IN2015DN04046A - - Google Patents

Info

Publication number
IN2015DN04046A
IN2015DN04046A IN4046DEN2015A IN2015DN04046A IN 2015DN04046 A IN2015DN04046 A IN 2015DN04046A IN 4046DEN2015 A IN4046DEN2015 A IN 4046DEN2015A IN 2015DN04046 A IN2015DN04046 A IN 2015DN04046A
Authority
IN
India
Prior art keywords
pump
antibiotic
delivery
polymeric material
additive manufacturing
Prior art date
Application number
Inventor
Martin Petrak
Luke Rodgers
Original Assignee
Orthopaedic Innovation Ct Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50730434&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2015DN04046(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orthopaedic Innovation Ct Inc filed Critical Orthopaedic Innovation Ct Inc
Publication of IN2015DN04046A publication Critical patent/IN2015DN04046A/en

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Classifications

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    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing

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Abstract

An antibiotic eluting article for implantation into a mammalian subject produced by an additive manufacturing process wherein a polymeric material is concurrently deposited with a selected antibiotic. The additive manufacturing process may be a fused deposition modeling process a selective laser sintering process a selective heat sintering process a digital light processing process or a stereolithography process. The antibiotic eluting article may be temporary or permanent orthopaedic skeletal component an orthopaedic articulating joint replacement component and/or an external hard shell casing for an implantable device. One or more bone growth promoting compositions may be concurrently deposited with the polymeric material. The implantable device may be a cardiac pacemaker a spinal cord stimulator a neurostimulation system an intrathecal drug pump for delivery of medicants into the spinal fluid and infusion pump for delivery of chemotherapeutics and/or anti spasmodics an insulin pump an osmotic pump and a heparin pump.
IN4046DEN2015 2012-11-14 2013-11-14 IN2015DN04046A (en)

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PCT/CA2013/050871 WO2014075185A1 (en) 2012-11-14 2013-11-14 Antimicrobial articles produced by additive manufacturing

