 2025-05-06 Robert A. Flitsch Methods, materials and apparatus for mobile additive manufacturing of advanced structures and roadways
US20180168811A1 (en) * 2015-06-15 2018-06-21 Rowan University Novel biodegradable and non-biodegradable 3d printed implants as a drug delivery system
EP3325530A1 (en) * 2015-07-17 2018-05-30 Lubrizol Advanced Materials, Inc. Thermoplastic polyurethane compositions for solid freeform fabrication
KR20180029246A (ko) * 2015-07-17 2018-03-20 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 고체 임의 형상 제작을 위한 열가소성 폴리우레탄 조성물
GB201516943D0 (en) 2015-09-24 2015-11-11 Victrex Mfg Ltd Polymeric materials
US12350403B2 (en) * 2015-11-12 2025-07-08 The General Hospital Corporation Methods of making therapeutic polymeric material
KR20180095853A (ko) 2015-12-16 2018-08-28 너바시브 인코퍼레이티드 다공성 척추 융합 임플란트
CN105457103B (zh) * 2015-12-31 2019-04-02 复旦大学附属华山医院 一种3d打印周围神经导管及其制备方法
GB201601865D0 (en) * 2016-02-02 2016-03-16 Ucl Business Plc Oral dosage products and processes
US12115289B2 (en) 2016-02-05 2024-10-15 The General Hospital Corporation Drug eluting polymer composed of biodegradable polymers applied to surface of medical device
CA3018012A1 (en) * 2016-03-18 2017-09-21 Grunenthal Gmbh Combination of drugs having different potency
US9863065B2 (en) 2016-04-13 2018-01-09 Xerox Corporation Polymer coated sulfonated polyester—silver nanoparticle composite filaments and methods of making the same
US9908977B2 (en) 2016-04-13 2018-03-06 Xerox Corporation Styrenic-based polymer coated silver nanoparticle-sulfonated polyester composite powders and methods of making the same
US9877485B2 (en) 2016-04-13 2018-01-30 Xerox Corporation Silver polyester-sulfonated nanoparticle composite filaments and methods of making the same
US9909013B2 (en) 2016-04-13 2018-03-06 Xerox Corporation Silver nanoparticle-sulfonated polyester composite powders and methods of making the same
ES2857858T3 (es) * 2016-04-28 2021-09-29 Straumann Holding Ag Sistema y procedimiento de fabricación de un dispositivo dental
DE102016110500B4 (de) * 2016-06-07 2019-03-14 Karl Leibinger Medizintechnik Gmbh & Co. Kg Implantatherstellverfahren mittels additivem selektivem Lasersintern und Implantat
US10405540B2 (en) 2016-07-06 2019-09-10 Xerox Corporation Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same
US10113059B2 (en) 2016-07-06 2018-10-30 Xerox Corporation Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same
RU2753283C2 (ru) 2016-09-08 2021-08-12 Карл Лайбингер Медицинтехник Гмбх Унд Ко. Кг Способ изготовления имплантата с использованием композиционного порошка, содержащего карбонат кальция с микроструктурированными частицами
US11471566B2 (en) * 2016-09-08 2022-10-18 Karl Leibinger Medizintechnik Gmbh & Co. Kg Implant comprising a calcium salt-containing composite powder having microstructured particles
US9875958B1 (en) * 2016-11-09 2018-01-23 International Business Machines Corporation Trace/via hybrid structure and method of manufacture
EP3320898A1 (en) * 2016-11-11 2018-05-16 ratiopharm GmbH Dosage form comprising a carrier structure and method for manufacturing the dosage form
CN106727692A (zh) * 2016-11-24 2017-05-31 浙江三禾纳米科技有限公司 一种皮肤抗菌喷剂及其制备方法
US10786605B2 (en) * 2016-12-18 2020-09-29 Cardiac Pacemakers, Inc. Infection fighting drug eluting lead boot
US11229605B2 (en) 2017-02-15 2022-01-25 Hewlett-Packard Development Company, L.P. Printed support structure
CN110730800B (zh) 2017-05-26 2022-08-19 无限材料解决方案有限公司 水性聚合物组合物
RU2020107391A (ru) 2017-07-25 2021-08-25 Пк Мед Сас Способ получения композиции для доставки лекарственного средства
CN111630144B (zh) 2018-02-22 2021-12-31 宝洁公司 用于制备单位剂量制品的方法
US11453197B2 (en) * 2018-07-03 2022-09-27 Hamilton Sundstrand Corporation Antimicrobial surfaces for flow path components
WO2020181205A1 (en) 2019-03-07 2020-09-10 Board Of Regents Of The University Of Nebraska Antimicrobial scaffolds
CN110180033A (zh) * 2019-05-16 2019-08-30 深圳市第二人民医院 载甲基莲心碱的三维多孔支架及其制备方法
RU196412U1 (ru) * 2019-10-02 2020-02-28 Владимир Юрьевич Гречухин Устройство синхронизации работы деструктора и насоса для подачи охлаждающей жидкости
US20230058297A1 (en) * 2020-02-05 2023-02-23 3D Implants, Incubatee, Foundation For Innovation & Research At Sastra Technology Business Incubator Fabrication of 3d-printed fracture-specific orthopaedic cast
MX2022010903A (es) 2020-03-04 2022-11-30 Ascend Performance Mat Operations Llc Composiciones, fibras y productos de polímero antivirales/antimicrobianos.
US12371581B2 (en) 2020-03-25 2025-07-29 Infinite Material Solutions, Llc High performance water soluble polymer compositions
CN111995847A (zh) * 2020-07-31 2020-11-27 陕西科技大学 一种可抗菌的3d打印线材的制备方法
CN112334539A (zh) * 2020-08-13 2021-02-05 香港理工大学 三维打印抗菌产品
CN112743835B (zh) * 2020-12-25 2022-07-01 聊城市东昌府区妇幼保健院 一种医用护具及其制造方法
US11970600B2 (en) 2021-03-31 2024-04-30 The General Hospital Corporation Di-cumyl peroxide crosslinking of UHMWPE
DE102021214529A1 (de) 2021-12-16 2023-06-22 Volkswagen Aktiengesellschaft Filament-Element für additive Fertigungsverfahren, Extrudiervorrichtung zur Herstellung eines Filament-Elements, Produktionsvorrichtung zur additiven Herstellung von 3D-Bauteilen