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Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010096771A2 (en) 2009-02-20 2010-08-26 The General Hospital Corporation Dba High temperature melting
CA2885334C (en) 2012-11-14 2016-03-08 Orthopaedic Innovation Centre Inc. Antimicrobial articles produced by additive manufacturing
TWI522430B (en) * 2014-02-20 2016-02-21 研能科技股份有限公司 Three dimensional prototyping composition
AU2015234581B2 (en) * 2014-03-25 2018-06-21 Orthopaedic Innovation Centre Inc. Antimicrobial articles produced by additive manufacturing
MX2016015171A (en) * 2014-05-18 2017-07-14 M Lacerda Carlos Antibacterial composition, antibacterial cases and accessories for handheld electronics, and method of making antibacterial cases for handheld electronics.
WO2016022661A1 (en) * 2014-08-05 2016-02-11 University Of Washington Three-dimensional printed mechanoresponsive materials and related methods
WO2016025388A1 (en) * 2014-08-10 2016-02-18 Louisiana Tech University Foundation; A Division Of Louisiana Tech University Foundation , Inc. Methods and devices for three-dimensional printing or additive manufacturing of bioactive medical devices
KR101701498B1 (en) * 2014-09-05 2017-02-03 (주)비앤케이 manufacturing method of 3D printer filament having antibacterial effects and 3D printer filament with antibacterial effects.
CN107107463B (en) * 2014-09-08 2019-10-25 中央兰开夏大学 Solid dosage forms production
CN104260359B (en) * 2014-09-16 2016-09-07 苏州佳世达光电有限公司 3D printer and light source choosing method thereof
JP6537250B2 (en) * 2014-11-13 2019-07-03 ユニチカ株式会社 Polylactic acid monofilament
US9757573B2 (en) * 2014-12-02 2017-09-12 Heraeus Deutschland GmbH & Co. KG Implantable medical device housing having integrated features
CH710441A2 (en) 2014-12-02 2016-06-15 Rowak Ag Powdered compositions of thermoplastics and use of the compositions.
JP6770774B2 (en) * 2014-12-09 2020-10-21 ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー 3D scaffolding for bone regeneration
US20180168811A1 (en) * 2015-06-15 2018-06-21 Rowan University Novel biodegradable and non-biodegradable 3d printed implants as a drug delivery system
WO2017015073A1 (en) * 2015-07-17 2017-01-26 Lubrizol Advanced Materials, Inc. Thermoplastic polyurethane compositions for solid freeform fabrication
CR20180018A (en) * 2015-07-17 2018-03-08 Lubrizol Advanced Mat Inc COMPOSITIONS OF THERMOPLASTIC POLYURETHANE FOR MANUFACTURING IN SOLID FORM
GB201516943D0 (en) * 2015-09-24 2015-11-11 Victrex Mfg Ltd Polymeric materials
US20180318468A1 (en) * 2015-11-12 2018-11-08 The Gereral Hospital Corporation Methods of making therapeutic polymeric material
CN112842636A (en) 2015-12-16 2021-05-28 纽文思公司 Porous spinal fusion implant
CN105457103B (en) * 2015-12-31 2019-04-02 复旦大学附属华山医院 A kind of 3D printing peripheral nerve conduit and preparation method thereof
GB201601865D0 (en) * 2016-02-02 2016-03-16 Ucl Business Plc Oral dosage products and processes
WO2017158172A1 (en) * 2016-03-18 2017-09-21 Grünenthal GmbH Combination of drugs having different potency
US9863065B2 (en) 2016-04-13 2018-01-09 Xerox Corporation Polymer coated sulfonated polyester—silver nanoparticle composite filaments and methods of making the same
US9908977B2 (en) 2016-04-13 2018-03-06 Xerox Corporation Styrenic-based polymer coated silver nanoparticle-sulfonated polyester composite powders and methods of making the same
US9909013B2 (en) 2016-04-13 2018-03-06 Xerox Corporation Silver nanoparticle-sulfonated polyester composite powders and methods of making the same
US9877485B2 (en) 2016-04-13 2018-01-30 Xerox Corporation Silver polyester-sulfonated nanoparticle composite filaments and methods of making the same
BR112018072119A2 (en) * 2016-04-28 2019-02-12 Straumann Holding Ag system and method for dental device manufacturing
DE102016110500B4 (en) * 2016-06-07 2019-03-14 Karl Leibinger Medizintechnik Gmbh & Co. Kg Implant fabrication by additive selective laser sintering and implant
US10113059B2 (en) 2016-07-06 2018-10-30 Xerox Corporation Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same
US10405540B2 (en) * 2016-07-06 2019-09-10 Xerox Corporation Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same
WO2018046238A1 (en) * 2016-09-08 2018-03-15 Karl Leibinger Medizintechnik Gmbh & Co. Kg Implant comprising a calcium salt-containing composite powder having microstructred particles
US11318229B2 (en) 2016-09-08 2022-05-03 Karl Leibinger Medizintechnik Gmbh & Co. Kg Method for producing an implant using a calcium carbonate-containing composite powder comprising microstructured particles
US9875958B1 (en) * 2016-11-09 2018-01-23 International Business Machines Corporation Trace/via hybrid structure and method of manufacture
EP3320898A1 (en) * 2016-11-11 2018-05-16 ratiopharm GmbH Dosage form comprising a carrier structure and method for manufacturing the dosage form
CN106727692A (en) * 2016-11-24 2017-05-31 浙江三禾纳米科技有限公司 A kind of antibacterial skin spray and preparation method thereof
CN110087726A (en) * 2016-12-18 2019-08-02 心脏起搏器股份公司 Anti-infectives elute lead casing
WO2018151725A1 (en) * 2017-02-15 2018-08-23 Hewlett-Packard Development Company, L.P. Printed support structure
CN110730800B (en) 2017-05-26 2022-08-19 无限材料解决方案有限公司 Aqueous polymer composition
SG11202000497VA (en) 2017-07-25 2020-02-27 PK Med SAS Process for preparing a drug delivery composition
US11453197B2 (en) * 2018-07-03 2022-09-27 Hamilton Sundstrand Corporation Antimicrobial surfaces for flow path components
WO2020181205A1 (en) * 2019-03-07 2020-09-10 Board Of Regents Of The University Of Nebraska Antimicrobial scaffolds
CN110180033A (en) * 2019-05-16 2019-08-30 深圳市第二人民医院 Carry the three-dimensional porous rack and preparation method thereof of neferine
RU196412U1 (en) * 2019-10-02 2020-02-28 Владимир Юрьевич Гречухин Device for synchronizing the operation of the destructor and the pump for supplying coolant
WO2021156894A1 (en) * 2020-02-05 2021-08-12 3D Implants Fabrication of 3d-printed fracture-specific orthopaedic cast
EP4114186A1 (en) 2020-03-04 2023-01-11 Ascend Performance Materials Operations LLC Antiviral/antimicrobial polymer compositions, fibers, and products
CN111995847A (en) * 2020-07-31 2020-11-27 陕西科技大学 Preparation method of antibacterial 3D printing wire
CN112743835B (en) * 2020-12-25 2022-07-01 聊城市东昌府区妇幼保健院 Medical protective clothing and manufacturing method thereof
US11970600B2 (en) 2021-03-31 2024-04-30 The General Hospital Corporation Di-cumyl peroxide crosslinking of UHMWPE
DE102021214529A1 (en) 2021-12-16 2023-06-22 Volkswagen Aktiengesellschaft Filament element for additive manufacturing processes, extrusion device for manufacturing a filament element, production device for additive manufacturing of 3D components