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642003A (en) 1969-08-26 1972-02-15 Sutures Inc Sutures having long-lasting germicidal properties
US3862304A (en) 1971-06-03 1975-01-21 Sutures Inc Sutures having long-lasting germicidal properties
JP3119509B2 (ja) * 1991-09-20 2000-12-25 ユニチカ株式会社 水中資材用繊維
US5217493A (en) 1992-03-11 1993-06-08 Board Of Regents, The University Of Texas System Antibacterial coated medical implants
US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US5490962A (en) 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
US5626611A (en) * 1994-02-10 1997-05-06 United States Surgical Corporation Composite bioabsorbable materials and surgical articles made therefrom
DE19527630A1 (de) 1995-07-28 1997-01-30 Hoechst Ag Polyhydroxyalkylamidobetaine
US6341952B2 (en) * 1997-03-20 2002-01-29 Therics, Inc. Fabrication of tissue products with additives by casting or molding using a mold formed by solid free-form methods
US20050023710A1 (en) * 1998-07-10 2005-02-03 Dmitri Brodkin Solid free-form fabrication methods for the production of dental restorations
CA2345982A1 (en) * 1998-10-12 2000-04-20 Jill K. Sherwood Composites for tissue regeneration and methods of manufacture thereof
CN1378445B (zh) * 1999-08-06 2013-02-06 得克萨斯系统大学评议会 药物释放生物可降解纤维植入物
AU2002305201A1 (en) * 2001-04-19 2002-11-05 Case Western Reserve University Fabrication of a polymeric prosthetic implant
WO2003034314A1 (en) 2001-10-15 2003-04-24 The Regents Of The University Of Michigan Solid freeform fabrication of structurally engineered multifunctional devices
US7509240B2 (en) * 2001-10-15 2009-03-24 The Regents Of The University Of Michigan Solid freeform fabrication of structurally engineered multifunctional devices
EP1608292A4 (en) 2003-03-13 2007-10-31 Univ Rice William M INJECTABLE AND PRE-PRODUCED COMPOSITE MATERIAL AS A BONE REPLACEMENT AND METHOD FOR PRODUCING SUCH A BONE REPLACEMENT MATERIAL
ATE447981T1 (de) 2003-07-17 2009-11-15 Bioretec Oy Synthetische, bioabsorbierbare polymer- materialien und implantate
AU2004291022C1 (en) * 2003-11-21 2009-11-12 Osteopore International Pte Ltd Bioabsorbable plug implants and method for bone tissue regeneration
US7357810B2 (en) * 2003-12-18 2008-04-15 Ethicon, Inc. High strength suture with absorbable core and suture anchor combination
EP1729783B2 (en) * 2004-03-24 2023-01-18 Polynovo Biomaterials Pty Limited Biodegradable polyurethane and polyurethane ureas
CN105233349B (zh) * 2005-07-15 2019-06-18 胶束技术股份有限公司 包含受控形态的药物粉末的聚合物涂层
AU2006308534B2 (en) * 2005-11-01 2013-02-07 Warsaw Orthopedic, Inc. Bone matrix compositions and methods
FR2898039B1 (fr) 2006-03-03 2008-06-27 Ceravic Sas Soc Par Actions Si Implant provisoire comprenant deux actifs.
US8178012B1 (en) * 2006-04-06 2012-05-15 Ivoclar Vivadent Ag Shaded zirconium oxide articles and methods
DE102006017595A1 (de) * 2006-04-13 2007-10-18 Friedrich-Baur Gmbh Verfahren zum Herstellen eines biokompatiblen Gerüstes, insbesondere zur Herstellung eines Implantates
US8974814B2 (en) * 2007-11-12 2015-03-10 California Institute Of Technology Layered drug delivery polymer monofilament fibers
JP2011530387A (ja) * 2008-08-14 2011-12-22 アーケマ・インコーポレイテッド 骨置換用のカスタマイズされたインプラント
AU2010272167B2 (en) * 2009-07-14 2016-11-17 Polypid Ltd. Sustained-release drug carrier composition
IL203403A (en) * 2010-01-19 2016-08-31 Cupron Inc Biofilm resistant materials
KR101879438B1 (ko) * 2010-08-20 2018-08-17 케이스 웨스턴 리저브 유니버시티 이식물의 ｃＤＬＰ 첨삭 가공
US8920697B2 (en) 2010-09-17 2014-12-30 Stratasys, Inc. Method for building three-dimensional objects in extrusion-based additive manufacturing systems using core-shell consumable filaments
WO2012052020A1 (en) 2010-10-19 2012-04-26 Aarhus Universitet Tissue scaffold with controlled drug release
CN102302386B (zh) 2011-06-24 2013-10-16 上海大学 药物缓释型仿生骨支架的制备方法
IN2015DN04046A (enExample) 2012-11-14 2015-10-02 Orthopaedic Innovation Ct Inc

Also Published As

Publication number Publication date
WO2014075185A1 (en) 2014-05-22
CN105050632A (zh) 2015-11-11
BR112015010877A2 (pt) 2017-07-11
AU2013344733A1 (en) 2015-05-28
EP2919823A4 (en) 2016-07-13
IN2015DN04046A (enExample) 2015-10-02
US20150290280A1 (en) 2015-10-15
AU2013344733B2 (en) 2017-02-23
MX2015006002A (es) 2016-02-05
IL238848B (en) 2019-10-31
KR20150090110A (ko) 2015-08-05
JP2015536726A (ja) 2015-12-24
EP2919823B1 (en) 2019-07-03
CA2885334A1 (en) 2014-05-22
CN109453433A (zh) 2019-03-12
US11666626B2 (en) 2023-06-06
EP2919823A1 (en) 2015-09-23
IL238848A0 (en) 2015-06-30
US10905740B2 (en) 2021-02-02
US20210113651A1 (en) 2021-04-22

Similar Documents

Publication Publication Date Title
US11666626B2 (en) Antimicrobial articles produced by additive manufacturing
CA2943416C (en) Antimicrobial articles produced by additive manufacturing
US10441689B2 (en) Methods and devices for three-dimensional printing or additive manufacturing of bioactive medical devices
JP2015536726A5 (enExample)
EP2114298B1 (en) Temporarily stiffened mesh prostheses
US20200030491A1 (en) Methods and Devices For Three-Dimensional Printing Or Additive Manufacturing Of Bioactive Medical Devices
AU2015247588B2 (en) Methods for coating implant surfaces to treat surgical infections
JP6456935B2 (ja) フィルム及び製造方法
EP3258976B1 (en) Material for the molding of devices to be implanted into the human body or of articular spacers
US20210301135A1 (en) Nitric oxide-releasing 3d-printing compositions and uses thereof
US20200061239A1 (en) Antimicrobial articles produced by additive manufacturing
US20240183081A1 (en) Method for obtaining a thread in order to produce devices to be implanted into the human body
US20230414836A1 (en) Devices to be implanted into the human body
CA2637578C (en) Temporarily stiffened mesh prostheses
WO2012009665A1 (en) Temporary bone filler

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150318

MKLA Lapsed

Effective date: 20191114