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642003A (en) 1969-08-26 1972-02-15 Sutures Inc Sutures having long-lasting germicidal properties
US3862304A (en) 1971-06-03 1975-01-21 Sutures Inc Sutures having long-lasting germicidal properties
JP3119509B2 (en) * 1991-09-20 2000-12-25 ユニチカ株式会社 Fiber for underwater materials
US5217493A (en) 1992-03-11 1993-06-08 Board Of Regents, The University Of Texas System Antibacterial coated medical implants
US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US5490962A (en) 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
US5626611A (en) * 1994-02-10 1997-05-06 United States Surgical Corporation Composite bioabsorbable materials and surgical articles made therefrom
DE19527630A1 (en) 1995-07-28 1997-01-30 Hoechst Ag Polyhydroxyalkyl amido betaines
US6341952B2 (en) * 1997-03-20 2002-01-29 Therics, Inc. Fabrication of tissue products with additives by casting or molding using a mold formed by solid free-form methods
US20050023710A1 (en) * 1998-07-10 2005-02-03 Dmitri Brodkin Solid free-form fabrication methods for the production of dental restorations
JP2002527144A (en) * 1998-10-12 2002-08-27 セリックス， インコーポレイテッド Composite for tissue regeneration and method for producing the same
US6596296B1 (en) * 1999-08-06 2003-07-22 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
AU2002305201A1 (en) * 2001-04-19 2002-11-05 Case Western Reserve University Fabrication of a polymeric prosthetic implant
WO2003034314A1 (en) 2001-10-15 2003-04-24 The Regents Of The University Of Michigan Solid freeform fabrication of structurally engineered multifunctional devices
US7509240B2 (en) 2001-10-15 2009-03-24 The Regents Of The University Of Michigan Solid freeform fabrication of structurally engineered multifunctional devices
US20070065652A1 (en) 2003-03-13 2007-03-22 Willaim Marsh Rice University Composite injectable and pre-fabricated bone replacement material and method for the production of such bone replacement material
DE602004024069D1 (en) * 2003-07-17 2009-12-24 Bioretec Oy SYNTHETIC, BIOABSORBABLE POLYMER MATERIALS AND IMPLANTS
US20070083268A1 (en) * 2003-11-21 2007-04-12 Osteopore International Pte Ltd Bioabsorbable plug implants and method for bone tissue regeneration
US7357810B2 (en) * 2003-12-18 2008-04-15 Ethicon, Inc. High strength suture with absorbable core and suture anchor combination
US9034378B2 (en) * 2004-03-24 2015-05-19 Polynovo Biomaterials Pty Ltd Biodegradable polyurethane and polyurethane ureas
US8298565B2 (en) * 2005-07-15 2012-10-30 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
WO2007053850A2 (en) * 2005-11-01 2007-05-10 Osteotech, Inc. Bone matrix compositions and methods
FR2898039B1 (en) 2006-03-03 2008-06-27 Ceravic Sas Soc Par Actions Si PROVISIONAL IMPLANT COMPRISING TWO ASSETS.
US8178012B1 (en) * 2006-04-06 2012-05-15 Ivoclar Vivadent Ag Shaded zirconium oxide articles and methods
DE102006017595A1 (en) * 2006-04-13 2007-10-18 Friedrich-Baur Gmbh Method for producing a biocompatible scaffold, in particular for producing an implant
US8974814B2 (en) 2007-11-12 2015-03-10 California Institute Of Technology Layered drug delivery polymer monofilament fibers
JP2011530387A (en) * 2008-08-14 2011-12-22 アーケマ・インコーポレイテッド Customized implants for bone replacement
AU2010272167B2 (en) * 2009-07-14 2016-11-17 Polypid Ltd. Sustained-release drug carrier composition
IL203403A (en) * 2010-01-19 2016-08-31 Cupron Inc Biofilm resistant materials
MX366709B (en) * 2010-08-20 2019-07-22 Rice Univ Star Continuous digital light processing additive manufacturing of implants.
US8920697B2 (en) 2010-09-17 2014-12-30 Stratasys, Inc. Method for building three-dimensional objects in extrusion-based additive manufacturing systems using core-shell consumable filaments
WO2012052020A1 (en) 2010-10-19 2012-04-26 Aarhus Universitet Tissue scaffold with controlled drug release
CN102302386B (en) 2011-06-24 2013-10-16 上海大学 Preparation method of slow-releasing drug type bionic bone scaffold
CA2885334C (en) 2012-11-14 2016-03-08 Orthopaedic Innovation Centre Inc. Antimicrobial articles produced by additive manufacturing

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